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Implications of Antibiotic Resistance in Potential Agents of Bioterrorism

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Antimicrobial Drug Resistance

Abstract

Antimicrobial resistance is a major global health issue that restricts treatment options for many bacterial infections. Although biothreat agents such as Bacillus anthracis, Burkholderia mallei, B. pseudomallei, Francisella tularensis and Yersinia pestis are usually susceptible to the recommended antimicrobial agents, there are naturally-occurring resistance mechanisms reported in several of these species, and the potential for release of genetically-engineered strains cannot be ruled out.

“The findings and conclusions in this manuscript are those of the author(s) and do not necessarily represent the views of the Centers for Disease Control and Prevention.”

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Authors and Affiliations

  1. Principal Investigator, Biodefense Research and Development Laboratory, Centers for Disease Control and Prevention, Atlanta, GA, 30333, USA

    Linda M. Weigel Ph.D.

  2. Division of Foodborne, Waterborne, and Environmental Diseases, National Center for Emerging, Zoonotic and Infectious Diseases, Centers for Disease Control and Prevention (Retired), 1600 Clifton Rd., N.E., MS: C-09, Atlanta, GA, 30333, USA

    Stephen A. Morse M.S.P.H., Ph.D.

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  1. Linda M. Weigel Ph.D.
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Correspondence to Linda M. Weigel Ph.D. .

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Editors and Affiliations

  1. Treiber Therapeutics, Cambridge, Massachusetts, USA

    Douglas L. Mayers

  2. Wayne State University School of Medicine, Detroit Medical Center, Detroit, Michigan, USA

    Jack D. Sobel

  3. Canada Research Chair in Antimicrobial Resistance, Centre de recherche en Infectiologie, University of Laval, Quebec City, Canada

    Marc Ouellette

  4. Division of Infectious Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA

    Keith S. Kaye

  5. Infection Control and Prevention Unit of Infectious Diseases, Assaf Harofeh Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel

    Dror Marchaim

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Weigel, L.M., Morse, S.A. (2017). Implications of Antibiotic Resistance in Potential Agents of Bioterrorism. In: Mayers, D., Sobel, J., Ouellette, M., Kaye, K., Marchaim, D. (eds) Antimicrobial Drug Resistance. Springer, Cham. https://doi.org/10.1007/978-3-319-47266-9_42

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