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New Challenges for the Analytical Evaluation of Reclaimed Water and Reuse Applications

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Book cover Wastewater Reuse and Current Challenges

Part of the book series: The Handbook of Environmental Chemistry ((HEC,volume 44))

Abstract

Presence of unregulated and not assessed organic microcontaminants in wastewater effluents represents a significant challenge to wastewater reclamation, especially if intended for human consumption or irrigation practices. Problems associated to the repeated release of treated wastewater in the environment for reuse applications, such as infiltration into the underground including pollution of ground water or accumulation in soil and plants, are still scarcely investigated. Consequently, comprehensive and high-throughput analytical methods have to be developed and validated to provide a comprehensive evaluation of these microcontaminants in water, soils and crops. This chapter aims to give an overview of the analytical strategies currently used in this field, its requirements and limitations.

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References

  1. Kalavrouziotis IK, Kokkinos P, Oron G, Fatone F, Bolzonella D, Vatyliotou M, Fatta-Kassinos D, Koukoulakis PH, Varnavas SP (2013) Current status in wastewater treatment, reuse and research in some Mediterranean countries. Desalin Water Treat. doi:10.1080/19443994.2013.860632

    Google Scholar 

  2. Lambropoulou DA, Nollet LML (eds) (2014) Transformation products of emerging contaminants in the environment. Wiley, Chichester

    Google Scholar 

  3. Rodil R, Quintana JB, López-Mahía P, Muniategui-Lorenzo S, Prada-Rodríguez D (2009) Multi-residue analytical method for the determination of emerging pollutants in water by solid-phase extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A 1216(14):2958–2969

    Article  CAS  Google Scholar 

  4. Martinez Bueno MJ, Agüera A, Gómez MJ, Hernando MD, García-Reyes JF, Fernández-Alba AR (2007) Application of liquid chromatography/quadrupole-linear ion trap mass spectrometry and time-of-flight mass spectrometry to the determination of pharmaceuticals and related contaminants in wastewater. Anal Chem 79(24):9372–9384

    Article  CAS  Google Scholar 

  5. Gracia-Lor E, Sancho JV, Hernández F (2011) Multi-class determination of around 50 pharmaceuticals, including 26 antibiotics, in environmental and wastewater samples by ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A 1218(16):2264–2275

    Article  CAS  Google Scholar 

  6. Busetti F, Linge KL, Heitz A (2009) Analysis of pharmaceuticals in indirect potable reuse systems using solid-phase extraction and liquid chromatography–tandem mass spectrometry. J Chromatogr A 1216(31):5807–5818

    Article  CAS  Google Scholar 

  7. Kasprzyk-Hordern B, Dinsdale RM, Guwy AJ (2008) Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra-performance liquid chromatography–electrospray tandem mass spectrometry. Anal Bioanal Chem 391(4):1293–1308

    Article  CAS  Google Scholar 

  8. Batt AL, Kostich MS, Lazorchak JM (2008) Analysis of ecologically relevant pharmaceuticals in wastewater and surface water using selective solid-phase extraction and UPLC − MS/MS. Anal Chem 80:5021–5030

    Article  CAS  Google Scholar 

  9. Lavén M, Alsberg T, Yu Y, Adolfsson-Erici M, Sun H (2009) Serial mixed-mode cation- and anion-exchange solid-phase extraction for separation of basic, neutral and acidic pharmaceuticals in wastewater and analysis by high-performance liquid chromatography–quadrupole time-of-flight mass spectrometry. J Chromatogr A 1216:49–62

    Article  CAS  Google Scholar 

  10. González-Mariño I, Quintana JB, Rodríguez I, Rodil R, González-Peñas J, Cela R (2009) Comparison of molecularly imprinted, mixed-mode and hydrophilic balance sorbents performance in the solid-phase extraction of amphetamine drugs from wastewater samples for liquid chromatography-tandem mass spectrometry determination. J Chromatogr A 1216:8435–8441

    Article  CAS  Google Scholar 

  11. Demeestere K, Petrović M, Gros M, Dewulf J, Van Langenhove H, Barceló D (2010) Trace analysis of antidepressants in environmental waters by molecularly imprinted polymer-based solid-phase extraction followed by ultra-performance liquid chromatography coupled to triple quadrupole mass spectrometry. Anal Bioanal Chem 396(2):825–837

    Article  CAS  Google Scholar 

  12. Gilart N, Marcé RM, Borrull F, Fontanals N (2012) Determination of pharmaceuticals in wastewaters using solid-phase extraction-liquid chromatography-tandem mass spectrometry. J Sep Sci 35:875–882

    Article  CAS  Google Scholar 

  13. Gros M, Pizzolato TM, Petrović M, de Alda MJL, Barceló D (2008) Trace level determination of β-blockers in waste waters by highly selective molecularly imprinted polymers extraction followed by liquid chromatography-quadrupole-linear ion trap mass spectrometry. J Chromatogr A 1189:374–384

    Article  CAS  Google Scholar 

  14. Kovalova L, Siegrist H, Singer H, Wittmer A, McArdell CS (2012) Hospital wastewater treatment by membrane bioreactor: performance and efficiency for organic micropollutant elimination. Environ Sci Technol 46(3):1536–1545

    Article  CAS  Google Scholar 

  15. Huntscha S, Singer HP, McArdell CS, Frank CE, Hollender J (2012) Multiresidue analysis of 88 polar organic micropollutants in ground, surface and wastewater using online mixed-bed multilayer solid-phase extraction coupled to high performance liquid chromatography–tandem mass spectrometry. J Chromatogr A 1268:74–83

