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The Role of Capsule Endoscopy in the Diagnosis and Management of Celiac Disease and Refractory Diarrhea

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Capsule Endoscopy

Abstract

Celiac disease represents an immune-mediated intestinal injury as a result of intolerance to gluten, a protein found in wheat, rye, and barley. It affects genetically susceptible individuals with a prevalence ranging from 0.7 to 2 % in various communities. Symptoms vary from persistent and daily to subclinical, vague, and variable. They can include abdominal pain, diarrhea, bloating, as well as signs and symptoms of malabsorption, such as fatigue, nutritional deficiencies, anemia, osteoporosis, and ataxia. Other associated autoimmune phenomena include dermatitis herpetiformis, alopecia, and infertility. The majority of patients have clinical response to dietary restrictions, and persistent symptoms are most commonly secondary to gluten contamination. Capsule endoscopy has a distinct role in the diagnostic work-up for gluten enteropathy as well as in known celiac patients who demonstrate alarm or refractory symptomatology. This chapter will highlight the many benefits in the diagnosis and management of celiac disease.

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Correspondence to Amir Eshag Soumekh MD .

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Soumekh, A.E., Otaki, F. (2017). The Role of Capsule Endoscopy in the Diagnosis and Management of Celiac Disease and Refractory Diarrhea. In: Hass, D. (eds) Capsule Endoscopy. Springer, Cham. https://doi.org/10.1007/978-3-319-49173-8_6

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  • DOI: https://doi.org/10.1007/978-3-319-49173-8_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-49171-4

  • Online ISBN: 978-3-319-49173-8

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