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Logopenic Primary Progressive Aphasia

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Abstract

Logopenic primary progressive aphasia is an atypical variant of Alzheimer’s disease characterized by decreased rate of spontaneous language production. PET/MR imaging demonstrates cortical atrophy and corresponding hypometabolism, typically most severe in the left lateral temporoparietal region.

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Suggested Reading

  • Henry ML, Gorno-Tempini ML. The logopenic variant of primary progressive aphasia. Curr Opin Neurol. 2010;23(6):633–7.

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  • Leyton CE, Villemagne VL, Savage S, Pike KE, Ballard KJ, Piguet O, et al. Subtypes of progressive aphasia: application of the international consensus criteria and validation using β-amyloid imaging. Brain. 2011;134:3030–43.

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  • Madhavan A, Whitwell JL, Weigand SD, Duffy JR, Strand EA, Machulda MM, et al. FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. PLoS One. 2013;8(4):e62471.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology and Imaging Sciences, Emory University Hospital, Emory University Hospital, BG20, 1364 Clifton Road NE, Atlanta, GA, 30322, USA

    Michael J. Hoch MD

  2. Department of Radiology, Stony Brook University Hospital, 101 Nicolls Rd, HSC Lvl 4, Rm 120, Stony Brook, NY, 11794, USA

    Lev Bangiyev DO

  3. Department of Radiology, New York University Langone Medical Center, 660 First Ave., 2nd Floor, New York, NY, 10016, USA

    Timothy M. Shepherd MD, PhD

Authors
  1. Michael J. Hoch MD
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  2. Lev Bangiyev DO
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  3. Timothy M. Shepherd MD, PhD
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Correspondence to Lev Bangiyev DO .

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© 2018 Springer International Publishing AG

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Hoch, M.J., Bangiyev, L., Shepherd, T.M. (2018). Logopenic Primary Progressive Aphasia. In: PET/MR Imaging . Springer, Cham. https://doi.org/10.1007/978-3-319-65106-4_122

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  • DOI: https://doi.org/10.1007/978-3-319-65106-4_122

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-65105-7

  • Online ISBN: 978-3-319-65106-4

  • eBook Packages: MedicineMedicine (R0)

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