    Article  CAS  Google Scholar 

  16. Negreira N, López de Alda M, Barceló D (2013) On-line solid phase extraction–liquid chromatography–tandem mass spectrometry for the determination of 17 cytostatics and metabolites in waste, surface and ground water samples. J Chromatogr A 1280:64–74

    Article  CAS  Google Scholar 

  17. Backe WJ, Field JA (2012) Is SPE necessary for environmental analysis? A quantitative comparison of matrix effects from large-volume injection and solid-phase extraction based methods. Environ Sci Technol 46:6750–6758

    Article  CAS  Google Scholar 

  18. Chaia AC, Banta-Green C, Field JA (2008) Eliminating solid phase extraction with large-volume injection LC/MS/MS: analysis of illicit and legal drugs and human urine indicators in US wastewaters. Environ Sci Technol 42:8841–8848

    Article  CAS  Google Scholar 

  19. Backe WJ, Ort C, Brewer AJ, Field JA (2011) Analysis of androgenic steroids in environmental waters by large-volume injection liquid chromatography tandem mass spectrometry. Anal Chem 83(7):2622–2630

    Article  CAS  Google Scholar 

  20. Martínez Bueno MJ, Uclés S, Hernando MD, Fernández-Alba AR (2011) Development of a solvent-free method for the simultaneous identification/quantification of drugs of abuse and their metabolites in environmental water by LC-MS/MS. Talanta 85:157–166

    Article  CAS  Google Scholar 

  21. Martínez C, Ramírez N, Gómez V, Pocurull E, Borrull F (2013) Simultaneous determination of 76 micropollutants in water samples by headspace solid phase microextraction and gas chromatography–mass spectrometry. Talanta 116(15):937–945

    Article  CAS  Google Scholar 

  22. Cervera MI, Beltran J, Lopez FJ, Hernandez F (2011) Determination of volatile organic compounds in water by headspace solid-phase microextraction gas chromatography coupled to tandem mass spectrometry with triple quadrupole analyzer. Anal Chim Acta 704(1–2):87–97

    Article  CAS  Google Scholar 

  23. Araujo L, Wild J, Villa N, Camargo N, Cubillan D, Prieto A (2008) Determination of anti-inflammatory drugs in water samples, by in situ derivatization, solid phase microextraction and gas chromatography-mass spectrometry. Talanta 75(1):111–115

    Article  CAS  Google Scholar 

  24. Vallecillos L, Borrull F, Pocurull E (2013) An automated headspace solid-phase microextraction followed by gas chromatography-mass spectrometry method to determine macrocyclic musk fragrances in wastewater samples. Anal Bioanal Chem 405(29):9547–9554

    Article  CAS  Google Scholar 

  25. Carpinteiro I, Abuín B, Rodríguez I, Cela R, Ramil M (2010) Headspace solid-phase microextraction followed by gas chromatography tandem mass spectrometry for the sensitive determination of benzotriazole UV stabilizers in water samples. Anal Bioanal Chem 397(2):829–839

    Article  CAS  Google Scholar 

  26. Klontza EE, Koukouraki EE, Diamadopoulos E (2010) Determination of nonylphenol ethoxylates in wastewater samples with SPME/GC-MS. Desalin Water Treat 23(1–3):80–88

    Article  CAS  Google Scholar 

  27. Tan BLL, Hawker DW, Müller J, Tremblay LA, Chapman HF (2008) Stir bar sorptive extraction and trace analysis of selected endocrine disruptors in water, biosolids and sludge samples by thermal desorption with gas chromatography-mass spectrometry. Water Res 42(1–2):404–412

    Article  CAS  Google Scholar 

  28. Gilart N, Miralles N, Marcé RM, Borrull F, Fontanals N (2013) Novel coatings for stir bar sorptive extraction to determine pharmaceuticals and personal care products in environmental waters by liquid chromatography and tandem mass spectrometry. Anal Chim Acta 774:51–60

    Article  CAS  Google Scholar 

  29. Gilart N, Cormack PAG, Marcé RM, Borrull F, Fontanals N (2013) Preparation of a polar monolithic coating for stir bar sorptive extraction of emerging contaminants from wastewaters. J Chromatogr A 1295:42–47

    Article  CAS  Google Scholar 

  30. López-Nogueroles M, Chisvert A, Salvador A, Carretero A (2011) Dispersive liquid–liquid microextraction followed by gas chromatography–mass spectrometry for the determination of nitro musks in surface water and wastewater samples. Talanta 85:1990–1995

    Article  CAS  Google Scholar 

  31. Cortada C, Costa dos Reis L, Vidal L, Llorca J, Canals A (2014) Determination of cyclic and linear siloxanes in wastewater samples by ultrasound-assisted dispersive liquid–liquid microextraction followed by gas chromatography–mass spectrometry. Talanta 120:191–197

    Article  CAS  Google Scholar 

  32. Rodriguez-Mozaz S, Lopez de Alda MJ, Barceló D (2007) Advantages and limitations of on-line solid phase extraction coupled to liquid chromatography–mass spectrometry technologies versus biosensors for monitoring of emerging contaminants in water. J Chromatogr A 1152:97–115

    Article  CAS  Google Scholar 

  33. Busetti F, Backe WJ, Bendixen N, Maier U, Place B, Giger W, Field JA (2012) Trace analysis of environmental matrices by large-volume injection and liquid chromatography–mass spectrometry. Anal Bioanal Chem 402(1):175–186

    Article  CAS  Google Scholar 

  34. Baltussen E, Sandra P, David F, Cramers C (1999) Stir bar sorptive extraction (SBSE), a novel extraction technique for aqueous samples: theory and principles. J Microcolumn Sep 11:737–747

    Article  CAS  Google Scholar 

  35. Spietelun A, Kloskowski A, Chrzanowski W, Namieśnik J (2013) Understanding solid-phase microextraction: key factors influencing the extraction process and trends in improving the technique. Chem Rev 113(3):1667–1685

