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Abnormal Female Puberty pp 23–45Cite as

Precocious Puberty

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Abstract

Precocious puberty affects nearly 1/5000–1/10,000 children with a high female predominance. Signs of pubertal development in girls younger than 8 years of age should prompt an evaluation. Physical examination to distinguish true precocious puberty from premature adrenarche or other similar diagnoses is essential. Laboratory analysis of gonadotropins and estradiol followed by targeted radiographic imaging is used to make the distinction between central (gonadotropin-dependent) or peripheral (gonadotropin-independent) precocious puberty. This chapter will provide a case-based approach to the complex issues associated with precocious puberty.

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Abbreviations

BMI:

Body mass index

CPP:

Central precocious puberty

GDPP:

Gonadotropin-dependent precocious puberty

GIPP:

Gonadotropin-independent precocious puberty

GnRH:

Gonadotropin-releasing hormone

MAS:

McCune–Albright syndrome

PP:

Precocious puberty

PPP:

Peripheral precocious puberty

TBI:

Traumatic brain injury

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Author information

Authors and Affiliations

  1. Division of Pediatric Endocrinology, Cohen Children’s Medical Center of NY, 1991 Marcus Avenue, Suite M100, Lake Success, NY, 11042, USA

    Jason Klein M.D.

  2. Hofstra Northwell School of Medicine, Hempstead, NY, 11549, USA

    Jason Klein M.D. & Patricia M. Vuguin M.Sc., M.D.

Authors
  1. Jason Klein M.D.
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  2. Patricia M. Vuguin M.Sc., M.D.
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Correspondence to Jason Klein M.D. .

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Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Manhasset, New York, USA

    Heather L. Appelbaum

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Klein, J., Vuguin, P.M. (2016). Precocious Puberty. In: Appelbaum, H. (eds) Abnormal Female Puberty. Springer, Cham. https://doi.org/10.1007/978-3-319-27225-2_2

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  • DOI: https://doi.org/10.1007/978-3-319-27225-2_2

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