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Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care pp 801–817Cite as

Neuroprotection Strategies During Cardiopulmonary Bypass

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Abstract

The conduct of operative procedures for repair of congenital cardiac defects has evolved over time. Initially, intracardiac operations were performed with the aid of profound hypothermia and circulatory arrest. Over time, bypass and surgical techniques improved, obviating the need for deep hypothermic circulatory arrest for all but the most complex surgical procedures. Since the beginning, congenital cardiac diseases and the surgical intervention for these defects have been associated with neurologic dysfunction. The perioperative period has often been associated with the complication of neurologic injury, although it has become quite clear that the perioperative period is only one small point in time in which neurologic injury can occur. However, several important variables and techniques used for the management of congenital cardiac defects may help prevent neurologic injury. This chapter overviews some of the strategies utilized for neuroprotection.

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Authors and Affiliations

  1. Pediatric Cardiothoracic Surgery, Wake Forest Baptist Health/Brenner Children’s Hospital, Medical Center Boulevard, Winston-Salem, NC, 27157, USA

    Yoshio Ootaki

  2. Pediatric Cardiac Surgery, Wake Forest University, Winston-Salem, NC, USA

    Ross M. Ungerleider

Authors
  1. Yoshio Ootaki
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  2. Ross M. Ungerleider
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Correspondence to Yoshio Ootaki .

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Editors and Affiliations

  1. Dept. of Pediatric Cardiology, Children's Hospital Colorado, Univ. of Colorado, Denver, Aurora, Colorado, USA

    Eduardo M. Da Cruz

  2. Dept. Pediatric Cardiology, Children's Hospital Colorado, Univ. of Colorado, Denver, Aurora, Colorado, USA

    Dunbar Ivy

  3. Pediatric Cardiac Surgery, Children's Hospital Colorado, Univ. of Colorado, Denver, Aurora, Colorado, USA

    James Jaggers

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Ootaki, Y., Ungerleider, R.M. (2014). Neuroprotection Strategies During Cardiopulmonary Bypass. In: Da Cruz, E., Ivy, D., Jaggers, J. (eds) Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care. Springer, London. https://doi.org/10.1007/978-1-4471-4619-3_76

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  • DOI: https://doi.org/10.1007/978-1-4471-4619-3_76

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  • Online ISBN: 978-1-4471-4619-3

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