    Article  CAS  Google Scholar 

  36. Canosa P, Rodríguez I, Rubí E, Bollaín MH, Cela R (2006) Optimisation of a solid-phase microextraction method for the determination of parabens in water samples at the low ng per litre level. J Chromatogr A 1124:3–10

    Article  CAS  Google Scholar 

  37. Robles-Molina J, Gilbert-López B, García-Reyes JF, Molina-Díaz A (2013) Comparative evaluation of liquid-liquid extraction, solid-phase extraction and solid-phase microextraction for the gas chromatography-mass spectrometry determination of multiclass priority organic contaminants in wastewater. Talanta 117:382–391

    Article  CAS  Google Scholar 

  38. Rodil R, Moeder M (2008) Stir bar sorptive extraction coupled to thermodesorption-gas chromatography-mass spectrometry for the determination of insect repelling substances in water samples. J Chromatogr A 1178(1–2):9–16

    Article  CAS  Google Scholar 

  39. Nallanthigal SC, Herrera S, Gómez MJ, Fernández-Alba AR (2014) Determination of hormonally active chlorinated chemicals in waters at sub μg/L level using stir bar sorptive extraction-liquid desorption followed by negative chemical ionization-gas chromatography triple quadrupole mass spectrometry. Int J Environ Anal Chem 94(1):48–64

    Article  CAS  Google Scholar 

  40. Bratkowska D, Marcé RM, Cormack PAG, Borrull F, Fontanals N (2011) Development and application of a polar coating for stir bar sorptive extraction of emerging pollutants from environmental water sample. Anal Chim Acta 706:135–142

    Article  CAS  Google Scholar 

  41. Bratkowska D, Fontanals N, Cormack PAG, Borrull F, Marcé RM (2012) Preparation of a polar monolithic stir bar based on methacrylic acid and divinylbenzene for the sorptive extraction of polar pharmaceuticals from complex water samples. J Chromatogr A 1225:1–7

    Article  CAS  Google Scholar 

  42. Gilart N, Marcé RM, Borrull F, Fontanals N (2014) New coatings for stir-bar sorptive extraction of polar emerging organic contaminants. Trends Anal Chem 54:11–23

    Article  CAS  Google Scholar 

  43. Mahugo-Santana C, Sosa-Ferrera Z, Torres-Padron ME, Santana-Rodríguez JJ (2011) Application of new approaches to liquid-phase microextraction for the determination of emerging pollutants. Trends Anal Chem 30(5):731–748

    Article  CAS  Google Scholar 

  44. Rosal R, Rodríguez A, Perdigón-Melón JA, Petre A, García-Calvo E, Gómez MJ, Agüera A, Fernández-Alba AR (2010) Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Res 44:578–588

    Article  CAS  Google Scholar 

  45. Prieto-Rodríguez L, Oller I, Klamerth N, Agüera A, Rodríguez EM, Malato S (2013) Application of solar AOPs and ozonation for elimination of micropollutants in municipal wastewater treatment plant effluents. Water Res 47(4):1521–1528

    Article  CAS  Google Scholar 

  46. Martínez Bueno MJ, Ulaszewska MM, Gomez MJ, Hernando MD, Fernández-Alba AR (2012) Simultaneous measurement in mass and mass/mass mode for accurate qualitative and quantitative screening analysis of pharmaceuticals in river water. J Chromatogr A 1256:80–88

    Article  CAS  Google Scholar 

  47. Bijlsma L, Emke E, Hernández F, de Voogt P (2013) Performance of the linear ion trap Orbitrap mass analyzer for qualitative and quantitative analysis of drugs of abuse and relevant metabolites in sewage water. Anal Chim Acta 768:102–110

    Article  CAS  Google Scholar 

  48. Furey A, Moriarty M, Bane V, Kinsella B, Lehane M (2013) Ion suppression: a critical review on causes, evaluation, prevention and applications. Talanta 115:104–122

    Article  CAS  Google Scholar 

  49. Panditi VR, Batchu SR, Gardinali PR (2013) Online solid-phase extraction-liquid chromatography-electrospray-tandem mass spectrometry determination of multiple classes of antibiotics in environmental and treated waters. Anal Bioanal Chem 405(18):5953–5964

    Article  CAS  Google Scholar 

  50. Ibáñez M, Gracia-Lor E, Bijlsma L, Morales E, Pastor L, Hernández F (2013) Removal of emerging contaminants in sewage water subjected to advanced oxidation with ozone. J Hazard Mater 260:389–398

    Article  CAS  Google Scholar 

  51. Krauss M, Singer H, Hollender J (2010) LC-high resolution MS in environmental analysis: from target screening to the identification of unknowns. Anal Bioanal Chem 397:943–951

    Article  CAS  Google Scholar 

  52. Hug C, Ulrich N, Schulze T, Brack W, Krauss M (2014) Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening. Environ Pollut 184:25–32

    Article  CAS  Google Scholar 

  53. Schymanski EL, Singer HP, Longrée P, Loos M, Ruff M, Stravs MA, Ripollés Vidal C, Hollender J (2014) Strategies to characterize polar organic contamination in wastewater: exploring the capability of high resolution mass spectrometry. Environ Sci Technol 48:1811–1818

    Article  CAS  Google Scholar 

  54. Konstantinou IK, Antonopoulou M, Lambropoulou DA (2014) In: Lambropoulou DA, Nollet LMN (eds) Transformation products of emerging contaminants in the environment. Wiley, Chichester

