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Handbook of Gynecology pp 1–8Cite as

Benign Vulvar and Vaginal Pathology

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Abstract

Benign vulvar and vaginal pathology is common, consisting of a wide variety of lesions which include inflammatory conditions, pigmented lesions, neoplastic and nonneoplastic masses, and cysts. Women of all ages are affected. The majority of these lesions are clinically insignificant unless symptomatic or when they mimic malignancy. Rare lesions with premalignant potential are also present.

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References

  • Baker G, et al. Vulvar adnexal lesions. A 32-year, single-institution review from Massachusetts General Hospital. Arch Pathol Lab Med. 2013;137(9):1237–46.

    Article  PubMed  Google Scholar 

  • Brenn T. Atypical genital nevus. Arch Pathol Lab Med. 2011;135(3):317–20.

    PubMed  Google Scholar 

  • Carlson J, et al. Vulvar lichen sclerosus and squamous cell carcinoma: a cohort, case control, and investigational study with historical perspective; implications for chronic inflammation and sclerosis in the development of neoplasia. Hum Pathol. 1998;29(9):932–48.

    Article  CAS  PubMed  Google Scholar 

  • Cengiz F, et al. Dermoscopic and clinical features of pigmented skin lesions of the genital area. An Bras Dermatol. 2015;90(2):178–83.

    Article  PubMed  PubMed Central  Google Scholar 

  • Chan M, Zimarowski MJ. Vulvar dermatoses: a histopathologic review and classification of 183 cases. J Cutan Pathol. 2015;42:510–8.

    Article  PubMed  Google Scholar 

  • Chiesa-Vottero A. Histopathologic study of thin vulvar squamous cell carcinomas and associated cutaneous lesions: a correlative study of 48 tumors in 44 patients with analysis of adjacent vulvar intraepithelial neoplasia types and lichen sclerosus. Am J Surg Pathol. 2006;30(3):310–8.

    Article  PubMed  Google Scholar 

  • Docimo Jr S, et al. Bartholin’s abscess arising within hidradenoma papilliferum of the vulva: a case report. Cases J. 2008;1(1):282.

    Article  PubMed  PubMed Central  Google Scholar 

  • Duhan N, et al. Hidradenoma papilliferum of the vulva: case report and review of literature. Arch Gynecol Obstet. 2011;284(4):1015–7.

    Article  PubMed  Google Scholar 

  • Fistarol S, Itin PH. Diagnosis and treatment of lichen sclerosus. An update. Am J Clin Dermatol. 2013;14(1):27–47.

    Article  PubMed  Google Scholar 

  • Jackson, RJ. Dermatol. Surg. Oncol. 1984;10:2.

    Google Scholar 

  • Kanj et al. Journal of American Academy of Dermatology. 1992;27(5):Part 1:77.

    Google Scholar 

  • Jih D, et al. A histopathologic evaluation of vulvar melanosis. Arch Dermatol. 1999;135(7):857–8.

    Article  CAS  PubMed  Google Scholar 

  • Kaufmann T, et al. Cystic papillary hidradenoma of the vulva: case report and review of the literature. Gynecol Oncol. 1987;26(2):240–5.

    Article  CAS  PubMed  Google Scholar 

  • Lee E, et al. Pseudoepitheliomatous hyperplasia in lichen sclerosus of the vulva. Int J Gynecol Pathol. 2003;22(1):57–62.

    Article  PubMed  Google Scholar 

  • Madueke-Laveaux O, et al. Giant fibroepithelial stromal polyp of the vulva: largest case reported. Ann Surg Innov Res. 2013;7:8.

    Article  PubMed  PubMed Central  Google Scholar 

  • McCluggage W, et al. Myogenin expression in vulvovaginal spindle cell lesions: analysis of a series of cases with an emphasis on diagnostic pitfalls. Histopathology. 2013;63(4):545–50.

    PubMed  Google Scholar 

  • Murphy R. Lichen sclerosus. Dermatol Clin. 2010;28(4):707–15.

