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Omics Approaches: A Useful Tool in Asthma Precision Medicine

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Genomic Approach to Asthma

Part of the book series: Translational Bioinformatics ((TRBIO,volume 12))

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Abstract

Asthma is a complex and heterogeneous disease. Various symptoms, underlying pathogenetic mechanisms, different responses to medication and prognosis are unmet need in clinic. This volume aims to elucidate how the “-omics” research applied in asthma such as “genomic, transcriptomic, proteomic, metabomic, et al” progresses and present the related series of important breakthroughs in asthma development, classification, prevention and drug sensitivity. Systemic biology, computational model and biostatistical database are discussed regarding big data storage, management and interpretation. Applying unbiased -omics combined with hypothesis-driven approach is one way to push forward our understanding of endotype of asthma and transform the current medication mode to a more précised one.

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Author information

Authors and Affiliations

  1. Shanghai Respiratory Research Institute, Respiratory Division of Zhongshan Hospital, Fudan University, Shanghai, China

    Zhihong Chen

  2. Zhongshan Hospital Institute of Clinical Science, Shanghai Medical School, Fudan University, Shanghai, China

    Xiangdong Wang

  3. Shanghai Institute of Clinical Bioinformatics, Fudan University, Shanghai, China

    Xiangdong Wang

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  1. Zhihong Chen
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Correspondence to Xiangdong Wang .

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Editors and Affiliations

  1. Zhongshan Hospital Institute of Clinical Science, Shanghai Medical School Fudan University, Shanghai, China

    Xiangdong Wang

  2. Shanghai Respiratory Research Institute, Respiratory Division of Zhongshan Hospital, Fudan University, Shanghai, China

    Zhihong Chen

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Chen, Z., Wang, X. (2018). Omics Approaches: A Useful Tool in Asthma Precision Medicine. In: Wang, X., Chen, Z. (eds) Genomic Approach to Asthma. Translational Bioinformatics, vol 12. Springer, Singapore. https://doi.org/10.1007/978-981-10-8764-6_1

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