    Google Scholar 

  55. Agüera A, Gómez-Ramos MM, Fernandez-Alba AR (2012) Chemical evaluation of water treatment processes by LC–(Q)TOF-MS: identification of transformation products. In: Fernandez-Alba AR (ed) TOF-MS within food and environmental analysis, vol 58, Comprehensive analytical chemistry. Elsevier, Amsterdam, pp 217–272

    Chapter  Google Scholar 

  56. García-Reyes JF, Molina-Díaz A, Fernández-Alba AR (2007) Identification of pesticide transformation products in food by liquid chromatography/time-of-flight mass spectrometry via “fragmentation-degradation” relationships. Anal Chem 79:307–321

    Article  CAS  Google Scholar 

  57. Gao J, Ellis LBM, Wackett LP (2010) The university of Minnesota biocatalysis/biodegradation database: improving public access. Nucleic Acids Res 38:D488–D491

    Article  CAS  Google Scholar 

  58. EU (1991) Council directive concerning domestic wastewater treatment, 91/271 EC of May 21, 1991. J Eur Commun L135/40, May 30, 1991, Luxembourg

    Google Scholar 

  59. EU (2000) Council directive of 23 October 2002, Establishing a framework for community action in the field of water policy, 2000/60/EC. J Eur Commun L327, 22 Dec, 2000, Luxembourg

    Google Scholar 

  60. European Commission (2003) Economics and the environment: the implementation challenge of the 21 water framework directive – WATECO: a guidance document. EC, Brussels

    Google Scholar 

  61. Fatta-Kassinos D, Kalavrouziotis IK, Koukoulakis PH, Vasquez MI (2011) The risks associated with wastewater reuse and xenobiotics in the agroecological environment. Sci Total Environ 409:3555–3563

    Article  CAS  Google Scholar 

  62. Fatta-Kassinos D, Michael C (2013) Wastewater reuse applications and contaminants of emerging concern. Environ Sci Pollut Res 20:3493–3495

    Article  CAS  Google Scholar 

  63. Martínez-Carballo E, González-oreiro C, Scharf S, Gans O (2007) Environmental monitoring study of selected veterinary antibiotics in animal manure and soils in Austria. Environ Pollut 148:570–579

    Article  CAS  Google Scholar 

  64. Li Y-W, Wu X-L, Mo C-H, Tai Y-P, Huang X-P, Xiang L (2011) Investigation of sulfonamide, tetracycline, and quinolone antibiotics in vegetable farmland soil in the pearl river delta area, Southern China. J Agric Food Chem 59:7268–7276

    Article  CAS  Google Scholar 

  65. Hawker DW, Cropp R, Boonsaner M (2013) Uptake of zwitterionic antibiotics by rice (Oryza sativa L.) in contaminated soil. J Hazard Mater 263:458–466

    Article  CAS  Google Scholar 

  66. Chen F, Ying G-G, Kong L-X, Wang L, Zhao J-L, Zhou L-J, Zhang L-J (2011) Distribution and accumulation of endocrine-disrupting chemicals and pharmaceuticals in wastewater irrigated soils in Hebei, China. Environ Pollut 159:1490–1498

    Article  CAS  Google Scholar 

  67. Golet EM, Strehler A, Alder AC, Giger W (2002) Determination of fluoroquinolone antibacterial agents in sewage sludge and sludge-treated soil using accelerated solvent extraction followed by solid-phase extraction. Anal Chem 74:5455–5462

    Article  CAS  Google Scholar 

  68. Tadeo JL, Sánchez-Brunete C, Albero B, García-Valcárcel AI, Pérez RA (2012) Analysis of emerging organic contaminants in environmental solid samples. Cent Eur J Chem 10:480–520

    Article  Google Scholar 

  69. Vazquez-Roig P, Segarra R, Blasco C, Andreu V, Picó Y (2010) Determination of pharmaceuticals in soils and sediments by pressurized liquid extraction and liquid chromatography tandem mass spectrometry. J Chromatogr A 1217(16):2471–2483

    Article  CAS  Google Scholar 

  70. Hamscher G, Sczesny S, Hoper H, Nau H (2002) Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Anal Chem 74:1509–1518

    Article  CAS  Google Scholar 

  71. Uslu MÖ, Yediler A, Balcioğlu IA, Schulte-Hostede S (2008) Analysis and sorption behavior of fluoroquinolones in solid matrices. Water Air Soil Pollut 190:55–63

    Article  CAS  Google Scholar 

  72. Rice SL, Mitra S (2007) Microwave-assisted solvent extraction of solid matrices and subsequent detection of pharmaceuticals and personal care products (PPCPs) using gas chromatography-mass spectrometry. Anal Chim Acta 589:125–132

    Article  CAS  Google Scholar 

  73. Chen WLS, Jiao W, Wang M, Chang AC (2013) Reclaimed water: a safe irrigation water source? Environ Dev 8(1):74–83

    Article  Google Scholar 

  74. Turiel E, Martín-Esteban A, Tadeo JL (2006) Multiresidue analysis of quinolones and fluoroquinolones in soil by ultrasonic-assisted extraction in small columns and HPLC-UV. Anal Chim Acta 562:30–35

    Article  CAS  Google Scholar 

  75. Azzouz A, Ballesteros E (2012) Combined microwave-assisted extraction and continuous solid-phase extraction prior to gas chromatography-mass spectrometry determination of pharmaceuticals, personal care products and hormones in soils, sediments and sludge. Sci Total Environ 419:208–215

    Article  CAS  Google Scholar 

  76. Dodgen LK, Li J, Parker D, Gan JJ (2013) Uptake and accumulation of four PPCP/EDCs in two leafy vegetables. Environ Pollut 182:150–156

