Abstract
Estrogen receptor (ESR) and Follicular-stimulating hormone beta subunit (FSHβ) genes were chosen as candidates to determine whether they control litter size and some other reproductive traits in swine. 269 sows from five different pig breeds were genotyped by an established PCR-RFLPs protocol at both ESR and FSHβ loci. The effects of both ESR and FSHβ on pig reproductive traits, including total number born (TNB) and number born alive (NBA), are analyzed by SAS software (version 6.12). These computation results demonstrated that both ESR locus and FSHβ locus are the major genes influencing litter size in pigs. The sows of BBBB combined genotype of ESR and FSHβ loci generally produce 1.85–3.01 TNB and 2.0–3.0 NBA more than those of ABAA combined genotype. The notable effect of ESR locus and FSHβ locus on litter size of pigs have made it possible to inprove the pig reproduction by Marker-assisted selection (MAS). Moreover, introgression of the beneficial alleles into commercial pig breeding lines, in which the alleles were not present, will improve greatly the economically important reproductive traits and efficiency of pig production.
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Chen, K., Li, N., Huang, L. et al. The combined genotypes effect of ESR and FSHβ genes on litter size traits in five different pig breeds. Chin.Sci.Bull. 46, 140–143 (2001). https://doi.org/10.1007/BF03187010
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DOI: https://doi.org/10.1007/BF03187010