Abstract
Infants and small children receiving chronic peritoneal dialysis (PD) are particularly prone to chronic hypotension, because of the risk for hyponatremic hypovolemia that is related to their primary renal disease, specific nutritional needs, and peritoneal membrane characteristics. In this setting, if an acute “second” hit leads to a further decline in blood pressure, perfusion pressure autoregulatory mechanism may fail, leading to severe cerebral ischemic complications. Anterior ischemic optic neuropathy represents an acute ischemic disorder of the optic nerve head and a dramatic cause of sudden blindness. It occurs in about 1% of children on chronic PD. In infants at risk, specific strategies tackling the pathophysiological cascade should be applied to prevent PD-induced hypotension and its complications.
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Vidal, E. (2017). Hypotension in Infants on Peritoneal Dialysis. In: Warady, B., Schaefer, F., Alexander, S. (eds) Pediatric Dialysis Case Studies. Springer, Cham. https://doi.org/10.1007/978-3-319-55147-0_5
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DOI: https://doi.org/10.1007/978-3-319-55147-0_5
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