    Article  CAS  Google Scholar 

  77. Chen F, Ying GG, Yang JF, Zhao JL, Wang L (2010) Rapid resolution liquid chromatography-tandem mass spectrometry method for the determination of endocrine disrupting chemicals (EDCs), pharmaceuticals and personal care products (PPCPs) in wastewater irrigated soils. J Environ Sci Health B 45(7):682–693

    Article  CAS  Google Scholar 

  78. Löffler D, Ternes TA (2003) Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry. J Chromatogr A 1021:133–144

    Article  CAS  Google Scholar 

  79. Schlusener MP, Spiteller M, Bester K (2003) Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A 1003:21–28

    Article  CAS  Google Scholar 

  80. Stevens J, Kim SY, Adhikari S, Vadapalli V, Venables BJ (2009) Effects of triclosan on seed germination and seedling development of three wetland plants: Sesbania herbacea, Eclipta prostrata, and Bidens frondosa. Environ Toxicol Chem 28:2598–2609

    Article  CAS  Google Scholar 

  81. Li WC (2014) Occurrence, sources, and fate of pharmaceuticals in aquatic environment and soil. Environ Pollut 187:193–201

    Article  CAS  Google Scholar 

  82. Carlson JC, Mabury SA (2006) Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. Environ Toxicol Chem 25:1–10

    Article  CAS  Google Scholar 

  83. Ternes TA, Bonerz M, Herrmann N, Teiser B, Andersen HR (2007) Irrigation of treated wastewater in Braunschweig, Germany: an option to remove pharmaceuticals and musk fragrances. Chemosphere 66:894–904

    Article  CAS  Google Scholar 

  84. Xu J, Wu L, Chang AC (2009) Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils. Chemosphere 77(10):1299–1305

    Article  CAS  Google Scholar 

  85. Krogh KA, Mogensen BB, Halling-Sørensen B, Cortés A, Vejrup KV, Barceló D (2003) Analysis of alcohol ethoxylates and alkylamine ethoxylates in agricultural soils using pressurized liquid extraction and liquid chromatography-mass spectrometry. Anal Bioanal Chem 376:1089–1097

    Article  CAS  Google Scholar 

  86. Jiménez-Díaz I, Ballesteros O, Zafra-Gómez A, Crovetto G, Vílchez JL, Navalón A, Verge C, de Ferrer JA (2010) New sample treatment for the determination of alkylphenols and alkylphenol ethoxylates in agricultural soils. Chemosphere 80:248–255

    Article  CAS  Google Scholar 

  87. Sánchez-Brunete C, Miguel E, Albero B, Tadeo JL (2011) Analysis of salicylate and benzophenone-type UV filters in soils and sediments by simultaneous extraction cleanup and gas chromatography-mass spectrometry. J Chromatogr A 1218:4291–4298

    Article  CAS  Google Scholar 

  88. Jeon HK, Chung Y, Ryu JC (2006) Simultaneous determination of benzophenone-type UV filters in water and soil by gas chromatography-mass spectrometry. J Chromatogr A 1131:192–202

    Article  CAS  Google Scholar 

  89. Nuñez L, Tadeo JL, Garcia-Valcarcel AI, Turiel E (2008) Determination of parabens in environmental solid samples by ultrasonic-assisted extraction and liquid chromatography with triple quadrupole mass spectrometry. J Chromatogr A 1214:178–182

    Article  CAS  Google Scholar 

  90. Nuñez L, Turiel E, Martín-Esteban A, Tadeo JL (2010) Molecularly imprinted polymer for the extraction of parabens from environmental solid samples prior to their determination by high performance liquid chromatography-ultraviolet detection. Talanta 80:1782–1788

    Article  CAS  Google Scholar 

  91. Difrancesco AM, Chiu PC, Standley LJ, Allen HE, Salvito DT (2004) Dissipation of fragrance materials in sludge-amended soils. Environ Sci Technol 38:194–201

    Article  CAS  Google Scholar 

  92. Zhang Z, Rhind SM, Kerr C, Osprey M, Kyle CE (2011) Selective pressurized liquid extraction of estrogenic compounds in soil and analysis by gas chromatography-mass spectrometry. Anal Chim Acta 685(1):29–35

    Article  CAS  Google Scholar 

  93. Karnjanapiboonwong A, Suski JG, Shah AA, Cai Q, Morse AN, Anderson TA (2011) Occurrence of PPCPs at a wastewater treatment plant and in soil and groundwater at a land application site. Water Air Soil Pollut 216(1–4):257–273

    Article  CAS  Google Scholar 

  94. Bak SA, Hansen M, Pedersen KM, Halling-Sørensen B, Björklund E (2013) Quantification of four ionophores in soil, sediment and manure using pressurised liquid extraction. J Chromatogr A 1307:27–33

    Article  CAS  Google Scholar 

  95. Andreu V, Ferrer E, Rubio JL, Font G, Picó Y (2007) Quantitative determination of octylphenol, nonylphenol, alkylphenol ethoxylates and alcohol ethoxylates by pressurized liquid extraction and liquid chromatography-mass spectrometry in soils treated with sewage sludges. Sci Total Environ 378(1–2):124–129

    Article  CAS  Google Scholar 

  96. Wu X, Conkle JL, Gan J (2012) Multi-residue determination of pharmaceutical and personal care products in vegetables. J Chromatogr A 1254:78–86

    Article  CAS  Google Scholar 

  97. Schmidt CK, Lange FT, Brauch H-J (2007) Characteristics and evaluation of natural attenuation processes for organic micropollutant removal during riverbank filtration. Water Sci Technol 7(3):1–7

    CAS  Google Scholar 

  98. Tobiszewski M, Mechlińska A, Zygmunt B, Namieśnik J (2009) Trends Analyt Chem 28(8):943–951

    Article  CAS  Google Scholar 

  99. Wu C, Spongberg AL, Witter JD, Fang M, Ames A, Czajkowski KP (2010) Detection of pharmaceuticals and personal care products in agricultural soils receiving biosolids application. Clean Soil Air Water 38:230–237

