Skip to main content

Cerebral Edema Due to Cerebral Infarction in the Gerbil

  • Chapter
  • 16 Accesses

Abstract

The Mongolian garbil (Meriones unguiculatus) has an incomplete circle of Willis, lacking a major posterior communicating artery (7). Unilateral ligation of the common carotid artery in the neck under barbiturate anesthesia produces cerebral infarction in approximately 80% of animals. Neurological deficit and death follows in 80% of those sustaining an infarct.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Amos III, A., Wright, R. L., Kowada, M., Thurston, J. M., and Majrio, G.: “Cerebral ischaemia. II. The no flow phenomenon.” Am. J. Path. 52:437–453 (1968).

    Google Scholar 

  2. Brock, M., Beck, J., Markabis, E., and Dietz, H.: “Intracranial pressure gradients associated with experimental cerebral embolism.” Stroke 3:123–130 (1972).

    Article  PubMed  CAS  Google Scholar 

  3. Elliott, K. A. C., and Jasper, H. H.: “Measurement of experimentally induced brain swelling and shrinkage.” Am. J. Physiol. 157:122–129 (1949).

    PubMed  CAS  Google Scholar 

  4. Fischer, E. G., and Ames III, A..: “Studies of impairment of cerebral circulation following ischaemia: Effect of haemodilution and perfusion pressure.” Stroke 3:538–542 (1972).

    Article  PubMed  CAS  Google Scholar 

  5. Harrison, M. J. G., and Ross Russell, R. W.: “Effect of dexamethasone on cerebral infarction in the gerbil.” J. Neurol. Neurosurg. Psychiat. 35:520–521 (1972).

    Article  PubMed  CAS  Google Scholar 

  6. Harrison, M. J. G., Brownbill, D., Lewis, P. D., and Ross Russell, R. W.: “Cerebral oedema following carotid artery ligation in the gerbil.” Arch. Neurol. (in press).

    Google Scholar 

  7. Levine, S., and Sohn, D.: “Cerebral ischaemia in infant and adult gerbils.” Arch. Path. 87:315–317 (1969).

    PubMed  CAS  Google Scholar 

  8. Reivich, M., Jehle, J., Sokoloff, L., and Kety, S. S.: “Measurement of regional cerebral blood flow with antipyrine-14C in awake cats.” J. Appl. Physiol. 27:296–300 (1969).

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1975 Springer-Verlag New York Inc.

About this chapter

Cite this chapter

Harrison, M.J.G., Ross Russell, R.W. (1975). Cerebral Edema Due to Cerebral Infarction in the Gerbil. In: Langfitt, T.W., McHenry, L.C., Reivich, M., Wollman, H. (eds) Cerebral Circulation and Metabolism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65814-3_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-65814-3_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65816-7

  • Online ISBN: 978-3-642-65814-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics