Abstract
Fine needle aspiration (FNA) biopsy is a useful diagnostic tool in the management of salivary gland pathology. FNA cytology for salivary disease can influence management decisions and inform counseling on therapeutic options. Compared to other forms of biopsy, FNA is simple, cost-effective, and safe while providing rapid information (Majewski et al. J Med Genet 48:580–589, 2011; Service Science 311:1544–1546, 2006). However, the large number of benign and malignant salivary tumors and inflammatory diseases with potential overlapping morphologies makes salivary cytology particularly challenging. There is a relative paucity of specific immunohistochemical stains and readily available molecular markers to accurately subtype salivary gland neoplasms. These factors can confound even experienced cytopathologists. Thus, both the imperfect accuracy of cytologic analysis and the confidence level of the pathologist need to be considered in the context of the clinical and imaging findings prior to any surgical intervention. This chapter explores the technique, utility, and limitations associated with FNA of salivary glands.
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Ryan, W.R., Sean Alemi, A., van Zante, A. (2018). Salivary Fine Needle Aspiration Biopsy. In: Gillespie, M., Walvekar, R., Schaitkin, B., Eisele, D. (eds) Gland-Preserving Salivary Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-58335-8_3
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