    Article  CAS  Google Scholar 

  100. Kinney CA, Furlong ET, Werner SL, Cahill JD (2006) Presence and distribution of wastewater-derived pharmaceuticals in soil irrigated with reclaimed water. Environ Toxicol Chem 25:317–326

    Article  CAS  Google Scholar 

  101. Lozano N, Rice C, Ramirez M, Torrents A (2010) Fate of triclosan in agricultural soils after biosolid applications. Chemosphere 78:760–766

    Article  CAS  Google Scholar 

  102. Jacobsen AM, Halling-Sørensen B, Ingerslev F, Hansen SH (2004) Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography-tandem mass spectrometry. J Chromatogr A 1038(1–2):157–170

    Article  CAS  Google Scholar 

  103. García-Galán MJ, Díaz-Cruz S, Barceló D (2013) Multiresidue trace analysis of sulfonamide antibiotics and their metabolites in soils and sewage sludge by pressurized liquid extraction followed by liquid chromatography-electrospray-quadrupole linear ion trap mass spectrometry. J Chromatogr A 1275:32–40

    Article  CAS  Google Scholar 

  104. Madej K (2009) Microwave-assisted and cloud-point extraction in determination of drugs and other bioactive compounds. Trends Anal Chem 28(4):436–446

    Article  CAS  Google Scholar 

  105. Xu J, Wu L, Chen W, Chang AC (2008) Simultaneous determination of pharmaceuticals, endocrine disrupting compounds and hormone in soils by gas chromatography–mass spectrometry. J Chromatogr A 1202(2):189–195

    Article  CAS  Google Scholar 

  106. Chen L, Zeng Q, Wang H, Su R, Xu Y, Zhang X et al (2009) On-line coupling of dynamic microwave-assisted extraction to solid-phase extraction for the determination of sulfonamide antibiotics in soil. Anal Chim Acta 648:200–206

    Article  CAS  Google Scholar 

  107. Chenxi W, Sponberg AL, Witter JD (2008) Determination of the persistence of pharmaceuticals in biosolids using liquid-chromatography tandem mass spectrometry. Chemosphere 73:511–518

    Article  CAS  Google Scholar 

  108. Fang Y, Karnjanapiboonwong A, Chase DA, Wang J, Morse AN, Anderson TA (2012) Occurrence, fate and persistence of gemfibrozil in water and soil. Environ Toxicol Chem 31(3):550–555

    Article  CAS  Google Scholar 

  109. Chase DA, Karnjanapiboonwong A, Fang Y, Cobb GP, Morse AN, Anderson TA (2012) Occurrence of synthetic musk fragrances in effluent and non-effluent impacted environments. Sci Total Environ 416:253–260

    Article  CAS  Google Scholar 

  110. Kinney CA (2008) Bioaccumulation of pharmaceuticals and other anthropogenic waste indicators in earthworms from agricultural soil amended with biosolid or swine manure. Environ Sci Technol 42:1863–1870

    Article  CAS  Google Scholar 

  111. Gibson R, Durán-Álvarez JC, Estrada KL, Chávez A, Jiménez Cisneros B (2010) Accumulation and leaching potential of some pharmaceuticals and potential endocrine disruptors in soils irrigated with wastewater in the Tula Valley, Mexico. Chemosphere 81:1437–1445

    Article  CAS  Google Scholar 

  112. Wu CX, Spongberg AL, Witter JD, Fang M, Czajkowski KP (2010) Uptake of pharmaceutical and personal care products by soybean plants from soils applied with biosolids and irrigated with contaminated water. Environ Sci Technol 44:6157–6161

    Article  CAS  Google Scholar 

  113. Ho YB, Zakaria MP, Latif PA, Saari N (2012) Simultaneous determination of veterinary antibiotics and hormone in broiler manure, soil and manure compost by liquid chromatography-tandem mass spectrometry. J Chromatogr A 1262:160–168

    Article  CAS  Google Scholar 

  114. Siemens J, Huschek G, Siebe C, Kaupenjohann M (2010) Concentrations and mobility of human pharmaceuticals in the world’s largest wastewater irrigation system, Mexico City-Mezquital Valley. Water Res 42:2124–2134

    Article  CAS  Google Scholar 

  115. Heberer T, Adam M (2004) Transport and attenuation of pharmaceutical residues during artificial groundwater replenishment. Environ Chem 1:22–25

    Article  CAS  Google Scholar 

  116. Massmann G, Greskowiak J, Dunnbier U, Zuehlke S, Knappe A, Pekdeger A (2006) The impact of variable temperatures on the redox conditions and the behaviour of pharmaceutical residues during artificial recharge. J Hydrol 328:141–156

    Article  CAS  Google Scholar 

  117. Massmann G, Dünnbier U, Heberer T, Taute T (2008) Behaviour and redox sensitivity of pharmaceutical residues during bank filtration - Investigation of residues of phenazone-type analgesics. Chemosphere 71:1476–1485

    Article  CAS  Google Scholar 

  118. Drewes JE, Heberer Rauch T, Reddersen K (2003) Fate of pharmaceuticals during ground water recharge. Ground Water Monit Remediat 23:64–72

    Article  CAS  Google Scholar 

  119. Yao Y, Gao B, Chen H, Jiang L, Inyang M, Zimmerman AR, Cao X, Yang L, Xue Y, Li H (2012) Adsorption of sulfamethoxazole on biochar and its impact on reclaimed water irrigation. J Hazard Mater 209–210:408–413

