Abstract
We report a rare case of solitary fibrous tumor (SFT) of the meninges of the posterior fossa presenting as an intracerebellar hemorrhage. A 29-year-old woman was admitted with sudden-onset severe headache, nausea, and vomiting. A computed tomographic (CT) scan of the brain revealed an intracerebellar hemorrhage 3.5 cm in diameter. Gadolinium-enhanced magnetic resonance imaging (MRI) showed a heterogeneous enhancement mass. A posterior craniotomy found a firm, highly vascular tumor attached to the meninges. Histologically, the tumor showed mostly sclerotic tissues with spindle cells. In few areas, the tumor had a more compact arrangement of spindle-shaped cells with vascular spaces and highly cellular components. Immunohistochemical study revealed strong CD-34 immunopositivity in many tumor cells. The tumor was diagnosed as SFT of the meninges. We report the clinical and histological features of this newly described tumor with a heterogeneous component.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
El-Nagger A, Ward RM, Ro JY, et al (1987) Fibrous tumor with hemangiopericytitic pattern, so-called “localized fibrous tumor of pleura.” Lab Invest 56:21A
Hanau CA, Miettinen M, et al (1995) Solitary fibrous tumor: histological and immunohistochemical spectrum of benign and malignant variants presenting at different sites. Hum Pathol 26:440–449
Prayson R, McMahon JT, Barnett GH (1997) Solitary fibrous tumor of the meninges. Case report and review of the literature. J Neurosurg 86:1049–1052
Nikas DC, DeGirolami U, Folkerth RD, et al (1999) Parasagittal solitary fibrous tumor of the meninges. Case report and review of the literature. Acta Neurochirurgica 141:307–313
Carneiro SS, Scheithauer BW, Nascimento AG, et al (1996) Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. A clinicopathological and immunopathological study. Am J Clin Pathol 106:217–224
Challa VR, Kilpatrick SE, Ricci P, et al (1998) Solitary fibrous tumor of the meninges. Clin Neuropathol 17:73–78
Brunori A, Cerasoli S, Donati R, et al (1999) Solitary fibrous tumor of the meninges: two new cases and review of the literature. Surg Neurol 51:636–640
Ng H-K, Choi PCL, Wong C-W, et al (2000) Metastatic solitary fibrous tumor of the meninges. Case report. J Neurosurg 93:490–493
Chan JKC (1997) Solitary fibrous tumour—everywhere, and a diagnosis in vogue. Histopathology 31:568–576
Vallat-Decouvelaere AV, Dry SM, Fletcher CDM (1988) Atypical and malignant solitary fibrous tumors in extrathoracic tumors. Am J Surg Pathol 22:1501–1511
Stout AP, Murray MR (1942) Hemangiopericytoma: a vascular tumor featuring zimmerman's pericytes. Ann Surg 116:26–33
Goellner JR, Laws ER Jr, Soule EH, et al (1978) Hemangiopericytoma of the meninges: Mayo Clinic experience. Am J Clin Pathol 70:375–380
Guthrie BL, Ebersold MJ, Scheithauer BW, et al (1989) Meningeal hemangiopericytoma: histopathological features, treatment, and long-term follow-up of 44 cases. Neurosurgery 25:514–522
Mena H, Ribas JL, Paqueshkpour GH, et al (1991) Hemangiopericytoma of the central nervous system: a review of 94 cases. Hum Pathol 22:84–91
Perry A, Scheithauer BW, Nascimento AG (1977) The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. Am J Surg Pathol 21:1354–1360
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Sanno, N., Shimura, T., Macda, S. et al. A case of solitary fibrous tumor of the meninges. Brain Tumor Pathol 18, 43–47 (2001). https://doi.org/10.1007/BF02478924
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02478924