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Practical Trends in Anesthesia and Intensive Care 2019 pp 41–62Cite as

Neuromuscular Blocking Agents: Review on Agents (NMBA and Antagonists) and Monitoring

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Abstract

Neuromuscular blocking agents (NMBAs), whose origins date back to centuries, are pivotal in modern general anesthesia practice. This review will encompass old and new molecules, including principles available in the very next future, their mechanisms of action, old and new antagonists. We will discuss the role of neuromuscular monitoring (NMM), fundamental and now a standard of care for appropriate general anesthesia management. We hope this review will provide a comprehensive, practical, and integrated view of muscle paralysis in anesthesia and acute-care settings to ease the use of NMBAs and to allow a reliable and safe recovery from paralysis.

To Egidio Maestrone, MD

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Conflicts of Interests

Andrea De Gasperi received fees and travel reimbursements for lectures from MSD.

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Authors and Affiliations

  1. 2° Servizio Anestesia e Rianimazione—ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

    Beatrice Penzo, Laura Petrò & Andrea DeGasperi

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  1. Beatrice Penzo
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  2. Laura Petrò
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  3. Andrea DeGasperi
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Correspondence to Andrea DeGasperi .

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Editors and Affiliations

  1. San Paolo Hospital, Intensive Therapy Department, University of Milan, Milan, Italy

    Davide Chiumello

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Penzo, B., Petrò, L., DeGasperi, A. (2020). Neuromuscular Blocking Agents: Review on Agents (NMBA and Antagonists) and Monitoring. In: Chiumello, D. (eds) Practical Trends in Anesthesia and Intensive Care 2019. Springer, Cham. https://doi.org/10.1007/978-3-030-43873-9_4

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  • DOI: https://doi.org/10.1007/978-3-030-43873-9_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-43872-2

  • Online ISBN: 978-3-030-43873-9

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