Abstract
Early diagnosis and treatment of cancer have long been established as basic principles of modern surgical oncology. There is no doubt that a better understanding of the pathobiological features of small hepatocellular carcinoma (SHCC) will provide clinicians with the pathobiological basis to better treat these tumors and to improve long-term survivals of patients. For relatively small HCC, several designations such as “early HCC” and “subclinical HCC” [1] have been proposed. The definitions of these tumors are based mainly upon tumor size, and each definition uses a different size. The concept of SHCC can be traced back to the late 1970s [2, 3], when SHCC was considered as the most significant prognostic factor of long-term survival.
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Cong, W., Lu, X., Lau, W. (2016). Pathobiologic Characteristics of Small Hepatocellular Carcinoma. In: Chen, M., Zhang, Y., Lau, W. (eds) Radiofrequency Ablation for Small Hepatocellular Carcinoma. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7258-7_2
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