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Supercritical carbon dioxide extraction of evening primrose oil

  • Published:
Journal of the American Oil Chemists’ Society

Abstract

The oil extracted from the seeds ofOenothera biennis L. (evening primrose) is a major commercial source of gamma-linolenic acid, a fatty acid having potential therapeutic value in the treatment of several diseases. This fatty acid is prone to oxidation and thermal rearrangement; therefore, the conventional recovery of the oil via mechanical expression and hexane extraction must be carried out under very mild and controlled conditions. In this study, supercritical fluid extraction with carbon dioxide has been employed as an alternative method to recover evening primrose oil (EPO). Extractions were performed over the pressure range of 20–70 MPa and at temperatures from 40 to 60°C, with a CO2 mass flow rate of 18 g/min. The experimental data permitted the determination of EPO solubility in supercritical CO2 at the tested extraction conditions. Supercritical fluid Chromatographic analysis of fractions collected during the extraction showed a subtle shift in the triglyceride composition. Fatty acid methyl ester analysis on similar fractions indicated that the fatty acid content was invariant with respect to extraction time.

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References

  1. Traitler, H., H. Winter, U. Richli and Y. Ingenbleek,Lipids 19:923 (1984).

    Article  CAS  Google Scholar 

  2. Helme, J.P.,Rev. Fr. Corps Gras 33:107 (1986).

    CAS  Google Scholar 

  3. Uzzan, A.,Ibid. 35:501 (1988).

    CAS  Google Scholar 

  4. Glen, E., L. MacDonnel, I. Glen and J. MacKenzie, inPhar- macological Treatments for Alcoholism, edited by G. Edwards and J. Littleton, Crooms-Helm, London, 1984, p. 331.

    Google Scholar 

  5. Puolakka, J., L. Makarainen, L. Viinikka and O. Ylikorkala,J. Reprod. Med. 30:149 (1985).

    CAS  Google Scholar 

  6. Belch, J.J.F., S. Ansell, R. Madhok, A. O’Dowd and R.D. Stur- rock,Ann. Rheumatic Dis. 47:96 (1988).

    Article  CAS  Google Scholar 

  7. Biagi, P.L., A. Bordoni, A. Masi, G. Ricci, C. Fanelli, A. Patrizi and E. Ceccolini,Drugs Exptl. Clin. Res. 14:285 (1988).

