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Bronchopulmonary Dysplasia pp 79–92Cite as

Mycoplasma in Bronchopulmonary Dysplasia

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Abstract

Ureaplasma parvum, Ureaplasma urealyticum, and Mycoplasma hominis are considered commensals in the adult genitourinary tract, but these species are the most common organisms detected in infected amniotic fluid and placentas associated with preterm birth. Fetal exposure to these organisms in utero and vertical transmission perinatally have been associated with adverse neonatal outcomes including pneumonia, bronchopulmonary dysplasia (BPD), severe intraventricular hemorrhage, and necrotizing enterocolitis. This chapter reviews the experimental evidence for a role of these organisms in the pathogenesis of infection-mediated BPD with a focus on insights derived from animal models.

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  1. Department of Pediatrics, University of Maryland School of Medicine, 110 S. Paca Street, 8th floor, Baltimore, MD, 21201, USA

    Rose M. Viscardi MD

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  1. Department of Neonatology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA

    Vineet Bhandari

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Viscardi, R.M. (2016). Mycoplasma in Bronchopulmonary Dysplasia. In: Bhandari, V. (eds) Bronchopulmonary Dysplasia. Respiratory Medicine. Humana Press, Cham. https://doi.org/10.1007/978-3-319-28486-6_4

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