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Neurourology pp 27–36Cite as

Peripheral Neural Control of the Lower Urinary Tract

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Abstract

Storage and elimination of urine are dependent upon the coordinated activity of two functional units in the lower urinary tract; the urinary bladder and its outlet, which are innervated by three sets of peripheral nerves: sacral parasympathetic (pelvic nerves), thoracolumbar sympathetic (hypogastric nerves and sympathetic chain) and sacral somatic nerves (pudendal nerves). The efferent neurotransmission is modulated by cholinergic, adrenergic, and non-cholinergic and non-adrenergic mechanisms. The Pelvic nerve afferents monitor the volume of the bladder and the amplitude of the bladder contraction. The afferent signalling is modulated by a varity of receptors and transmitters including ATP, nitric oxides, P2X3 receptors, TRP cation channels, and Cannabinoids.

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Authors and Affiliations

  1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, Tokyo, Japan

    Yasuhiko Igawa

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  1. Yasuhiko Igawa
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Correspondence to Yasuhiko Igawa .

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  1. Department of Urology, China Rehabiliation Research Center Capital Medical University, Beijing, China

    Limin Liao

  2. Department of Urology, University Hospital, Innsbruck, Austria

    Helmut Madersbacher

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Igawa, Y. (2019). Peripheral Neural Control of the Lower Urinary Tract. In: Liao, L., Madersbacher, H. (eds) Neurourology. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7509-0_3

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