Skip to main content
Log in

Selective testosterone secreting adrenocortical carcinoma in an infant

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Adrenocortical carcinoma in children is a rare tumor of adrenal gland. An infant presented with signs of virilization due to selective testosterone hypersecretion. Diagnosis was established with the help of the computerized tomographic scan and histopathological examination. Following adrenalectomy patient made uneventful recovery and six months later does not have any clinical or laboratory evidence of recurrence or metastasis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. John L, Young PH Jr, Miller RW. Incidence of malignant tumors in US children.J Paediatr 1975; 86: 254–258.

    Article  Google Scholar 

  2. Vasiloff J, Chideckel EW, Baid CB, Foshag LJ. Testosterone secreting adrenal adenoma containing crystalloid characteristic of leydig cells.Am J Med 1985; 79: 772–776.

    Article  PubMed  CAS  Google Scholar 

  3. Kamilaris TC, Debold CR, Manolas KJ, Hoursanidis A, Panageas S, Yiamnatos J. Testosterone secreting adrenal adenoma in a peripubertal girl.JAMA 1987; 258: 2558–2561.

    Article  PubMed  CAS  Google Scholar 

  4. Sorg OW, Meyer D, Rodenset al. Testosterone secreting adrenocortical tumor in a pubertal girl. Case report and review of literature.Hormone Research 1988; 30: 217–223.

    Article  Google Scholar 

  5. Ribeiro RC, Neto RS, Schell MJ, Lacerda L, Sambaio GA, Cat I. Adrenocortical carcinoma in children: A study of 40 cases.J Clin Oncol 1990; 8: 67–74.

    PubMed  CAS  Google Scholar 

  6. Shenoy PD, Patil UD, Ghosh MK, Lakhar BN, Pai KD. Adrenocortical carcinoma in children — A case report of 3 cases.Indian J Cancer 1991; 28: 114–117.

    PubMed  CAS  Google Scholar 

  7. Lee PKD, Winter RJ, Green OC. Virilizing Adrenocortical Tumors in childhood: Eight cases and a review of the literature.Pediatrics 1985; 76: 437–444.

    PubMed  CAS  Google Scholar 

  8. Jones GS, Shah KJ, Mann JR. Adrenocortical carcinoma in infancy and childhood: A radiological report of ten cases.Clin Radiol 1985; 36 : 257–262.

    Article  PubMed  CAS  Google Scholar 

  9. Kay R. Schumacher OP. Tank ES. Adrenocortical tumor in children.J Urol 1983; 130: 1130–1132.

    PubMed  CAS  Google Scholar 

  10. Fraumeni JF Jr, Miller RW. Adrenocortical neoplasms with hemihypertrophy, brain tumor and other disorders.J Pediatr 1967; 70: 129–138.

    Article  PubMed  Google Scholar 

  11. Petrus LV, Hall TR, Boechat MI,et al. The pediatric patient with suspected adrenal neoplasm: which radiological test to use?Med Pediatric Oncol 1992; 20: 53–57.

    Article  CAS  Google Scholar 

  12. Burr LM. Sullivan J, Graham T, Hartman WI, O’Neill J. Testosterone-secreting tumor of the adrenal producing virilization in a female infant.Lancet 1973 : 643–644.

  13. Kamilaris TC, DeBold R, Manolas KJ, Hoursanidis A, Panagea SS, Yiannatos J. Testosterone-secreting Adrenal Adenoma in a peripubertal girl.JAMA 1987; 258: 2558–2561.

    Article  PubMed  CAS  Google Scholar 

  14. Kelly TR, Mayors DJ, Boutsicaris PS. Adrenal adenoma: isolated testosterone secretion.Am Surg 1982; 48: 604–606.

    PubMed  CAS  Google Scholar 

  15. Dollnar R, Burch WM. Testosterone — producing adrenal adenoma in a woman with normal urinary 17 — ketosteroid levels.JAMA 1983; 250: 2504–2505.

    Article  Google Scholar 

  16. Crucitti F, Bellantone R, Ferrante A, Boscherini M, Crucitti P. The ACC Italian Registry Study Group. The Italian Registry for adrenal cortical carcinoma: Analysis of a multi-institutional series of patients.Surgery 1996; 119: 161–170.

    Article  PubMed  CAS  Google Scholar 

  17. Arico M, Bossi G, Livieri C, Raiteri E, Severi P. Partial response after intensive chemotherapy for adrenal cortical carcinoma in a child.Med Pediatric Oncol 1992; 20: 246–248.

    Article  CAS  Google Scholar 

  18. Fisher DA, Panos TC, Melby JC. Therapy of adrenocortical cancer with o,p’ DDD in two children.Cancer 1963; 23: 218–221.

    Google Scholar 

  19. Stewart DR, Morris-Jones PH, Jolley SA. Carcinoma of the adrenal gland in children.J Ped Surg 1974; 9: 59–67.

    Article  CAS  Google Scholar 

  20. Andler W, Havers W, Stambolis C, Medrano J, Stollmann B. Renal cell carcinoma following radiation therapy for an adrenocortical carcinoma.J Pediatr 1978; 93: 634–636.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to S. B. Bavdekar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bavdekar, S.B., Kasla, R.R., Parmar, R.C. et al. Selective testosterone secreting adrenocortical carcinoma in an infant. Indian J Pediatr 68, 95–97 (2001). https://doi.org/10.1007/BF02728872

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02728872

Key words

Navigation