    Article  CAS  Google Scholar 

  120. Calderón-Preciado D, Jiménez-Cartagena C, Peñuela G, Bayona JM (2009) Development of an analytical procedure for the determination of emerging and priority organic pollutants in leafy vegetables by pressurized solvent extraction followed by GC-MS determination. Anal Bioanal Chem 394(5):1319–1327

    Article  CAS  Google Scholar 

  121. Calderón-Preciado D, Matamoros V, Bayona JM (2011) Occurrence and potential crop uptake of emerging contaminants and related compounds in an agricultural irrigation network. Sci Total Environ 412–413:14–19

    Article  CAS  Google Scholar 

  122. Boxall ABA, Johnson P, Smith EJ, Sinclair CJ, Stutt E, Levy LS (2006) Uptake of veterinary medicines from soils into plants. J Agric Food Chem 54(6):2288–2297

    Article  CAS  Google Scholar 

  123. Eggen T, Asp TN, Grave K, Hormazabal V (2011) Uptake and translocation of metformin, ciprofloxacin and narasin in forage- and crop plants. Chemosphere 85(1):26–33

    Article  CAS  Google Scholar 

  124. Eggen T, Heimstad ES, Stuanes AO, Norli HR (2013) Uptake and translocation of organophosphates and other emerging contaminants in food and forage crops. Environ Sci Pollut Res 20(7):4520–4531

    Article  CAS  Google Scholar 

  125. Carvalho PN, Basto MCP, Almeida CMR, Brix H (2014) A review of plant-pharmaceutical interactions: from uptake and effects in crop plants to phytoremediation in constructed wetlands. Environ Sci Pollut Res 21(20):11729–11763

    Article  Google Scholar 

  126. McCutcheon SC, Schnoor JL (2003) Phytoremediation: transformation and control of contaminants. Wiley Inter-Science, Hoboken

    Book  Google Scholar 

  127. Trapp S, McFarlane JC (1994) Plant contamination: modelling and simulation or organic chemical processes, 1st edn. CRC Press, London, p 272

    Google Scholar 

  128. Eggen T, Lillo C (2012) Antidiabetic II drug metformin in plants: uptake and translocation to edible parts of cereals, oily seeds, beans, tomato, squash, carrots, and potatoes. J Agric Food Chem 60(28):6929–6935

    Article  CAS  Google Scholar 

  129. Macherius A, Eggen T, Lorenz W, Reemtsma T, Winkler U, Moeder M (2012) Uptake of galaxolide, tonalide, and triclosan by carrot, barley, and meadow fescue plants. J Agric Food Chem 60(32):7785–7791

    Article  CAS  Google Scholar 

  130. Mathews S, Reinhold D (2013) Biosolid-borne tetracyclines and sulfonamides in plants. Environ Sci Pollut Res Int 20:4327–4338

    Article  CAS  Google Scholar 

  131. Karnjanapiboonwong A, Chase DA, Cañas JE, Jackson WA, Maul JD, Morse AN, Anderson TA (2011) Uptake of 17α-ethynylestradiol and triclosan in pinto bean, Phaseolus vulgaris. Ecotoxicol Environ Saf 74(5):1336–1342

    Article  CAS  Google Scholar 

  132. Migliore L, Cozzolino S, Fiori M (2003) Phytotoxicity to and uptake of enrofloxacin in crop plants. Chemosphere 52:1233–1244

    Article  CAS  Google Scholar 

  133. Kumar K, Gupta SC, Baidoo SK, Chander Y, Rosen CJ (2005) Antibiotic uptake by plants from soil fertilized with animal manure. J Environ Qual 34:2082–2085

    Article  CAS  Google Scholar 

  134. Dolliver H, Kumar K, Gupta S (2007) Sulfamethazine uptake by plants from manure-amended soil. J Environ Qual 36:1224–1230

    Article  CAS  Google Scholar 

  135. Lai M, Scrimshaw MD, Lester JN (2002) Biotransformation and bioconcentration of steroid estrogens by Chlorella vulgaris. Appl Environ Microbiol 68:859–864

    Article  CAS  Google Scholar 

  136. Coogan A, Edziyie RE, La Point TW, Venables BJ (2007) Algal bioaccumulation of triclocarban, triclosan, and methyl-triclosan in a North Texas wastewater treatment plant receiving stream. Chemosphere 67:1911–1918

    Article  CAS  Google Scholar 

  137. Liu K, Ying GG, Yang LH, Zhou QX (2009) Terrestrial ecotoxicological effects of the antimicrobial triclosan. Ecotoxicol Environ Saf 72:86–92

    Google Scholar 

  138. Herklotz PA, Gurung P, Vanden Heuvel B, Kinney CA (2010) Uptake of human pharmaceuticals by plants grown under hydroponic conditions. Chemosphere 78(11):1416–1421

    Article  CAS  Google Scholar 

  139. Calderón-Preciado D, Renault Q, Matamoros V, Cañameras N, Bayona JM (2012) Uptake of organic emergent contaminants in spath and lettuce: an in vitro experiment. J Agric Food Chem 60(8):2000–2007

    Article  CAS  Google Scholar 

  140. Wu X, Ernst F, Conkle JL, Gan J (2013) Comparative uptake and translocation of pharmaceutical and personal care products (PPCPs) by common vegetables. Environ Int 60:15–22

    Article  CAS  Google Scholar 

  141. Jones-Lepp TL, Sanchez CA, Moy T, Kazemi R (2010) Method development and application to determine potential plant uptake of antibiotics and other drugs in irrigated crop production systems. J Agric Food Chem 58(22):11568–11573

    Article  CAS  Google Scholar 

  142. Hernández F, Sancho JV, Ibáñez M, Abad E, Portolés T, Mattioli L (2012) Current use of high-resolution mass spectrometry in the environmental sciences. Anal Bioanal Chem 403(5):1251–1264