    Article  CAS  PubMed  Google Scholar 

  • Murzaku E, et al. Vulvar nevi, melanosis, and melanoma: an epidemiologic, clinical, and histopathologic review. J Am Acad Dermatol. 2014;71(6):1241–9.

    Article  PubMed  Google Scholar 

  • Navada M, et al. Large fibroepithelial polyp of vulva. Case Rep Dermatol Med. 2011;2011:273181.

    PubMed  PubMed Central  Google Scholar 

  • Nielsen G, Young RH. Mesenchymal tumors and tumor-like lesions of the female genital tract: a selective review with emphasis on recently described entities. Int J Gynecol Pathol. 2001;20(2):105–27.

    Article  CAS  PubMed  Google Scholar 

  • Nucci M, et al. Cellular pseudosarcomatous fibroe pithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma. Am J Surg Pathol. 2000;24(2):231–40.

    Google Scholar 

  • Ostor A, et al. Fibroepithelial polyps with atypical stromal cells (pseudosarcoma botryoides) of vulva and vagina. A report of 13 cases. Int J Gynecol Pathol. 1988;7(4):351–60.

    Article  CAS  PubMed  Google Scholar 

  • Parks A, et al. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands: report of a case and review of the literature. Am J Dermatopathol. 2012;34(1):104–9.

    Article  PubMed  Google Scholar 

  • Ribe A. Melanocytic lesions of the genital area with attention given to atypical genital nevi. J Cutan Pathol. 2008;35 Suppl 2:24–7.

    Article  PubMed  Google Scholar 

  • Rudolph R. Vulvar melanosis. J Am Acad Dermatol. 1990;23(5 Pt 2):982–4.

    Article  CAS  PubMed  Google Scholar 

  • Scurry J, et al. Histology of lichen sclerosus varies according to site and proximity to carcinoma. Am J Dermatopathol. 2001;23(5):413–8.

    Article  CAS  PubMed  Google Scholar 

  • Scurry J, et al. Mammary-like gland adenoma of the vulva: review of 46 cases. Pathology. 2009;41(4):372–8.

    Article  PubMed  Google Scholar 

  • Shah S, et al. Adenocarcinoma in situ arising in vulvar papillary hidradenoma: report of 2 cases. Int J Gynecol Pathol. 2008;27(3):453–6.

    Article  PubMed  Google Scholar 

  • Vazmitel M, et al. Hidradenoma papilliferum with a ductal carcinoma in situ component: case report and review of the literature. Am J Dermatopathol. 2008;30(4):392–4.

    Article  PubMed  Google Scholar 

  • Venkatesan A. Pigmented lesions of the vulva. Dermatol Clin. 2010;28(4):795–805.

    Article  CAS  PubMed  Google Scholar 

  • Virgili A, et al. Prospective clinical and epidemiologic study of vulvar lichen sclerosus: analysis of prevalence and severity of clinical features, together with Historical and Demographic Associations. Dermatology. 2014;228(2):145–51.

    Article  PubMed  Google Scholar 

  • Weyers W. Hypertrophic lichen sclerosus with dyskeratosis and parakeratosis – a common presentation of vulvar lichen sclerosus not associated with a significant risk of malignancy. Am J Dermatopathol. 2013;35(7):713–21.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. University of Southern California, Los Angeles, CA, USA

    Daman Samrao

  2. Laboratory Medicine Consultants, Las Vegas, NV, USA

    Daman Samrao

Authors
  1. Daman Samrao
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Correspondence to Daman Samrao .

Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynecology and Family Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA

    Donna Shoupe

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© 2016 Springer International Publishing Switzerland

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Samrao, D. (2016). Benign Vulvar and Vaginal Pathology. In: Shoupe, D. (eds) Handbook of Gynecology. Springer, Cham. https://doi.org/10.1007/978-3-319-17002-2_60-1

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  • DOI: https://doi.org/10.1007/978-3-319-17002-2_60-1

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  • Publisher Name: Springer, Cham

  • Online ISBN: 978-3-319-17002-2

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