Abstract
Based on three classifications of the DNA bases, three 2-D graphical representations of DNA primary sequences were proposed. These are called R/Y-ratio curve, M/K-ratio curve and W/S-ratio curve, respectively. The presented method has the advantages that (a) there is no loss of information when transferring a DNA sequence to its mathematical representation; and (b) the coordinates of every node on the three 2-D curves have clear biological implication. As an example, the similarities among the coding sequences of the first exon of beta-globin gene from eight species were examined.
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Yu, HJ. (2012). Similarity Analysis of DNA Sequences Based on Three 2-D Cumulative Ratio Curves. In: Huang, DS., Gan, Y., Premaratne, P., Han, K. (eds) Bio-Inspired Computing and Applications. ICIC 2011. Lecture Notes in Computer Science(), vol 6840. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24553-4_61
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DOI: https://doi.org/10.1007/978-3-642-24553-4_61
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-24552-7
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