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Pediatric Inflammatory Bowel Disease pp 199–209Cite as

Differential Diagnosis of Inflammatory Bowel Disease

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Abstract

Numerous diseases can present with symptoms similar to IBD. In case of acute-onset diarrhea, infectious or allergic diseases and acute appendicitis should be ruled out before considering the diagnosis of IBD. Chronic or recurrent intestinal symptoms are more suggestive of IBD. Infection, celiac disease, or food allergy should all be entertained in the differential diagnosis in this situation. Neoplasm and vasculitic disorders are more rarely involved. Disorders of the immune system should be sought after, especially in cases of early-onset (<6 years) symptoms, as numerous monogenic disorders are currently being discovered with specific therapeutic options available. Less classic presentations of IBD can be encountered, leading to consideration of other diagnoses such as tumors or tuberculosis in cases of an abdominal mass, peptic disease in cases of isolated esophagogastroduodenal involvement, immunodeficiency syndromes, or trauma in cases of isolated perianal/perineal disease.

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Authors and Affiliations

  1. Unit of Pediatric Gastroenterology and Nutrition, Children’s Hospital, Amelie Raba Leon, 33076, Bordeaux, France

    Thierry Lamireau MD, PhD & Raphael Enaud

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  1. Thierry Lamireau MD, PhD
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  2. Raphael Enaud
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Correspondence to Thierry Lamireau MD, PhD .

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Editors and Affiliations

  1. Division of GI, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

    Petar Mamula

  2. Division of GI, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

    Andrew B. Grossman

  3. Division of GI, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

    Robert N. Baldassano

  4. Division of GI, Hepatology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

    Judith R. Kelsen

  5. Division of Pediatric Gastroenterology & Nutrition, University of South Carolina School of Medicine - Greenville, Greenville, South Carolina, USA

    Jonathan E. Markowitz

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Lamireau, T., Enaud, R. (2017). Differential Diagnosis of Inflammatory Bowel Disease. In: Mamula, P., Grossman, A., Baldassano, R., Kelsen, J., Markowitz, J. (eds) Pediatric Inflammatory Bowel Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-49215-5_17

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  • DOI: https://doi.org/10.1007/978-3-319-49215-5_17

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