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Early Colorectal Cancer

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Multidisciplinary Treatment of Colorectal Cancer

Abstract

In order to ensure a common language and to compare studies worldwide, there is a need for a common terminology. The chapter explains the terminology and classification of colorectal neoplastic precursor lesions and details to be fulfilled by the pathologist, such as measurement of polyp size, grading of villousness with focus on serrated lesions (hyperplastic polyps, sessile serrated adenoma, mixed polyp, traditional serrated adenoma) and grading of intraepithelial neoplasia/dysplasia (low grade, high grade).

Colorectal carcinomas need further histological evaluation of depth of infiltration. The definition of invasion is driven by the WHO and defined as invasion into the submucosal layer. Risk assessment of pT1 (depth of infiltration, type, grading, vascular invasion, margins, budding/tumour cell dissociation, perineural invasion) is a necessity for planning further procedures vs. endoscopic follow-up, only. Invasion should be reported according to Kikuchi as sm1-sm3 preferably in microns and in stalked polyps additionally by Haggitt levels.

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Authors and Affiliations

  1. Institute of Pathology, Klinikum Bayreuth, Bayreuth, Germany

    William Sterlacci & Michael Vieth

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  1. William Sterlacci
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Correspondence to Michael Vieth .

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Editors and Affiliations

  1. Department of Surgery, Odense University Hospital, Svendborg, Denmark

    Gunnar Baatrup

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Sterlacci, W., Vieth, M. (2021). Early Colorectal Cancer. In: Baatrup, G. (eds) Multidisciplinary Treatment of Colorectal Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-58846-5_28

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