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Breast Disease pp 233–247Cite as

Breast-Conserving Therapy: Hypofractionated and Conventional Whole-Breast Irradiation and Accelerated Partial-Breast Irradiation

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Abstract

Breast irradiation after breast-conserving surgery (BCS) is an essential component of breast conservation therapy for maximizing local control and overall survival. The most widely used fractionation regimen is 1.8- to 2-Gy daily fractions for a total of 45–50 Gy to the whole breast over 5 weeks with or without a boost to the surgical bed. However, the optimal dose and fractionation schedule for radiation therapy after BCS has not yet been defined. There is renewed interest in hypofractionation for whole-breast irradiation (WBI), and this approach has important practical advantages and biological implications. The convenience of this method may facilitate patient acceptance and compliance with radiation therapy. Irradiating only the tumor-bearing quadrant of the breast instead of irradiating the whole breast after BCS has also increased in popularity in the last decade.

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Authors and Affiliations

  1. Radiation Oncology, Medicana International Hospital, E5 Karayolu, Beylikduzu, Istanbul, Turkey

    Fusun Tokatlı MD

  2. Department of Radiation Oncology, Florence Nightingale Hospital, Gayrettepe, Istanbul, 34335, Turkey

    Maktav Dincer MD

Authors
  1. Fusun Tokatlı MD
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  2. Maktav Dincer MD
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Correspondence to Maktav Dincer MD .

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Editors and Affiliations

  1. Inst of Oncology,Ist Tıp Fak, Istanbul University, Istanbul, Turkey

    Adnan Aydiner

  2. General Surgery, Istanbul Univ Istanbul Fac of Med, Istanbul, Turkey

    Abdullah İgci

  3. Breast Surgery,, Magee-Womens Hospital, Pittsburg, USA

    Atilla Soran

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Tokatlı, F., Dincer, M. (2016). Breast-Conserving Therapy: Hypofractionated and Conventional Whole-Breast Irradiation and Accelerated Partial-Breast Irradiation. In: Aydiner, A., İgci, A., Soran, A. (eds) Breast Disease. Springer, Cham. https://doi.org/10.1007/978-3-319-26012-9_12

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  • DOI: https://doi.org/10.1007/978-3-319-26012-9_12

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