Abstract
Understanding the nature of rectal cancer is a dynamic process. The significance of imaging in relation to the interaction of treatment and individual prognosis is constantly evolving. Although specialized rectal cancer surgery offers the most probable chance of cure, the contribution of neoadjuvant chemoradiation to the reduction of local recurrence rates and improved patient survival is increasingly realized. To this end, magnetic resonance imaging (MRI) is frequently used to select patients for neoadjuvant chemoradiation and to predict a tumor-free circumferential resection plane at surgery. Current state-of-the-art pelvic MRI consistently depicts the mesorectal fascia. By definition, if a tumor lies within 1 mm of this fascia, then the surgical resection margin is deemed to be involved. Hence, MRI strongly supports the identification of patients who are at high risk of oncologically incomplete resection. Selecting these patients prior to surgery allows for the addition of preoperative chemoradiation therapy (Koh et al. 2006). MRI for rectal cancer has emerged as the first-line imaging tool for multidisciplinary team (MDT) decisions. The adoption of new concepts such as moving-table MRI for the assessment of metastatic spread and diffusion-weighted imaging (DWI) will further strengthen the role of MRI as a “one-stop-shop” staging procedure. Although MRI can provide a broad overview of the extent of the disease, but it may also make diagnosis more complex. A radiologist who specializes in pelvic MRI must be familiar with the principles of recent imaging techniques, as well as with characteristic imaging findings associated with rectal cancer. This chapter provides a summary of current clinical practice regarding pelvic MRI at 1.5 T for staging of rectal cancer.
Keywords
- Rectal Cancer
- Apparent Diffusion Coefficient
- Circumferential Resection Margin
- Mucinous Adenocarcinoma
- Pelvic Magnetic Resonance Imaging
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Abel ME, Chiu YS, Russel TR et al (1993) Adenocarcinoma of the anal glands: results of a survey. Dis Colon Rectum 36:383–387
Abir F, Alva S, Longo WE et al (2006) The postoperative surveillance of patients with colon cancer and rectal cancer. Am J Surg 192:100–108
Abulafi AM, Williams NS (1994) Local recurrence of colorectal cancer: the problem, mechanisms, management and adjuvant therapy. Br J Surg 81:7–19
Adam IJ, Mohamdee MO, Martin IG et al (1994) Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 344:707–711
Akasu T, Iinuma G, Fujita T et al (2005) Thin-section MRI with a phased-array coil for preoperative evaluation of pelvic anatomy and tumor extent in patients with rectal cancer. AJR Am J Roentgenol 184:531–538
Alexander RM, Kaminsky DB (1979) Giant conyloma acuminatum (Buschke-Loewenstein tumor) of the anus. Case report and review of the literature. Dis Colon Rectum 22:561–565
Allen SD, Padhani AR, Dzik-Jurasz AS et al (2007) Rectal carcinoma: MRI with histologic correlation before and after chemoradiation therapy. AJR Am J Roentgenol 188:442–451
Almagro UA (1983) Primary signet-ring carcinoma of the colon. Cancer 52:1453–1457
Andea AA, Klimstra DS (2005) Adenocarcinoma arising in a tailgut cyst with prominent meningothelial proliferation and thyroid tissue: case report and review of the literature. Virchows Arch 446:316–321
Andreola S, Leo E, Belli F et al (1996) Manual dissection of adenocarcinoma of the lower third of the rectum specimens for detection of lymph node metastases smaller than 5 mm. Cancer 77:607–612
Arriola E, Navarro M, Pares D et al (2006) Imaging techniques contribute to increased surgical rescue of relapse in the follow-up of colorectal cancer. Dis Colon Rectum 49:478–484
Baik SH, Kim NK, Lee CH et al (2007) Gastrointestinal stromal tumor of the rectum: an analysis of seven cases. Surg Today 37:455–459
Balthazar EJ, Streiter M, Megibow AJ (1984) Anorectal giant condyloma acuminatum (Buschke-Loewenstein tumor): CT and radiographic manifestations. Radiology 150:651–653
Barkhausen J, Quick HH, Lauenstein T (2001) Whole-body MR imaging in 30 seconds with real-time true FISP and a continuously rolling table platform: feasibility study. Radiology 220:252–256
Barrett MW (1998) Chemoradiation for rectal cancer: current methods. Semin Surg Oncol 15:114–119
Bartelink H, Roelofsen F, Eschwege F et al (1997) Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European organization for research and treatment of cancer radiotherapy and gastrointestinal cooperative groups. J Clin Oncol 15:2040–2049
Baumann T, Ludwig U, Pache G et al (2008) Detection of pulmonary nodules with move-during-scan magnetic resonance imaging using a free-breathing turbo inversion recovery magnitude sequence. Invest Radiol 43:359–367
Baumann T, Ludwig U, Pache G et al (2009) Continuously moving table MRI with sliding multislice for rectal cancer staging: image quality and lesion detection. Eur J Radiol [ahead of print]
Beets-Tan RG, Beets GL (2004) Rectal cancer: review with emphasis on MR imaging. Radiology 232:335–346
Beets-Tan RG, Beets GL, Borstlap AC et al (2000) Preoperative assessment of local tumor extent in advanced rectal cancer: CT or high resolution MRI. Abdom Imaging 25:533–541
Beets-Tan RG, Beets GL, Vliegen RF et al (2001) Accuracy of magnetic resonance imaging in prediction of tumor-free resection margin in rectal cancer surgery. Lancet 357:497–504
Bhattacharjya S, Bhattacharjya T, Baber S et al (2004) Prospective study of contrast-enhanced computed tomography, computed tomography during arterioportography, and magnetic resonance imaging for staging of colorectal liver metastases for liver resection. Br J Surg 91:1361–1369
Billingham RP (1994) Extended lymphadenectomy for rectal cancer: cure vs quality of life. Int Surg 79:11–22
Bipat S, van Leeuwen MS, Comans EFI et al (2005) Colorectal liver metastases: CT, MR imaging, and PET for diagnosis – meta-analysis. Radiology 237:123–131
Birbeck KF, Macklin CP, Tiffin NJ et al (2002) Rates of circumferential resection margin involvement vary between surgeons and predict outcomes in rectal cancer surgery. Ann Surg 235:449–457
Blomqvist L, Holm T, Goranson H et al (1996) MR imaging, CT and CEA scintigraphy in diagnosis of local recurrence of rectal cancer. Acta Radiol 37:779–784
Blomqvist L, Holm T, Rubio C et al (1997) Rectal tumours: MR imaging with and/or phased-array coils, and histopathological staging on giant sections – a comparative study. Acta Radiol 38:437–444
Blomqvist L, Machado M, Rubio C et al (2000) Rectal tumor staging: MR imaging using pelvic phased-array and endorectal coils vs endoscopic ultrasonography. Eur Radiol 10:653–660
Bokey EL, Chapuis PH, Dent OF et al (1997) Factors affecting survival after excision of the rectum for cancer: a multivariate analysis. Dis Colon Rectum 40:3–10
Börnert P, Aldefeld B (2008) Principles of whole-body continuously-moving-table MRI. J Magn Reson Imaging 28:1–12
Brenner B, Tang LH, Klimstra DS et al (2004) Small-cell carcinomas of the gastrointestinal tract: a review. J Clin Oncol 22:2730–2739
Brown G (2005) Thin section MRI in multidisciplinary pre-operative decision making for patients with rectal cancer. Br J Radiol 78:117–127
Brown G, Davies S, Williams GT et al (2004) Effectiveness of preoperative staging in rectal cancer: digital rectal examination, endoluminal ultrasound or magnetic resonance imaging? Br J Cancer 91:23–29
Brown G, Radcliffe AG, Newcombe RG et al (2003a) Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging. Br J Surg 90:355–364
Brown G, Richards CJ, Bourne MW et al (2003b) Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison. Radiology 227:371–377
Brown G, Richards CJ, Newcombe RG et al (1999) Rectal carcinoma: thin-section MR imaging for staging in 28 patients. Radiology 211:215–222
Burdy G, Panis Y, Alves A et al (2001) Identifying patients with T3-T4 node-negative colon cancer at high risk of recurrence. Dis Colon Rectum 44:1682–1688
Burton S, Brown G, Daniels I et al (2006) MRI directed multidisciplinary team preoperative treatment strategy: the way to eliminate positive circumferential margins? Br J Cancer 94:351–357
Busse PM, Ng A, Recht A (1998) Induction therapy for rectal carcinoma. Semin Surg Oncol 15:120–125
Camilleri-Brennan J, Steele RJ (2001) The impact of recurrent rectal cancer on the quality of life. Eur J Surg Oncol 27:349–353
Carr I (1983) Lymphatic metastasis. Cancer Metastasis Rev 2:307–317
Cawthorn SJ, Parums DV, Gibbs NM et al (1990) Extent of mesorectal spread and involvement of lateral resection margin as prognostic factors after surgery of rectal cancer. Lancet 335:1055–1059
Cervantes A, Rodriguez-Braun E, Navarro S et al (2007) Integrative decisions in rectal cancer. Ann Oncol 18:127–131
Chauveinc L, Buthaut X, Falcou MC et al (2003) Anal cancer treatment: practical limitations of routine prescription of concurrent chemotherapy and radiotherapy. Br J Cancer 89:2057–2061
Chen CC, Lee RC, Lin JK et al (2005) How accurate is magnetic resonance imaging in restaging rectal cancer in patients receiving preoperative combined chemoradiotherapy? Dis Colon Rectum 48:722–728
Chung CK, Stryker JA, Demuth WE (1983) Patterns of failure following surgery alone for colorectal carcinoma. J Surg Oncol 22:65–70
Cody HS 3rd, Marcove RC, Quan SH (1981) Malignant retrorectal tumors: 28 years’ experience at Memorial Sloan-Kettering Cancer Center. Dis Colon Rectum 24:501–506
Colquhoun P, Wexner SD, Cohen A (2003) Adjuvant therapy is valuable in the treatment of rectal cancer despite total mesorectal excision. J Surg Oncol 83:135–139
Conlon KC, Casper ES, Brennan MF (1995) Primary gastrointestinal sarcomas: analysis of prognostic variables. Ann Surg Oncol 2:26–31
Connell WR, Sheffield JP, Kamm MA et al (1994) Lower gastrointestinal malignancy in Crohn’s disease. Gut 35:347–352
de Haas-Kock DF, Baeten CG, Jager JJ et al (1996) Prognostic significance of radial margins of clearance in rectal cancer. Br J Surg 83:781–785
Delany CP, Lavery IC, Brenner A et al (2002) Preoperative radiotherapy improves survival for patients undergoing total mesorectal excision for stage T3 low rectal cancers. Ann Surg 236:203–207
DeMatteo RP, Lewis JJ, Leung D et al (2000) Two hundred gastrointestinal tumors: recurrence patterns and prognostic factors for survival. Ann Surg 231:51–58
Desch CE, Benson AB, Somerfield MR et al (2005) Colorectal cancer surveillance: 2005 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol 23:8512–8519
DeVries AF, Kremser C, Hein PA et al (2003) Tumor microcirculation and diffusion predict therapy outcome for primary rectal carcinoma. Int J Radiat Oncol Biol Phys 56:958–965
Dicle O, Obuz F, Cakmakci H (1999) Differentiation of recurrent rectal cancer and scarring with dynamic MR imaging. Br J Radiol 72:1155–1159
Dixon WT, Brummer ME, Malko JA (1988) Acquisition order and motional artifact reduction in spin warp images. Magn Reson Med 6:74–83
Dworak O (1991) Morphology of lymph nodes in the resected rectum of patients with rectal carcinoma. Pathol Res Pract 187:1020–1024
Dworak O, Keilholz L, Hoffmann A (1997) Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis 12:19–23
Dzik-Jurasz A, Domenig C, George M et al (2002) Diffusion MRI for prediction of response of rectal cancer to chemoradiation. Lancet 360:307–308
Enker WE, Thaler HT, Cranor ML et al (1995) Total mesorectal excision in the operative treatment of carcinoma of the rectum. J Am Coll Surg 181:335–346
Eriksen MT, Wibe A, Haffner J et al (2007) Prognostic groups in 1,676 patients with T3 rectal cancer treated without preoperative radiotherapy. Dis Colon Rectum 50:1–11
Fain SB, Browning FJ, Polzin JA et al (2004) Floating table isoropic projection (FLIPR) acquisition: a time-resolved 3D method for extended field-of-view MRI during continuous table motion. Magn Reson Med 52:1093–1102
Fautz HP, Honal M, Saueressig U et al (2007) Artifact reduction in moving-table acquisitions using parallel imaging and multiple averages. Magn Reson Med 57:226–232
Fautz HP, Kannengiesser SAR (2006) Sliding Multislice (SMS): a technique for minimum FOV usage in axial continuously moving-table acquisitions. Magn Reson Med 55:363–370
Figueredo A, Rumble RB, Maroun J et al (2003) Follow-up of patients with curatively resected colorectal cancer: a practice guideline. BMC Cancer 3:26
Fletcher CD, Berman JJ, Corless C et al (2002) Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 33:459–465
Freier DT, Stanley JC, Thomson NW (1971) Retrorectal tumors in adults. Surg Gynecol Obstet 132:681–686
Frija G, Clement O, Le Guen O et al (1996) Experimental investigation of the delivery pathway of ultrasmall superparamagnetic iron oxide to lymph nodes. Acta Radiol 3:299–300
Fujita S, Nakanisi Y, Taniguchi H et al (2007) Cancer invasion to Auerbach’s plexus is an important prognostic factor in patients with pT3-pT4 colorectal cancer. Dis Colon Rectum 50:1860–1866
Gaertner WB, Hagerman GF, Finne CO et al (2008) Fistula-associated anal adenocarcinoma: good results with aggressive therapy. Dis Colon Rectum 51:1061–1067
Gaffey MJ, Mills SE, Lack EE (1990) Neuroendocrine carcinoma of the colon and rectum – a clinicopathologic, ultrastructural and immunohistochemical study of 24 cases. Am J Surg Pathol 14:1010–1023
Gagliardi G, Bayar S, Smith R et al (2002) Preoperative staging of rectal cancer using magnetic resonance imaging with external phased-array coils. Arch Surg 137:437–444
Getz SB Jr, Ough YD, Patterson RB et al (1981) Mucinous adenocarcinoma developing in chronic anal fistula: report of two cases and review of the literature. Dis Colon Rectum 24:562–566
Giordano P, Efron J, Vernava AM et al (2006) Strategies of follow-up for colorectal cancer: a survey of the American Society of Colon and Rectal Surgeons. Tech Coloproctol 10:199–207
Goh JS, Goh JP, Wansaicheong GK (2002). Methylcellulose as a rectal cotrast agent for MR imaging of rectal carcinoma. AJR Am J Roentgenol 178:1145–1146
Goldberg RM, Fleming TR, Tangen CM et al (1998) Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Eastern cooperative oncology group, the North central cancer treatment group, and the Southwest oncology group. Ann Intern Med 129:27–35
Goldstein NS, Long A, Kuan SF et al (2000) Colon signet ring cell adenocarcinoma: immunohistochemical characterization and comparison with gastric and typical colon adenocarcinoma. Appl Immunohistochem Mol Morphol8:183–188
Gosens MJ, Van Krieken JH, Marijnen CA et al (2007) Improvement of staging by combining tumor and treatment parameters: the value of prognostication in rectal cancer. Clin Gastroenterol Hepatol 5:997–1003
Govindarajan A, Coburn N, Kiss A et al (2006) Population based assessment of the surgical management of locally advanced rectal cancer. J Natl Cancer Inst 98:1474–1481
Grann A, Minsky BD, Cohen AM et al (1997) Preliminary results of preoperative 5-fluorouracil, low-dose leucovorin, and concurrent radiation therapy for clinically resectable T3 rectal cancer. Dis Colon Rectum 40:512–522
Griswold MA, Jakob PM, Heidemann RM et al (2002) Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 47:1202–1210
Grubnic S, Vinniecombe SJ, Norman AR et al (2002) MR evaluation of normal retroperitoneal and pelvic lymph nodes. Clin Radiol 57:193–200
Guerra A, Borda F, Javier Jimenez F et al (1998) Multivariate analysis of prognostic factors in resected colorectal cancer: a new prognostic index. Eur J Gastroenterol Hepatol 10:51–58
Guillem JG, Chessin DB, Cohen AM et al (2005) Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer. Ann Surg 241:829–838
Guillem JG, Diaz-Gonzalez JA, Minsky BD et al (2008) cT3N0 rectal cancer: potential overtreatment with preoperative chemoradiotherapy is warranted. 26:368–373
Guillem JG, Moore HG, Paty PB et al (2003) Adequacy of distal resection margin following preoperative combined modality therapy for rectal cancer. Ann Surg Oncol 10:824
Gunderson LL, Sargent DJ, Tepper JE et al (2004) Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis. J Clin Oncol 22:1785–1796
Habr-Gama A, de Souza PM, Ribeiro U et al (1998) Low rectal cancer: impact of radiation and chemotherapy on surgical treatment. Dis Colon Rectum 41:1087–1096
Habr-Gama A, Perez RO, Nadalin W et al (2004) Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy. Ann Surg 240:711–718
Hadfield MB, Nicholson AA, MacDonald AW et al (1997) Preoperative staging of rectal carcinoma by magnetic resonance imaging with a pelvic phased-array coil. Br J Surg 84:529–531
Hall NR, Finan PJ, al-Jaberi T et al (1998) Circumferential margin involvement after mesorectal excision of rectal cancer with curative intent. Predictor of survival but not local recurrence? Dis Colon Rectum 41:979–983
Hama Y, Makita K, Yamana T et al (2006) Mucinous adenocarcinoma arising from fistula in ano: MRI findings. AJR Am J Roentgenol 187:517–521
Hanski C (1995) Is mucinous carcinoma of the colorectum a distinct genetic entity? Br J Cancer 72:1350–1356
Harrison JC, Dean PJ, el-Zeky F et al (1994) From Dukes through Jass: pathological prognostic indicators in rectal cancer. Hum Pathol 25:498–505
Heald RJ, Ryall RD (1986) Recurrence and survival after total mesorectal excision for rectal cancer. Lancet 1:1479–1482
Heidenreich A, Collarini HA, Paladino AM et al (1966) Cancer in anal fistulas: report of two cases. Dis Colon Rectum 9:371–376
Hemminki K, Li X (2001) Incidence trends and risk factors of carcinoid tumors. A nationwide epidemiologic study from Sweden. Cancer 92:2204–2210
Hermanek P, Gospodarowicz MK, Hutter RVP, Sobin LH (eds) (1995) Prognostic factors in cancer. Springer, Berlin
Hida J, Yasutomi M, Fujimoto K et al (1997a) Does lateral lymph node dissection improve survival in rectal cancer? Examination of node metastases by the clearing method. J Am Coll Surg 184:475–480
Hida J, Yasutomi M, Maruyama T et al (1997b) Lymph node metastases detected in the mesorectum distal to carcinoma of the rectum by the clearing method: justification of total mesorectal excision. J Am Coll Surg 184:584–588
Hiotis SP, Weber SM, Cohen AM et al (2002) Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: an analysis of 448 patients. J Am Coll Surg 194:131–135
Hjermstad BM, Helwig EB (1988) Tailgut cysts. Report of 53 cases. Am J Clin Pathol 89:139–147
Hobson KG, Ghaemmaghami V, Roe JP et al (2005) Tumors of the retrorectal space. Dis Colon Rectum 48:1964–1974
Hocht S, Mann B, Germer CT et al (2004) Pelvic sidewall involvement in recurrent rectal cancer. Int J Colorectal Dis 19:108–113
Hocht S, Wiegel T, Hammad R et al (2002) Pelvic sites of recurrence in rectal cancer. Lancet 360:879–880
Hojo K, Koyama Y, Moriya A et al (1982) Lymphatic spread and its prognostic value in patients with rectal cancer. Am J Surg 144:350–354
Horn A, Dahl O, Morild I (1991) Venous and neural invasion as predictors of recuurence in rectal adenocarcinoma. Dis Colon Rectum 34:798–804
Huguier M, Houry S, Barrier A (2001) Local recurrence of cancer of the rectum. Am J Surg 182:437–439
Hung SSJ (1989) Small cell carcinoma of the colon – a case report and literature review. J Clin Gastroenterol 11:335–339
Hussain SM, Outwater EK, Siegelman ES (1999) Mucinous versus non-mucinous rectal carcinomas: differentiation with MR imaging. Radiology 213:79–85
Janjan NA, Khoo VS, Abbruzzese J et al (1999) Tumor downstaging and sphincter preservation with preoperative chemoradiation in locally advanced rectal cancer: the M. D. Anderson Cancer Center experience. Int J Radiat Oncol Biol Phys 44:1027–1038
Jao SW, Beart RW Jr, Spencer RJ et al (1985) Retrorectal tumors. Mayo Clinic experience, 1960–1979. Dis Colon Rectum 28:644–652
Jass JR, Sobin LH (1993) World Health Organization, International Histological Classification of Tumours, 2nd edn. Springer, Berlin
Jeffery GM, Hickey BE, Hider P (2002) Follow-up strategies for patients treated for non-metastatic colorectal cancer. (Cochrane Database System Review) Oxford United Kingdom, Cochrane Library, CD002200
Jemal A, Siegel R, Ward E et al (2008) Cancer statistics, 2008. CA Cancer J Clin 58:71–96
Jessup JM, Menk HR, Fremgen A et al (1997) Diagnosing colorectal carcinoma: clinical and molecular approaches. CA Cancer J Clin 47:70–92
Johnson KM, Leavitt GD, Kayser HW (1997) Total-body MR imaging in as little as 18 seconds. Radiology 202:252–256
Kang H, O’Connell JB, Maggard MA et al. (2005) A 10-year outcomes evaluation of mucinous and signet-ring cell carcinoma of the colon and rectum. Dis Colon Rectum 48:1161-1168
Kazama Y, Watanabe T, Kanazawa T et al (2005) Mucinous carcinoma of the colon and rectum show higher rates of microsatellite instability and lower rates of chromosomal instability. Cancer 103:2023–2029
Kievit J (2002) Follow-up of patients with colorectal cancer: numbers needed to test and treat. Eur J Cancer 38:986–999
Kim H, Jen J, Vogelstein B et al (1994) Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA errors in microsatellite sequences. Am J Pathol 145:148–156
Kim JH, Beets GL, Kim MJ et al (2004a) High-resolution MR imaging for nodal staging in rectal cancer: are there any criteria in addition to the size? Eur J Radiol 52:78–83
Kim MJ, Huh YM, Park YN et al (1999) Colorectal mucinous carcinoma: findings on MRI. J Comput Assist Tomogr 23:291–296
Kim MJ, Kim WH, Kim NK et al (1997) Tailgut cyst: multilocular cystic appearance on MRI. J Comput Assist Tomogr 21:731–732
Kim MJ, Lim JS, Oh YT et al (2004b) Preoperative MRI of rectal cancer with and without rectal water filling: an intraindividual comparison. AJR Am J Roentgenol 182:1469–1476
Kim MJ, Park JS, Park SI et al (2003) Accuray in differentiation of mucinous and nonmucinous rectal carcinoma on MR imaging. J Comput Assist Tomogr 27:48–55
Kim NK, Kim MJ, Park JK et al (2000) Preoperative staging of rectal cancer with MRI: accuracy and clinical usefulness. Ann Surg Oncol 7:732–737
Kim SH, Lee JM, Lee MW et al (2008) Sonography transmission gel as endorectal contrast agent for tumor visualization in rectal cancer. AJR Am J Roentgenol 191:186–189
Kinkel K, Lu Y, Both M et al (2002) Detection of hepatic metastases from cancers of the gastrointestinal tract by using noninvasive imaging methods (US, CT, MR imaging, PET): a meta-analysis. Radiology 224:748–756
Kjeldsen BJ, Kronborg O, Fenger C et al (1997) A prospective randomized study of follow-up after radical surgery of colorectal cancer. Br J Surg 84:666–669
Klöppel G, Rindi G, Anlauf M et al (2007) Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Arch 451:29–38
Knudsen JB, Nilsson T, Sprechler M et al (1983) Venous and nerve invasion as prognostic factors in postoperative survival of patients with resectable cancer of the rectum. Dis Colon Rectum 26:613–617
Koh DM, Brown G, Husband JE (2006) Nodal staging in rectal cancer. Abdom Imaging 31:652–659
Koh DM, Brown G, Temple L et al (2004) Rectal cancer: mesorectal lymph nodes at MR imaging with USPIO versus histopathologic findings – initial observations. Radiology 231:91–99
Koh DM, Brown G, Temple L et al (2005) Distribution of mesorectal lymph nodes in rectal cancer: in vivo MR imaging compared with histopathological examiantion. Initial observations. Eur Radiol 15:1650–1657
Koh DM, Collins DJ (2007) Diffusion-weighted MRI in the body: applications and challenges in oncology. AJR Am J Roentgenol 188:1622–1635
Koh DM, Takahara T, Imai Y et al (2007) Practical aspects of assessing tumors using clinical diffusion-weighted imaging in the body. Magn Reson Med Sci 6:211–224
Kraemer M, Wiratkapun S, Seow-Choen F et al (2001) Stratifying risk factors for follow-up: a comparison of recurrent and nonrecurrent colorectal cancer. Dis Colon Rectum 44:815–821
Krasna MJ, Flancbaum L, Cody RP et al (1988) Vascular and neural invasion in colorectal carcinoma. Incidence and prognostic significance. Cancer 61:1018–1023
Krook JE, Moertel CG, Gunderson LL et al (1991) Effective surgical adjuvant therapy for high-risk rectal carcinoma. N Engl J Med 324:709–715
Kruger DG, Riederer SJ, Grimm RC et al (2002) Continuously moving table data acquisition method for long FOV contrast enhanced MRA and whole body MRI. Magn Reson Med 47:224–231
Kuo LJ, Chern MC, Tsou MH et al (2005) Interpretation of magnetic resonance imaging for locally advanced rectal carcinoma after preoperative chemoradiation therapy. Dis Colon Rectum 48:23–28
Kwee TC, Takahara T, Ochiai R et al (2008) Diffusion-weighted whole-body imaging with background body signal suppression (DWIBS): features and potential applications in oncology. Eur Radiol 18:1937–1952
Ky A, Sohn N, Weinstein MA et al (1998) Carcinoma arising in anorectal fistulas of Crohn’s disease. Dis Colon Rectum 41:992–996
Lahaye MJ, Engelen SM, Kessels AG et al (2008) USPIO-enhanced MR imaging for nodal staging in patients with primary rectal cancer: predictive criteria. Radiology 246:804–811
Lahaye MJ, Engelen SM, Nelemans PJ et al (2005) Imaging for predicting the risk factors – the circumferential resection margin and nodal disease – of local recurrence in rectal cancer: a meta-analysis. Semin Ultrasound CT MR 26:259–268
Laufman H, Saphir O (1951) Primary linits plastica type of carcinoma of the colon. Arch Surg 62:79–91
Lee SH, McGregor DH, Kuziez MN (1981a) Malignant transformation of perianal condyloma acuminatum. A case report with review of the literature. Dis Colon Rectum 24:462–467
Lee SH, Zucker M, Sato T (1981b) Primary adenocarcinoma of the anal gland with secondary perianal fistula. Hum Pathol 12:1034–1037
Lehnert T, Methner M, Pollok A et al (2002) Multivisceral resection for locally advanced primary colon and rectal cancer: an analysis of prognostic factors in 201 patients. Ann Surg 235:217–225
Leiner T, Nijenhuis RJ, Maki JH (2004) Use of a three-station phased array coil to improve peripheral contrast-enhanced magnetic resonance angiography. J Magn Reson Imaging 20:417–425
Lengauer C, Kinzler KW, Vogelstein B (1997) Genetic instability in colorectal cancers. Nature 386:623–627
Levert LM, Van Rooyen W, Van Den Bergen HA (1996) Cysts of the tailgut. Eur J Surg 162:149–152
Lewis JJ, Leung D, Woodruff JM et al (1998) Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg 228:355–365
Lim KE, Hsu WC, Wang CR (1998) Tailgut cyst with malignancy: MR imaging findings. AJR Am J Roentgenol 170:1488–1490
Llyod RV (2003) Practical markers used in the diagnosis of neuroendocrine tumors. Endocr Pathol 14:293–301
Lockhart-Mummery HE (1975) Symposium. Crohn’s disease: anal lesions. Dis Colon Rectum 18:200–202
Longo WE, Johnson FE (2002) The preoperative assessment and postoperative surveillance of patients with colon and rectal cancer. Surg Clin North Am 82:1091–1108
Ludwig U, Sommer G, Zaitsev M et al (2006) 2D axial moving table acquisitions with dynamic slice adaption. Magn Reson Med 55:423–430
Luna-Perez P, Bustos-Cholico E, Alvarado I et al (2005) Prognostic significance of circumferential margin involvement in rectal adenocarcinoma treated with preoperative chemradiotherapy and low anterior resection. J Surg Oncol 90:20–25
Luna-Perez P, Rodriguez-Ramirez S, Rodriguez-Coria DF et al (2001) Preoperative chemoradiation therapy and anal sphincter preservation with locally advanced rectal adenocarcinoma. World J Surg 25:1006–1011
Maier AG, Kersting-Sommerhoff B, Reeders JW et al (2000) Staging of rectal cancer by double-contrast MR imaging using the rectally administered superparamagnetic iron oxide contrast agent ferristine and i.v. gadodiamide injection: results of a multicenter phase II trial. J Magn Reson Imaging 12:651–660
Makela JT, Laitinen SO, Kairaluoma MI (1995) Five-year follow-up after radical surgery for colorectal cancer: results of a prospective randomized trial. Arch Surg 130:1062–1067
Markus J, Morrissey B, deGara C et al (1997) MRI of recurrent rectosigmoid carcinoma. Abdom Imaging 22:338–342
Marr R, Birbeck K, Garvican J et al (2005) The modern abdominoperineal excision. The next challenge after total mesorectal excision. Ann Surg 242:74–82
Martling AL, Holm T, Rutqvist LE et al (2000) Effect of a surgical training programme on outcome of rectal cancer in the county of Stockholm: Stockholm colorectal cancer study group, basingstoke bowel cancer research project. Lancet 356:93–96
Masaki T, Sugiyama M, Atomi Y et al (2001) The indication of local excision for T2 rectal carcinomas. Am J Surg 181:133–137
Mathur P, Smith JJ, Ramsey C et al (2003) Comparison of CT and MRI in the pre-operative staging of rectal adenocarcinoma and prediction of circumferential margin involvement by MRI. Colorectal Dis 5:396–401
Matsuoka H, Nakamura A, Sugiyama M et al (2004) MRI diagnosis of mesorectal lymph node metastasis in patients with rectal carcinoma. What is the optimal criterion? Anticancer Res 24:4097–4102
Mazur MT, Clark HB (1983) Gastric stromal tumors: reappraisal of histogenesis. Am J Surg Pathol 7:507–519
Medich D, McGinty J, Parda D et al (2001) Preoperative chemoradiotherapy and radical surgery for locally advanced distal rectal adenocarcinoma: pathologic findings and clinical implications. Dis Colon Rectum 44:1123–1128
Merchant NB, Guillem JG, Paty PB et al (1999) T3N0 rectal cancer: results following sharp mesorectal excision and no adjuvant therapy. J Gastrointest Surg 3:642–647
MERCURY Study Group (2007) Extramural depth of tumor invasion at thin-section MR in patients with rectal cancer: results of the MERCURY Study. Radiology 243: 132–139
Merkel S, Mansmann U, Siassi M et al (2001) The prognostic inhomogeneity in pT3 rectal carcinomas. Int J Colorectal Dis 16:298–304
Miller AR (1998) Multidisciplinary management of recurrent colorectal cancer. Surg Oncol 7:209–221
Minsky BD, Cohen AM, Kemeny N et al (1992) Combined modality therapy of rectal cancer: decreased acute toxicity with the preoperative approach. J Clin Oncol 10:1218–1224
Minsky BD, Mies C, Rich TA et al (1987) Colloid carcinoma of the colon and rectum. Cancer 60:3103–3112
Monig SP, Baldus SE, Zirbes TK et al (1999) Lymph node size and metastatic infiltration in colon cancer. Ann Surg Oncol 6:579–581
Moran MR, James EC, Rothenberger DA et al (1992) Prognostic value of positive lymph nodes in rectal cancer. Dis Colon Rectum 35:579–581
Moreira LF, Hizuta A, Iwagaki H et al (1994) Lateral lymph node dissection for rectal carcinoma below the peritoneal reflection. Br J Surg 81:293–296
Morikawa E, Yasutomi M, Shindou K et al (1994) Distribution of metastatic lymph nodes in colorectal cancer by the modified clearing method. Dis Colon Rectum 37:219–223
Moulopoulos LA, Karvouni E, Kehagias D et al (1999) MR imaging of complex tail-gut cysts. Clin Radiol 54:118–122
Nagtegaal ID, Gaspar C, Marijnen CA et al (2004) Morphological changes in tumor type after radiotherapy are accompanied by changes in gene expression profile but not clinical behaviour. J Pathol 204:183–192
Nagtegaal ID, Gosens M J, Marijnen CA et al (2007) Combinations of tumor and treatment parameters are more discriminative for prognosis than the present TNM system in rectal cancer. J Clin Oncol 25:1647–1650
Nagtegaal ID, Marijnen CA, Kranenbarg EK et al (2002a) Circumferential margin involvement is still an important predictor of local recurrence in rectal carcinoma: not one millimeter but two millimeters is the limit. Am J Surg Pathol 26:350–357
Nagtegaal ID, Quirke P (2008) What is the role for the circumferential margin in the modern treatment of rectal cancer? J Clin Oncol 28:303–312
Nagtegaal ID, van der Velde CJ et al (2002b) Macroscopic evaluation of rectal cancer resection specimen: clinical significance of the pathologist in quality control. J Clin Oncol 20:1729–1734
National Institutes of Health Consensus Conference. (1990) JAMA 246:1444–1450
Negri FV, Wotherspoon A, Cunningham D et al (2005) Mucinous histology predicts for reduced fluorouracil responsiveness and survival in advanced colorectal cancer. Ann Oncol 16:1305–1310
Nissan A, Guillem JG, Paty PB et al (1999) Signet-ring cell carcinoma of the colon and rectum: a matched control study. Dis Colon Rectum 42:1176–1180
Nozoe T, Anai H, Nasu S et al (2000) Clinicopathological characteristics of mucinous carcinoma of the colon and rectum. J Surg Oncol 75:103–107
Odone V, Chang L, Caces J et al (1982) The natural history of colorectal carcinoma in adolescents. Cancer 49:1716–1720
Ohlsson B, Breland U, Ekberg H et al (1995) Follow-up after curative surgery for colorectal carcinoma: randomized comparison with no follow-up. Dis Colon Rectum 38:619–626
Okizuka H, Sugimura K, Yoshizako T et al (1996) Rectal carcinoma: prospective comparison of conventional and gadopentate dimeglumine enhanced fat-suppressed MR imaging. J Magn Reson Imaging 6:465–471
Okuyama T, Korenaga D, Tamura S et al (1999) The effectiveness of chemotherapy with cisplatin and 5-fluorouracil for recurrent small cell neuroendocrine carcinoma of the rectum: report of a case. Jpn J Surg 29:165–169
Panaccione JL, Ross PR, Torres GM et al (1991) Rectal barium in pelvic MR imaging: initial results. J Magn Reson Imaging 1:605–607
Park YJ, Youk EG, Choi HS et al (1999) Experience of 1446 rectal cancer patients in Korea and analysis of prognostic factors. Int J Colorectal Dis 14:101–106
Patrinou V, Petrochilos J, Batistatou A et al (2001) Mucinous adenocarcinoma arising in chronic perianal fistula. J Clin Gastroenterol 33:175–176
Pema PJ, Bennett WF, Bova JG et al (1994) CT vs MRI in diagnosis of recurrent rectosigmoid carcinoma. J Comp Assist Tomogr 18:256–261
Peschaud F, Cuenod CA, Benoist S et al (2005) Accuracy of magnetic resonance imaging in rectal cancer depends on location of the tumor. Dis Colon Rectum 8:1603–1609
Picon AI, Moore HG, Sternberg SS et al (2003) Prognostic significance of depth of gross or microscopic perirectal fat invasion in T3N0M0 rectal cancers following sharp mesorectal excision and no adjuvant therapy. Int J Colorectal Dis 18:487–492
Pidhorecky I, Cheney RT, Kraybill WG et al (2007) Gastrointestinal stroma tumors: current diagnosis, biologic behaviour, and management. Ann Surg Oncol 7:705–712
Pietra N, Sarli L, Costi R et al (1998) Role of follow-up in management of local recurrences of colorectal cancer: a prospective, randomized study. Dis Colon Rectum 41:1127–1133
