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Unbalanced 13q/21q translocation: A revised study of the case previously reported as 21-monosomy

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Summary

Reexamination was made on a male infant previously reported as 21-monosomy. Extensive chromosome banding analyses in the patient and parents disclosed an unbalanced de novo translocation between chromosomes 13 and 21. The patient's karyotype was interpreted as 45,XY,-13,-21,+der(13),t(13;21) (q2 or 3;q1 or 2)pat. The patient showed many clinical features characteristic of 13q- syndrome.

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Authors and Affiliations

  1. Chromosome Research Unit, Faculty of Science, Hokkaido University, 060, Sapporo

    Tatsuro Ikeuchi, Ikuko Kondo & Motomichi Sasaki

  2. Section of Hematology, Clinical Department, Saitama Cancer Center, Ina, 362, Saitama

    Yasuhiko Kaneko

  3. Kitami Red Cross Hospital, 090, Kitami, Japan

    Susumu Kodama & Tsukasa Hattori

Authors
  1. Tatsuro Ikeuchi
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  2. Ikuko Kondo
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  3. Motomichi Sasaki
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  4. Yasuhiko Kaneko
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  5. Susumu Kodama
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  6. Tsukasa Hattori
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Ikeuchi, T., Kondo, I., Sasaki, M. et al. Unbalanced 13q/21q translocation: A revised study of the case previously reported as 21-monosomy. Hum Genet 33, 327–330 (1976). https://doi.org/10.1007/BF00286861

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  • DOI: https://doi.org/10.1007/BF00286861

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