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Ventricular Tachycardia in Non-ischemic Cardiomyopathy

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Catheter Ablation
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Abstract

Non-ischemic cardiomyopathy is defined as a cardiomyopathy characterized by mechanical dysfunction in the absence of significant coronary artery disease. This category contains various kinds of heart disease. Patients with non-ischemic cardiomyopathy sometimes present lethal ventricular arrhythmias such as ventricular tachycardia (VT) and ventricular fibrillation. According to guidelines, the first-line therapy for non-ischemic VT is optimization of the ICD programming and antiarrhythmic drugs. However, ventricular tachyarrhythmias cannot be prevented by the ICD itself. The mechanism of non-ischemic VTs is mainly reentry. Therefore, the same mapping and ablation techniques using 3D mapping system for past-infarction VT can be applied. Catheter ablation is also highly effective in patients with non-ischemic VT as post-infarction VT.

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References

  1. Pedersen CT, Kay GN, Kalman J, et al. EHRA/HRS/APHRS expert consensus on ventricular arrhythmias. Europace. 2014;16:1267–83.

    Google Scholar 

  2. Hsia HH, Marchlinski FE. Characterization of the electroanatomic substrate for monomorphic ventricular tachycardia in patients with nonischemic cardiomyopathy. Pacing Clin Electrophysiol. 2002;25:1114–27.

    Article  PubMed  Google Scholar 

  3. Pogwizd SM, McKenzie JP, Cain ME. Mechanisms underlying spontaneous and induced ventricular arrhythmias in patients with idiopathic dilated cardiomyopathy. Circulation. 1998;98:2404–14.

    Article  CAS  PubMed  Google Scholar 

  4. de Bakker JM, van Capelle FJ, Janse MJ, et al. Slow conduction in the infarcted human heart. ‘Zigzag’ course of activation. Circulation. 1993;88:915–26.

    Article  PubMed  Google Scholar 

  5. Soejima K, Stevenson WG, Sapp JL, et al. Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with dilated cardiomyopathy. The importance of low-voltage scars. J Am Coll Cardiol. 2004;43:1834–42.

    Article  PubMed  Google Scholar 

  6. Oloriz T, Silberbauer J, Maccabelli G, et al. Catehter ablation of ventricular arrhythmia in nonischemic cardiomyopathy. Anterosptal versus inferolateral scar sub-types. Circ Arrhythm Electrophysiol. 2014;7:414–23.

    Article  PubMed  Google Scholar 

  7. Gokoglan Y, Mohanty S, Gianni C, et al. Scar homogenization versus limited-substrate ablation in patients with nonischemic cardiomyopathy and ventricular tachycardia. J Am Coll Cardiol. 2016;68:1990–8.

    Article  PubMed  Google Scholar 

  8. Zeppenfeld K, Schalij MJ, Bartelings MM, et al. Catheter ablation of ventricular tachycardia after repair of congenital heart disease: electroanatomic identification of the critical right ventricular isthmus. Circulation. 2007;116:2241–52.

    Article  CAS  PubMed  Google Scholar 

  9. Kriebel T, Saul JP, Schneider H, Sigler M, Paul T. Noncontact mapping and radiofrequency catheter ablation of fast and hemodynamically unstable ventricular tachycardia after surgical repair of tetralogy of Fallot. J Am Coll Cardiol. 2007;50:2162–8.

    Article  PubMed  Google Scholar 

  10. Fedgchin B, Pavri BB, Greenspon AJ, Ho RT. Unique self-perpetuating cycle of atrioventricular block and phase IV bundle branch block in a patient with bundle branch reentrant tachycardia. Heart Rhythm. 2004;1:493–6.

    Article  PubMed  Google Scholar 

  11. Lewalter T, Jung W, Preusse CJ, Lickfett L, Wolpert C, Yang A, Welz A, Luderitz B. Radiofrequency catheter ablation of an incessant ventricular tachycardia following valve surgery. Pacing Clin Electrophysiol. 2002;25:105–8.

    Article  PubMed  Google Scholar 

  12. Eckart RE, Hruczkowski TW, Tedrow UBZ, Koplan ZBA, Epstein LM, Stevenson WG. Sustained ventricular tachycardia associated with correctrive valve surgery. Circulation. 2007;116:2005–11.

    Article  PubMed  Google Scholar 

  13. Mazzanti A, Ng K, Faragli A, Maragna R, Chiodaroli E, et al. Arrhythmogenic right ventricular cardiomyopathy. Clinical course and predictors of arrhythmic risk. J Am Coll Cardiol. 2016;68:2540–50.

    Article  PubMed  Google Scholar 

  14. Kies P, Bootsma M, Bax J, Schalij MJ, van der Wall EE. Arrhythmogenic right ventricular dysplasia/cardiomyopathy: screening, diagnosis, and treatment. Heart Rhythm. 2006;3:225–34.