Quirke P, Dixon MF (1988) The prediciton of local recurrence in rectal adenocarcinoma by histopathological examination. Int J Colorectal Dis 3:127–131
Quirke P, Durdey P, Dixon MF, et al (1986) Local recurrence of rectal adenocarcinoma due to inadequate surgical resection: histopathological study of lateral tumor spread and surgical excision. Lancet 2:996–999
Rao TR, Hambrick E, Abcarian H et al (1982) Colorectal linits plastica. Dis Colon Rectum 25:239–244
Reerink O, Verschueren R, Szabo B et al (2003) A favourable pathological stage after neo-adjuvant radiochemotherapy in patients with initially irresectable rectal cancer correlates with a favourable prognosis. Eur J Cancer 39:1127–1132
Renehan AG, Egger M, Saunders MP et al (2002) Impact on survival of intensive follow-up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials. BMJ 324:1–8
Rioux M, Mailloux C (1997) Crescent-shaped necrosis: a new imaging sign suggestive of stromal tumor of the small bowel. Abdom Imaging 22:376–380
Ryan DP, Compton CC, Mayer RJ (2000) Carcinoma of the anal canal. N Engl J Med 342:792–800
Saclarides TJ, Bhattacharyya AK, Britton-Kuzel C et al (1994a) Predicting lymph node metastases in rectal cancer. Dis Colon Rectum 37:52–57
Saclarides TJ, Szeluga D, Staren ED (1994b) Neuroendocrine carcinoma of the colon and rectum – results of a ten-year experience. Dis Colon Rectum 37:635–642
Sabati M, Lauzon ML, Mahallati H et al (2006) Interactive continuously moving table (iCMT) large field-of-view real-time MRI. Magn Reson Med 55:1202–1209
Sagar PM, Pemberton JH (1996) Surgical management of locally recurrent rectal cancer. Br J Surg 83:293–304
Salmon RJ, Zafrani B, Labib A et al (1986) Prognosis of cloacogenic ans squamous cancers of the anal canal. Dis Colon Rectum 29:336–340
Sandrasegaran K, Rajesh A, Rushing DA et al (2005) Gastrointestinal stromal tumors: CT and MRI findings. Eur Radiol 15:1407–1414
Sasaki O, Atkin WS, Jass JR (1987) Mucinous carcinoma of the rectum. Histopathology 11:259–272
Sauer R, Becker H, Hohenberger W et al (2004) Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 351:1731–1740
Schäfer AO, Baumann T, Pache G (2007) Preoperative staging of rectal cancer. Radiologe 47:635–651
Schäfer O, Langer M (2007) Detection of recurrent rectal cancer with CT, MRI and PET/CT. Eur Radiol 17:2044–2054
Schaefer JF, Schlemmer HP (2006) Total-body MR-imaging in oncology. Eur Radiol 16:2000–2015
Schmidt GP, Baur-Melnyk A, Herzog P et al (2005) High-resolution whole-body magnetic resonance image tumor staging with the use of parallel imaging versus dual-modality positron emission tomography-computed tomography: experience on a 32-channel system. Invest Radiol 40:743–753
Schoemaker D, Black R, Giles L et al (1998) Yearly colonoscopy, liver CT, and chest radiography do not influence 5-year survival of colorectal cancer patients. Gastroenterology 114:7–14
Secco GB, Fardelli R, Campora E et al (1994) Primary mucinous adenocarcinomas and signet-ring cell carcinomas of colon and rectum. Oncology 51:30–34
Secco GB, Fardelli R, Gianquinto D et al (2002) Efficacy and cost of risk-adapted follow-up in patients after colorectal cancer surgery: a prospective, randomized and controlled trial. J Surg Oncol 28:418–423
Shankaranarayanan A, Herfkens R, Hargreaves BM et al (2003) Helical MR: continuously moving table axial imaging with radial acquisitions. Magn Reson Med 50:1053–1060
Shepherd NA, Baxter KJ, Love SB (1995) Influence of local peritoneal involvement on pelvic recurrence and prognosis in rectal cancer. J Clin Pathol 48:849–855
Shirouzu K, Isomoto H, Kakegawa T (1993) Prognostic evaluation of perineural invasion in rectal cancer. Am J Surg 165:233–237
Sim HL, Tan KY, Poon PL et al (2008) Primary signet ring cell carcinoma with peritoneal dissemination and gastric secondaries. World J Gastroenterol 14:2118–2120
Simunovic M, Sexton R, Rempel E et al (2003) Optimal preoperative assessment and surgery for rectal cancer may greatly limit the need for radiotherapy. Br J Surg 90:999–1003
Smith NJ, Shihab O, Arnaout A et al (2008a) MRI for detection of extramural vascular invasion in rectal cancer. AJR Am J Roentgenol 191:1517–1522
Smith R, Hicks D, Tomljanovich PI et al (2008b) Adenocarcinoma arising from chronic perianal Crohn’s disease: case report and review of the literature. Am Surg 74:59–61
Sommer G, Fautz HP, Ludwig U et al (2006) Multicontrast sequences with continuous table motion: a novel acquisition technique for extended field of view imaging. Magn Reson Med 55:918–922
Sommer G, Schaefer AO, Baumann T et al (2008) Sliding Multislice MRI for abdominal staging of patients with pelvic malignancies: a pilot study. J Magn Reson Imaging 27:666–672
Steup WH, Moriya Y, van de Velde CJ (2002) Patterns of lymphatic spread in rectal cancer. A topographical analysis on lymph node metastases. Eur J Cancer 38:911–918
Stoker J, Rociu E et al (2000) Imaging of anorectal disease. Br J Surg 87:10–27
Stewart BW, Kleihues P (eds) (2003) World Health Organization World Cancer Report. International Agency for Researh on Cancer, pp 12–21
Stewart RJ, Humphreys WG et al (1986) The presentation and management of presacral tumors. Br J Surg 73:153–155
Sugarbaker PH (2001) Mucinous colorectal carcinoma. J Surg Oncol 77:282–283
Suzuki K, Muoto T, Sawada T (1995) Prevention of local recurrence by extended lymphadenectomy for rectal cancer. Surg Today 25:795–801
Symonds DA, Vickery AL (1976) Mucinous carcinoma of the colon and rectum. Cancer 37:1891–1900
Takahashi T, Ueno M, Azekura K et al (2000) Lateral node dissection and total mesorectal excision for rectal cancer. Dis Colon Rectum 43:59–68
