Abstract
Lysosomal enzyme activities in rabbit ocular tissues were examined at various times after the intravitreal injection of endotoxin. Lysosomal enzyme activities in the aqueous, vitreous, and pigment epithelium-choroid were elevated 3 h after injection. It is deduced from the fluorescein-labeled dextran and SDS-polyacrylamide gel electrophoresis analysis of the aqueous, vitreous, and pigment epithelium-choroid from endotoxin injected rabbits that the elevation of lysosomal enzyme activities are probably due to a breakdown in blood-ocular barriers.
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Tsung, P.K., Price, J. & Holly, F.J. Changes in lysosomal enzyme activities of eye tissues in endotoxin-induced inflammation. Inflammation 7, 257–267 (1983). https://doi.org/10.1007/BF00917263
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DOI: https://doi.org/10.1007/BF00917263