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Pediatric Sleep-Disordered Breathing: Criteria and Spectrum of Disease

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Sleep Disordered Breathing in Children

Part of the book series: Respiratory Medicine ((RM))

Abstract

The spectrum of sleep-disordered breathing (SDB) is a construct that is universally considered when discussing diagnosis, treatment, and outcome of SDB. This spectrum of clinical severity of the disease is presumed to range from habitual snoring to obesity hypoventilation syndrome, including upper airway resistance syndrome (UARS) and obstructive sleep apnea syndrome (OSAS) of varying grades of severity. Diagnosis along the spectrum is commonly based on clinical perception, history, and physical findings, which are subsequently validated by the golden standard; i.e., overnight polysomnography (NPSG). Newer technologies or alternative ways to assess SDB, and more specifically, to gauge the SDB spectrum are increasingly being developed. These diagnostic approaches extend from objective to more subjective instruments. Our data-driven approach uncovered a spectrum of SDB severity clusters in children that can essentially be summarized and allocated into six distinct phenotypes.

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Notes

  1. 1.

    For the reader to generate the cluster assignment in the (non)hierarchical model for results of any NPSG, the Spruyt–Gozal classifier applet can be found at http://peds.uchicago.edu/sleepcenter/

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Authors and Affiliations

  1. Section of Pediatric Sleep Medicine, Department of Pediatrics, Comer’s Children Hospital, The University of Chicago, 5841 South Maryland Avenue, C104c, Chicago, IL, 60637, USA

    Karen Spruyt PhD

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  1. Karen Spruyt PhD
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Correspondence to Karen Spruyt PhD .

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Editors and Affiliations

  1. Section of Sleep Medicine, Pritzker School of Medicine, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    Leila Kheirandish-Gozal

  2. Pritzker School of Medicine, Comer Children's Hospital, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    David Gozal

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Spruyt, K. (2012). Pediatric Sleep-Disordered Breathing: Criteria and Spectrum of Disease. In: Kheirandish-Gozal, L., Gozal, D. (eds) Sleep Disordered Breathing in Children. Respiratory Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-725-9_18

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  • DOI: https://doi.org/10.1007/978-1-60761-725-9_18

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