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Nonalcoholic Fatty Liver Disease

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Abstract

Nonalcoholic fatty liver disease (NAFLD) is the main hepatic complication of obesity, insulin resistance, and diabetes and soon to become the leading cause for end-stage liver disease in the United States [1]. NAFLD is characterized by an accumulation of fat (steatosis) within >5 % of hepatocytes in the absence of secondary causes of hepatic steatosis. NAFLD is a spectrum of disease that ranges from steatosis (hepatic fat without significant hepatocellular injury) to nonalcoholic steatohepatitis (NASH; hepatic fat with hepatocellular injury) to advanced fibrosis and cirrhosis.

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Correspondence to Maya Balakrishnan .

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Seth, A., Balakrishnan, M. (2017). Nonalcoholic Fatty Liver Disease. In: Sellin, J. (eds) Managing Gastrointestinal Complications of Diabetes. Adis, Cham. https://doi.org/10.1007/978-3-319-48662-8_5

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  • DOI: https://doi.org/10.1007/978-3-319-48662-8_5

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