Takahashi Y, Tucker SL, Kitadai Y et al (1997) Vessel counts and expression of vascular endothelial growth factor as prognostic factors in node-negative colon cancer. Arch Surg 132:541–546
Talbot IC, Ritchie S, Leighton MH et al (1980) The clinical significance of invasion of veins by rectal cancer. Br J Surg 67:439–442
Tampi C, Lotwala V, Lakdawala M et al (2007) Retrorectal cyst hamartoma (tailgut cyst) with malignant transformation. Gynecol Oncol 105:266–268
Tang R, Wang JY, Chen JS et al (1995) Survival impact of lymph node metastasis in TNM stage III carcinoma of the colon and rectum. J Am Coll Surg 180:705–712
Tarazi R, Nelson RL (1994) Anal adenocarcinoma: a comprehensive review. Semin Surg Oncol 10: 235–240
Theilmann RJ, Borders R, Trouard TP et al (2004) Changes in water mobility measured by diffusion MRI predict response of metastatic breast cancer to chemotherapy. Neoplasia 6:831–837
Titu LV, Nicholson AA, Hartley JE et al (2006) Routine follow-up by magnetic resonance imaging does not improve detection of resectable local recurrences from colorectal cancer. Ann Surg 243:348–352
Traube J, Simpson S, Riddell RH et al (1980) Crohn’s disease and adenocarcinoma of the bowel. Dig Dis Sci 25:939–944
Tung SY, Wu CS, Chen PC (1996) Primary signet ring cell carcinoma of colorectum: an age- and sex-matched controlled study. Am J Gastroenterol 91:2195–2199
Ueno H, Hase K, Mochizuki H (2001a) Criteria for extramural perineural invasion as a prognostic factor in rectal cancer. Br J Surg 88:994–1000
Ueno H, Mochizuki H, Hashiguchi Y et al (2001b) Prognostic determinants of patients with lateral nodal involvement by rectal cancer. Ann Surg 234:190–197
Uhlig BE, Johnson RL (1975) Presacral tumors and cysts in adults. Dis Colon Rectum 18:581–589
Umpleby HC, Ranson DL, Williamson RC (1985) Peculiarities of mucinous colorectal carcinoma. Br J Surg 72:715–718
Uronis HE, Bendell JC (2007) Anal cancer: an overview. Oncologist 12:524–534
van Lingen CP, Zeebregts CJ, Gerritsen JJ et al (2003) Local recurrence of rectal cancer after total mesorectal excision without preoperative radiotherapy. Int J Gastrointest Cancer 34:129–134
Vernon SE, Unger H, Traitz JJ (1981) Diffusely infiltrating carcinoma of the colon (linitis plastica type). Dis Colon Rectum 24:391–394
Vilor M, Tsutsumi Y, Osamura Y et al (1995) Small cell neuronedocrine carcinoma of the rectum. Pathol Int 45:605–609
Vliegen RF, Beets GL, Lammering G et al (2008) Mesorectal fascia invasion after neoadjuvant chemotherapy and radiation therapy for locally advanced rectal cancer: accuracy of MR imaging for prediction. Radiology 246:454–462
Vliegen RF, Beets GL, von Meyenfeldt MF et al (2005) Rectal cancer: MR imaging in local staging – is gadolinium-based contrast material helpful? Radiology 234:179–188
Vogl TJ, Pegios W, Mack MG et al (1997) Accuracy of staging rectal tumors with contrast-enhanced transrectal MR imaging. AJR Am J Roentgenol 168:1427–1434
Wallengren NO, Holtas S, Andren-Sandberg A et al (2000) Rectal carcinoma: double-contrast MR imaging for preoperative staging. Radiology 215:108–114
Weissleder R, Elizondo G, Wittenberg J et al (1990) Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology 175:489–493
Wibe A, Rendedal PR, Svensson E et al (2002a) Prognostic significance of the circumferential resection margin following total mesorectal excision for rectal cancer. Br J Surg 89:327–334
Wibe A, Syse A, Anderson E et al (2002b) Oncological outcomes after total mesorectal excision for cure of cancer of the lower rectum: anterior vs abdominoperineal resection. Dis Colon Rectum 47:48–58
Wied U, Nilsson T, Knudsen JB et al (1985) Postoperative survival of patients with potentially curable cancer of the colon. Dis Colon Rectum 28:333–335
Will O, Purkayastha S, Chan C et al (2006) Diagnostic precision of nanoparticle-enhanced MRI for lymph-node metastases: a meta-analysis. Lancet Oncol 7:52–60
Willett CG, Badizadegan K, Ancukiewicz M et al (1999) Prognostic factors in stage T3N0 rectal cancer: do all patients require postoperative pelvic irradiation and chemotherapy? Dis Colon Rectum 42:167–173
Wittekind C, Henson DE, Hutter RV et al (2001) TNM Supplement. A commentary for uniform use, 2nd edn. Wiley, New York, pp 117–119
Wolmark N, Fisher B, Wieand HS (1986) The prognostic value of the Dukes’ C class of colorectal cancer: an analysis of the NSABP clinical trials. Ann Surg 203:115–122
Wong NA, Shirazi T, Hamer-Hodges DW et al (2002) Adenocarcinoma arising within a Crohn’s-related anorectal fistula: a forum of anal gland carcinoma? Histopathology 40:302–304
Yang DM, Park CH, Jin W et al (2005) Tailgut cyst: MRI evaluation. AJR Am J Roentgenol 184:1519–1523
Yoo SY, Lee JH, Park KR et al (1994) Primary signet-ring-cell carcinoma of the rectum in a 12-year-old boy. Pediatr Surg Int 9:284–286
Younes M, Katikaneni PR, Lechago J (1993) The value of preoperative mucosal biopsy in the diagnosis of colorectal mucinous adenocarcinoma. Cancer 72:3588–3592
Zenni GC, Abraham K, Harford FJ et al (1998) Characteristics of rectal carcinomas that predict the presence of lymph node metastases: implications for patient selection for local therapy. J Surg Oncol 67:99–103
Zerhouni EA, Rutter C, Hamilton SR et al (1996) CT and MR imaging in the staging of colorectal carcinoma: report of the Radiology Diagnostic Oncology Group II. Radiology 200:443–451
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Schäfer, AO. (2009). Magnetic Resonance Imaging of Rectal Cancer. In: MRI of Rectal Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72833-7_4
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