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Repeated acute kidney injury associated with Mycobacterium gordonae infection

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Abstract

Mycobacterium gordonae is a nontuberculous mycobacterium widely distributed in the environment. Although M. gordonae is not usually pathogenic and glomerular lesions due to M. gordonae are very rare, infection has been reported in both immunocompromised patients and healthy persons. We report a case of acute kidney injury (AKI) in which M. gordonae was ultimately identified as the cause. A 70-year-old man was admitted to our hospital because of fever, polyarthritis, and AKI. He was a hepatitis B virus carrier, suffered from diabetes, and had a past history of erysipelas. No causative bacteria were identified, but coexisting infection was suspected. The patient experienced remission with antibiotic therapy, but the same symptoms recurred eight times. Blood polymerase chain reaction was performed during the 7th recurrence, and M. gordonae was detected. Clarithromycin was initiated, but 2 years after initial hospitalization, the patient died due to M. gordonae infection. In this case, acute kidney injury was a consequence of infection-related glomerulonephritis due to M. gordonae. Mycobacterium is difficult to detect by routine culture methods; therefore, diagnosis remains challenging.

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Conflict of interest

None of the authors have any conflicts of interest to declare.

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Authors and Affiliations

  1. Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan

    Tomohiro Murata, Eiji Ishikawa, Takayasu Ito & Masaaki Ito

  2. Central Clinical Laboratories, Mie University Hospital, Tsu, Mie, Japan

    Akiko Nakamura

  3. Kidney Center, Suzuka Kaisei Hospital, Suzuka, Mie, Japan

    Hiroshi Matsuo & Shinsuke Nomura

  4. Tuberculosis Surveillance Center, Research Institute of Tuberculosis, Kiyose, Tokyo, Japan

    Satoshi Mitarai

Authors
  1. Tomohiro Murata
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  2. Eiji Ishikawa
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  3. Takayasu Ito
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  4. Hiroshi Matsuo
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  5. Akiko Nakamura
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  6. Satoshi Mitarai
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  7. Shinsuke Nomura
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  8. Masaaki Ito
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Correspondence to Tomohiro Murata.

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Murata, T., Ishikawa, E., Ito, T. et al. Repeated acute kidney injury associated with Mycobacterium gordonae infection. CEN Case Rep 4, 131–134 (2015). https://doi.org/10.1007/s13730-014-0154-x

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  • DOI: https://doi.org/10.1007/s13730-014-0154-x

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