Abstract
Opsoclonus-myoclonus-ataxia syndrome (OMA) typically causes opsoclonus (conjugate, multidirectional chaotic eye movements), myoclonus, and ataxia, sometimes together with sleep disorders, cognitive deficit, and behavioral disturbance. Myoclonus is brief and spontaneous, usually with stimulus-sensitive jerks involving the limbs, palate, face, larynx, or respiratory muscles. The syndrome can develop subacutely or progress quickly.
Causes of OMA may be categorized by age of onset. In children, OMA occurs most frequently in females between 6 months and 3 years. OMA is sometimes paraneoplastic and should be suspected where it is not preceded by a definite infection. Neuroblastoma is found in more than 50% of cases.
This chapter contains a video segment which can be found at the URL: https://doi.org/10.1007/978-1-60327-426-5_91
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Pang KK, de Sousa C, Lang B. A prospective study of the presentation and management of dancing eye syndrome/opsoclonus-myoclonus syndrome in the United Kingdom. Eur J Paediatr Neurol. 2010;14:156–61.
Bataller L, Graus F, Saiz A, et al. Clinical outcome in adult onset idiopathic or paraneoplastic opsoclonus-myoclonus. Brain. 2001;124:437–43.
Kanjanasut N, Phanthumchinda K, Bhidayasiri R. HIV-related opsoclonus-myoclonus-ataxia syndrome: report on two cases. Clin Neurol Neurosurg. 2010;112:572–4.
Author information
Authors and Affiliations
Electronic Supplementary material
Clip 1: the patient exhibits severe, high-frequency generalized myoclonic jerks and opsoclonus. Clip 2: examination 3 months after onset shows almost complete recovery except for mild bilateral action tremor.
OMA syndrome.mp4 (MP4 39,634KB)
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media New York
About this chapter
Cite this chapter
Bhidayasiri, R., Tarsy, D. (2012). Opsoclonus-Myoclonus-Ataxia Syndrome. In: Movement Disorders: A Video Atlas. Current Clinical Neurology. Humana, Totowa, NJ. https://doi.org/10.1007/978-1-60327-426-5_91
Download citation
DOI: https://doi.org/10.1007/978-1-60327-426-5_91
Published:
Publisher Name: Humana, Totowa, NJ
Print ISBN: 978-1-60327-425-8
Online ISBN: 978-1-60327-426-5
eBook Packages: MedicineMedicine (R0)