    CAS  Google Scholar 

  8. Carter, J.P.,Food Technol. 42:72 (1988).

    CAS  Google Scholar 

  9. Monnier, L., S. El Boustani, A. Crastes de Paulet, B. Descomps and F. Mendy,Rev. Fr. Corps Gras 36:3 (1989).

    CAS  Google Scholar 

  10. Bohannon, M.B., and R. Kleiman,Lipids 11:157 (1976).

    Article  CAS  Google Scholar 

  11. Wolf, R.B., R. Kleiman and R.E. England,J. Am. Oil Chem. Soc. 60:1858 (1983).

    Article  CAS  Google Scholar 

  12. Hudson, B.J.F.,Ibid. 61:540 (1984).

    CAS  Google Scholar 

  13. Bottazzi, F., R. Izzo and G. Lotti,Agrochimica 29:331 (1985).

    CAS  Google Scholar 

  14. Lawson, L.D., and B.G. Hughes,Lipids 23:313 (1988).

    Article  CAS  Google Scholar 

  15. Sakaki, K., Y. Yokoshi, O. Suzuki and T. Hakuta,J. Am. Oil Chem. Soc. 67:553 (1990).

    Article  CAS  Google Scholar 

  16. Paul, P.F.M., and W.S. Wise,The Principles of Gas Extraction, Mills & Boon, London, England, 1971.

    Google Scholar 

  17. Bott, T.R.,Chem. Ind. 15:288 (1980).

    Google Scholar 

  18. McHugh, M.A., and V.J. Krukonis,Supercritical Fluid Extrac- tion, Butterworths, Stoneham, MA, 1986.

    Google Scholar 

  19. Rizvi, S.S.H., J.A. Daniels, A.L. Benado and J.A. Zollweg,Food Téchnol. 40:57 (1986).

    Google Scholar 

  20. Stahl, E., K.W. Quirin and D. Gerard,Dense Gases for Extrac- tion and Refining, Springer-Verlag, New York, NY, 1988.

    Google Scholar 

  21. Zosel, K., U.S. Patent 4,247,570, (1981).

  22. Vollbrecht, R.,Chem. Ind. 12:391 (1982).

    Google Scholar 

  23. Friedrich, J.P., U.S. Patent 4,466,923, (1984).

  24. Favati, F., J.W. King, J.P. Friedrich and K. Eskins,J. Food Sci. 53:1532 (1988).

    Article  CAS  Google Scholar 

  25. Temelli, F., C.S. Chen and R.J. Braddock,Food Technol. 42:145 (1988).

    CAS  Google Scholar 

  26. Bradley, R.L.,J. Dairy Sci. 72:2834 (1989).

    Article  CAS  Google Scholar 

  27. Di Giovacchino, L., M. Solinas, V. Brandani, G. Del Re and G. Di Giacomo,Industrie Alimentari 28:925 (1989).

    Google Scholar 

  28. Quirin, K.W., D. Gerard and J. Kraus,Fat Sci. Technol. 89:139 (1987).

    CAS  Google Scholar 

  29. Tblboe, O., I.R. Hansen and V.K.S. Shukla, inProceedings of the First International Symposium on Supercritical Fluids, October 17-19, 1988, Nice, Franca

  30. Eggers, R., and U. Sievers, inSupercritical Fluid Science and Technology, ACS Symposium Series 406, edited by KP. Johnston and J.M.L. Penninger, ACS, Washington, D.C., 1989, p. 478.

    Google Scholar 

  31. Official and Tentative Methods of the American Oil Chemists’ Society, 3rd edn., American Oil Chemists’ Society, Champaign, IL, 1964 (revised to 1976).

  32. Ratnayake, W.M.N., D.G. Matthews and R.G. Ackman,J. Am. Oil Chem. Soc. 66:966 (1989).

    CAS  Google Scholar 

  33. Kennedy, G.C.,Am. J. Sci. 252:225 (1954).

    Article  CAS  Google Scholar 

  34. Friedrich, J.P., and E.H. Pryde,J. Am. Oil Chem. Soc. 61:223 (1984).

    CAS  Google Scholar 

  35. Quirin, K.W.,Fette Seifen Anstrichmittel 84:460 (1982).

    Article  CAS  Google Scholar 

  36. Stahl, E., K.W. Quirin and D. Gerard, Ibid. 85:458 (1983).

    Article  CAS  Google Scholar 

  37. Evelein, K.A., R.G. Moore and R. Heidemann,Ind. Eng. Chem. Process Des. Dev. 15:423 (1976).

    Article  CAS  Google Scholar 

  38. Dakovic, S., J. Turkulov and E. Dimic,Fat. Sci. Technol 91:116 (1989).

    CAS  Google Scholar 

  39. Eggers, R., and U. Sievers,J. Chem. Eng. of Japan 22:641 (1989).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Lstituto di Industrie Agrarie dell’Universita, Via S. Michele, 4, 56123, Pisa, Italy

    Fabio Favati

  2. Food Physical Chemistry Research, National Center for Agricultural Utilization Research, USDA, Agricultural Research Service, 61604, Peoria, IL

    Jerry W. King & Monica Mazzanti

Authors
  1. Fabio Favati
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  2. Jerry W. King
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  3. Monica Mazzanti
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The mention of firm names or trade products does not imply that they are endorsed or recommended by the U.S. Department of Agriculture over other firms or similar products not mentioned.

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Favati, F., King, J.W. & Mazzanti, M. Supercritical carbon dioxide extraction of evening primrose oil. J Am Oil Chem Soc 68, 422–427 (1991). https://doi.org/10.1007/BF02663760

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  • DOI: https://doi.org/10.1007/BF02663760

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