Glandular Neoplasia of the Uterine Cervix and Its Related Lesions

Parra-Herran, Carlos

doi:10.1007/978-981-13-3016-2_13

Carlos Parra-Herran^6,7

1392 Accesses
1 Citations

Abstract

This chapter describes the pathology of glandular neoplasia of the uterine cervix. The spectrum of endocervical glandular malignancy is wide and sometimes diagnostically challenging. While most cervical adenocarcinomas are secondary to Human Papillomavirus infection, some tumors are unrelated to it; these lesions are now recognized for their aggressive clinical behavior and still obscure pathogenesis. The description of each adenocarcinoma type in this chapter follows an etiology (HPV-related versus unrelated) and traditional morphology-based approach. Important diagnostic situations such as diagnosis of stromal invasion, pattern-based assessment, and staging are also discussed. The chapter also presents the pathology of mixed lesions with a glandular component and benign glandular proliferations that need to be distinguished from preinvasive and invasive endocervical malignancy.

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Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
Carlos Parra-Herran
Sunnybrook Health Sciences Centre, Toronto, ON, Canada
Carlos Parra-Herran

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Department of Pathology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA
Wenxin Zheng
Department of Pathology, University of California San Diego, San Diego, CA, USA
Oluwole Fadare
Department of Pathology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA
Charles Matthew Quick
Department of Pathology, Peking University People’s Hospital, Beijing, China
Danhua Shen
Department of Obstetrics and Gynecology, Tianjin Gynecologic and Obstetrics Central Hospital, Tianjin, China
Donghui Guo

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Parra-Herran, C. (2019). Glandular Neoplasia of the Uterine Cervix and Its Related Lesions. In: Zheng, W., Fadare, O., Quick, C., Shen, D., Guo, D. (eds) Gynecologic and Obstetric Pathology, Volume 1. Springer, Singapore. https://doi.org/10.1007/978-981-13-3016-2_13

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DOI: https://doi.org/10.1007/978-981-13-3016-2_13
Published: 04 July 2019
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Glandular Neoplasia of the Uterine Cervix and Its Related Lesions