    Article  CAS  Google Scholar 

  143. Santiago-Morales J, Gómez MJ, Herrera-López S, Fernández-Alba AR, García-Calvo E, Rosal R (2013) Energy efficiency for the removal of non-polar pollutants during ultraviolet irradiation, visible light photocatalysis and ozonation of a wastewater effluent. Water Res 47(15):5546–5556

    Article  CAS  Google Scholar 

  144. Herrera López S, Hernando MD, Gómez MJ, Santiago-Morales J, Rosal R, Fernández-Alba AR (2013) Investigation of Galaxolide degradation products generated under oxidative and irradiation processes by liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry and comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. Rapid Commun Mass Spectrom 27(11):1237–1250

    Article  CAS  Google Scholar 

  145. Martínez Bueno MJ, Agüera A, Hernando MD, Gómez MJ, Fernández-Alba AR (2009) Evaluation of various liquid chromatography-quadrupole-linear ion trap-mass spectrometry operation modes applied to the analysis of organic pollutants in wastewaters. J Chromatogr A 1216(32):5995–6002

    Article  CAS  Google Scholar 

  146. Ferrando-Climent L, Rodriguez-Mozaz S, Barceló D (2013) Development of a UPLC-MS/MS method for the determination of ten anticancer drugs in hospital and urban wastewaters, and its application for the screening of human metabolites assisted by information-dependent acquisition tool (IDA) in sewage samples. Anal Bioanal Chem 405:5937–5952

    Article  CAS  Google Scholar 

  147. Helbling DE, Hollender J, Kohler H-PE, Singer H, Fenner K (2010) High-throughput identification of microbial transformation products of organic micropollutants. Environ Sci Technol 44(17):6621–6627

    Article  CAS  Google Scholar 

  148. Durán-Alvarez JC, Becerril-Bravo E, Silva Castro V, Jiménez B, Gibson R (2009) The analysis of a group of acidic pharmaceuticals, carbamazepine, and potential endocrine disrupting compounds in wastewater irrigated soils by gas chromatography-mass spectrometry. Talanta 78:1159–1166

    Article  CAS  Google Scholar 

  149. Pérez-Carrera E, Hansen M, León VM, Björklund E, Krogh KA, Halling-Sørensen B, González-Mazo E (2010) Multiresidue method for the determination of 32 human and veterinary pharmaceuticals in soil and sediment by pressurized-liquid extraction and LC-MS/MS. Anal Bioanal Chem 398:1173–1184

    Article  CAS  Google Scholar 

  150. Sabourin L, Duenk P, Bonte-Gelok S, Payne M, Lapen DR, Topp E (2012) Uptake of pharmaceuticals, hormones and parabens into vegetables grown in soil fertilized with municipal biosolids. Sci Total Environ 431:233–236

    Article  CAS  Google Scholar 

  151. Shenker M, Harush D, Ben-Ari J, Chefetz B (2011) Uptake of carbamazepine by cucumber plants - a case study related to irrigation with reclaimed wastewater. Chemosphere 82:905–910

    Article  CAS  Google Scholar 

  152. Yang JF, Ying GG, Zhao JL, Tao R, Su HC, Chen F (2010) Simultaneous determination of four classes of antibiotics in sediments of the Pearl Rivers using RRLC-MS/MS. Sci Total Environ 408:3424–3432

    Article  CAS  Google Scholar 

  153. Turiel E, Martín-Esteban A, Tadeo JL (2007) Molecular imprinting-based separation methods for selective analysis of fluoroquinolones in soils. J Chromatogr A 1172:97–104

    Article  CAS  Google Scholar 

  154. Gómez-Ramos MM, Pérez-Parada A, García-Reyes JF, Fernández-Alba AR, Agüera A (2011) Use of an accurate-mass database for the systematic identification of transformation products of organic contaminants in wastewater effluents. J Chromatogr A 1218:8002–8012

    Article  CAS  Google Scholar 

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Acknowledgements

This research has been co-financed by the European Union (European Social Fund – ESF) and Greek national funds through the Operational Program “Education and Lifelong Learning” of the National Strategic Reference Framework (NSRF) – Research Funding Program “Excellence II (Aristeia II)”, Research Grant, No 4199, which is gratefully appreciated. The authors would also like to thank the Cost Action “ES1403: New and emerging challenges and opportunities in wastewater reuse (NEREUS)” for support.

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Authors and Affiliations

  1. CIESOL (Solar Energy Research Center), Joint Centre of the University of Almería-CIEMAT, 04120, Almería, Spain

    Ana Agüera

  2. Environmental Pollution Control Laboratory, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece

    Dimitra Lambropoulou

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  1. Ana Agüera
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  2. Dimitra Lambropoulou
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Correspondence to Ana Agüera or Dimitra Lambropoulou .

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  1. Department of Civil and Environmental Engineering, University of Cyprus, Nicosia, Cyprus

    Despo Fatta-Kassinos

  2. Department of Biomedical, Chemical and Environmental Engineering, University of Cincinnati, Cincinnati, Ohio, USA

    Dionysios D. Dionysiou

  3. Institute of Sustainable and Environmental Chemistry, Leuphana University Lüneburg, Lüneburg, Niedersachsen, Germany

    Klaus Kümmerer

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Agüera, A., Lambropoulou, D. (2015). New Challenges for the Analytical Evaluation of Reclaimed Water and Reuse Applications. In: Fatta-Kassinos, D., Dionysiou, D., Kümmerer, K. (eds) Wastewater Reuse and Current Challenges . The Handbook of Environmental Chemistry, vol 44. Springer, Cham. https://doi.org/10.1007/698_2015_364

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