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Laryngopharyngeal and Gastroesophageal Reflux pp 251–269Cite as

The Treatment of Reflux Disease: Standard and Alternative Approach

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Abstract

Since the 1960s, laryngopharyngeal reflux (LPR) has been hypothesized as reflux of gastric contents through the upper and lower esophageal sphincter (LES) into the larynx and pharynx (Francis and Vaezi, Clin Gastroenterol Hepatol, 13:1560–1566, 2015). A lax LES or increased pressure through a normal LES has often been considered a factor in LPR, resulting in reflux of acidic or nonacidic nature. Concurrent gastroesophageal reflux disease (GERD) is usually not present. This was first noted by Koufman with 81% of pH-documented LPR patients showing normal esophagoscopy (Koufman, Laryngoscope, 101:1–78, 1991). General symptoms of LPR include hoarseness of the voice, sore throat, chronic cough, globus sensation, dysphagia, sinusitis, and symptoms of asthma. LPR diagnosis via laryngoscopy is subjective and controversial at best with concern for overdiagnosis. Based on its assumed etiology, LPR treatment is based largely on the same standard of care used for GERD with very little in the way of prevention or LPR-specific treatments.

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Authors and Affiliations

  1. Center for Voice and Swallowing, White Plains Hospital, White Plains, NY, USA

    Craig Berzofsky

  2. Otolaryngology - Head and Neck Surgery, Southern Illinois University, Springfield, IL, USA

    Henya Sandhaus

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    Craig H. Zalvan

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Berzofsky, C., Sandhaus, H. (2020). The Treatment of Reflux Disease: Standard and Alternative Approach. In: Zalvan, C.H. (eds) Laryngopharyngeal and Gastroesophageal Reflux. Springer, Cham. https://doi.org/10.1007/978-3-030-48890-1_29

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