    Article  PubMed  Google Scholar 

  15. Liuba I, Marchlinski FE. The substrate and ablation of ventricular tachycardia in patients with nonischemic cardiomyopathy. Circ J. 2013;77:1957–66.

    Article  PubMed  Google Scholar 

  16. Marra MP, Leoni L, Bauce B, Corbetti F, Zorzi A, Migliore F, et al. Imaging study of ventricular scar in arrhythmogenic right ventricular cardiomyopathy: comparison of 3D standard electroanatomical voltage mapping and contrast-enhanced cardiac magnetic resonance. Circ Arrhythm Electrophysiol. 2012;5:91–100.

    Article  PubMed  Google Scholar 

  17. Bai R, Di Biase L, Shivkumar K, et al. Ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy arrhythmia-free survival after endo-epicardial substrate based mapping and ablation. Circ Arrhythm Electrophysiol. 2011;4:478–85.

    Article  PubMed  Google Scholar 

  18. Berruezo A, Fern’andez-Armenta J, Mont L, et al. Combined endocardial and epicardial catheter ablation in arrhythmogenic right ventricular dysplasia incorporating scar dechanneling technique. Circ Arrhythm Electrophysiol. 2012;5:111–21.

    Article  PubMed  Google Scholar 

  19. Philips B, Madhavan S, James C, et al. High prevalence of catecholamine-facilitated focal ventricular tachycardia in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Arrhythm Electrophysiol. 2013;6(1):160–6.

    Article  CAS  PubMed  Google Scholar 

  20. Birnie DH, Sauer WH, Bogun F, Cooper JM, Culver DA, et al. HRS expert consensus statement on the diagnosis ans management of arrhythmias associated with cardiac sarcoidosis. Heart Rhythm. 2014;11(7):1304–23.

    Article  Google Scholar 

  21. Naruse Y, Sekiguchi Y, Nogami A, Okada H, Yamauchi Y, et al. Systemic treatment approach to ventricular tachycardia in cardiac sarcoidosis. Circ Arrhythm Electrophysiol. 2014;7:407–13.

    Article  PubMed  Google Scholar 

  22. Jefic D, Joel B, Good E, et al. Role of radiofrequency catheter ablation of ventricular tachycardia in cardiac sarcoidosis: report from a multicenter registry. Heart Rhythm. 2009;6:189–95.

    Article  PubMed  Google Scholar 

  23. Koplan BA, Soejima K, Baughman K, Epstein LM, Stevenson WG. Refractory ventricular tachycardia secondary to cardiac sarcoid: electrophysiologic characteristics, mapping, and ablation. Heart Rhythm. 2006;3:924–9.

    Article  PubMed  Google Scholar 

  24. Kumar S, Barbhaiya C, Nagashima K, Choi EK, Epstein LM, et al. Ventricular tachycardia in cardiac sarcoidosis. Characterization of ventricular substrate and outcomes of catheter ablation. Circ Arrhythm Electrophysiol. 2015;8:87–93.

    Article  PubMed  Google Scholar 

  25. Muser D, Santangeli P, Pathak RK, Castro SA, Liang JJ, et al. Long-term outcomes of catheter ablation of ventricular tachycardia in patients with cardiac sarcoidosis. Circ Arrhythm Electrophysiol. 2016;9:e004333. https://doi.org/10.1161/CIRCEP.111.004333.

    Article  PubMed  Google Scholar 

  26. Sacher F, Tedrow UB, Field ME, et al. Ventricular tachycardia ablation: evolution of patients and procedures over 8 years. Circ Arrhythm Electrophysiol. 2008;1:153–61.

    Article  PubMed  Google Scholar 

  27. Tokuda M, Tedrow UB, Kojodjojo P, et al. Catheter ablation of ventricular tachycardia in nonischemic heart disease. Circ Arrhythm Electrophysiol. 2012;5:992–1000.

    Article  PubMed  Google Scholar 

  28. Goya M, Fukunaga M, Hiroshima K, Hayashi K, Makihara Y, et al. Long-term outcomes of catheter ablation of ventricular tachycardia in patients with structural heart disease. J Arrhythm. 2015;31(1):22–8.

    Article  PubMed  Google Scholar 

  29. Kumar S, Romero J, Mehta N, Fujii A, Kapur S, et al. Long-term outcome after catheter ablation of ventricular tachycardia in patients with and without structural heart disease. Heart Rhythm. 2016;13:1957–63.

    Article  PubMed  Google Scholar 

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Correspondence to Masahiko Goya .

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Goya, M. (2018). Ventricular Tachycardia in Non-ischemic Cardiomyopathy. In: Hirao, K. (eds) Catheter Ablation. Springer, Singapore. https://doi.org/10.1007/978-981-10-4463-2_35

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  • DOI: https://doi.org/10.1007/978-981-10-4463-2_35

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  • Print ISBN: 978-981-10-4462-5

  • Online ISBN: 978-981-10-4463-2

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