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Role of Inhalational Anesthetic Agents in Reducing Perioperative Mortality

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Abstract

In a recent Consensus Conference, among the 12 maneuvers that led to improved outcome in the perioperative period, inhalational anesthetic agents were the only anesthetic agents identified as contributing to reduced postoperative surgical mortality [1, 2]. Inhalational anesthetic agents have been shown to provide short-term as well as long-term protection [3, 4]. The evidence supporting mortality reduction via inhalational anesthetic agents seems to be growing.

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Correspondence to Laura Ruggeri MD .

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Summary Table

Summary Table

Clinical summary

Drug

Indications

Cautions

Side effects

Dosage

Notes

Inhalational agents

Myocardial protection during general anesthesia for cardiac surgery

Myocardial protection is dose and duration of inhalational anesthetic agent dependent

Common side effects of inhalational agents such as hypotension, myocardial depression, arrhythmias and effects on other solid organs

Unclear at the moment

Myocardial protection, decrease in infarct size and reduction in mortality during cardiac surgery have been well documented

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Chakravarthy, M., Ruggeri, L. (2017). Role of Inhalational Anesthetic Agents in Reducing Perioperative Mortality. In: Landoni, G., Ruggeri, L., Zangrillo, A. (eds) Reducing Mortality in the Perioperative Period. Springer, Cham. https://doi.org/10.1007/978-3-319-46696-5_4

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  • DOI: https://doi.org/10.1007/978-3-319-46696-5_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46695-8

  • Online ISBN: 978-3-319-46696-5

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