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Tailoring a commercial radioimmunoassay to the range of levels of progesterone occurring in human serum during controlled ovarian hyperstimulation and following embryo/gamete transfer

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Summary

While the Pantex direct P radioimmunoassay is used widely in programs of assisted conception, its sensitivity and range do not encompass the wide range of levels of P in serum of many patients during COH and through the first trimester of pregnancy. The present communication details minor modifications to the proprietary Pantex assay which accommodate these requirements. The nature of the changes does not compromise the performance characteristics or simplicity of the original assay and facilitates precise, accurate, and rapid measurement of serum P between 0.05 and 1280 ng/ml.

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References

  1. Arimura A, Talbot S, Serafini PC, Schally AV: Sites of paradoxical action of the LHRH agonist (D-Trp6)-LHRH. Int J Fertil 1980;25:151

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Authors and Affiliations

  1. Institute for Reproductive Research, 1245 Wilshire Boulevard, Suite 905, 90017, Los Angeles, California

    Bronte A. Stone, Kay Quinn, Patrick Quinn, Joyce M. Vargyas & Richard P. Marrs

Authors
  1. Bronte A. Stone
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  2. Kay Quinn
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  3. Patrick Quinn
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  4. Joyce M. Vargyas
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  5. Richard P. Marrs
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Stone, B.A., Quinn, K., Quinn, P. et al. Tailoring a commercial radioimmunoassay to the range of levels of progesterone occurring in human serum during controlled ovarian hyperstimulation and following embryo/gamete transfer. J Assist Reprod Genet 6, 257–260 (1989). https://doi.org/10.1007/BF01132874

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  • DOI: https://doi.org/10.1007/BF01132874

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