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Overview: Disease Recurrence After Liver Transplantation

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Abstract

The expected 1-year and 5-year patient survival rates after liver transplantation (LT) are 85–95 % and 75–85 %, respectively. The common causes of long-term mortality after LT are recurrence of primary liver disease or cancer for which LT was performed, cardiovascular events, de novo malignancy, and renal failure. In this book, we focus on disease recurrence after LT and critically analyze our current understanding of the incidence and diagnosis of disease recurrence, natural history, treatment options, and quality of life. Although disease recurrence is common after LT, only few conditions appear to have a major impact on graft survival. De novo diseases specific to LT recipients may also appear after LT in both adults and children. Early recognition of recurrent disease and de novo conditions will improve the survival of LT recipients.

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Correspondence to Paul J. Thuluvath MD, AGAF, FACG, FAASLD, FRCP .

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Thuluvath, P.J. (2016). Overview: Disease Recurrence After Liver Transplantation. In: Thuluvath, P. (eds) Disease Recurrence After Liver Transplantation. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2947-4_1

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