Skip to main content

Advertisement

SpringerLink
Log in

Multifunctional biomolecules with roles in abiotic stress tolerance as well as nutraceutical potential

  • Review Article
  • Published:
Journal of Plant Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

Environmental challenges such as soil salinity and drought are serious threats to global food security and biodiversity, making the selection or development of stress-tolerant genotypes of crops and native plants necessary. Certain biochemical compounds synthesized by plants are directly involved in ameliorating the effects of environmental stress in characteristic ways. Further, the biochemical composition of edible parts of crops is directly related to human health, deficiencies of certain nutrients being associated with major health conditions and healthcare costs, and public awareness of functional foods also increasing. Interestingly, the unique biochemical properties of some biomolecules involved in plant stress tolerance are also associated with significant roles in human metabolism and health. This work summarises the biochemical properties and functions of four selected biomolecules with such dual significance, i.e., abscisic acid (a key hormone with roles in plant development and abiotic stress response), glycine betaine (a quaternary ammonium compound which functions as an osmoprotectant), vitamin E components (antioxidants), and phenolic compounds (antioxidants), all four also having significant nutraceutical effects.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Ahmad P, Jaleel CA, Sharma S (2010) Antioxidant defense system, lipid peroxidation, proline-metabolizing enzymes, and biochemical activities in two Morus alba genotypes subjected to NaCl stress. Russ J Plant Physiol 57:509–517

    Article  CAS  Google Scholar 

  • Al Hassan M, Martinez Fuertez M, Ramos Sanchez FJ, Vicente O, Boscaiu M (2015) Effects of salt and water stress on plant growth and on accumulation of osmolytes and antioxidant compounds in cherry tomato. Not Bot Horti Agrobot Cluj-Napoca 43:1–11

    CAS  Google Scholar 

  • Albanes D, Heinonen OP, Huttunen JK et al (1995) Effects of alpha-tocopherol and beta-carotene supplements on cancer incidence in the alpha-tocopherol beta-carotene cancer prevention study. Am J Clin Nutr 62(6 Suppl):1427S–1430S

    CAS  PubMed  Google Scholar 

  • Arts IC, Hollman PC (2005) Polyphenols and disease risk in epidemiologic studies. Am J Clin Nutr 81(1 Suppl):317S–325S

    CAS  PubMed  Google Scholar 

  • Azzi A, Stocker A (2000) Vitamin E: non-antioxidant roles. Prog Lipid Res 39:231–255

    Article  CAS  PubMed  Google Scholar 

  • Bahorun T, Luximon-Ramma A, Crozier A, Aruoma OI (2004) Total phenol, flavonoid, proanthocyanidin and vitamin C levels and antioxidant activities of Mauritian vegetables. J Sci Food Agric 84:1553–1561

    Article  CAS  Google Scholar 

  • Bajpai M, Pande A, Tewari SK, Prakash D (2005) Phenolic contents and antioxidant activity of some food and medicinal plants. Int J Food Sci Nutr 56:287–291

    Article  CAS  PubMed  Google Scholar 

  • Bao Y, Zhao R, Li F, Tang W, Han L (2010) Simultaneous expression of Spinacia oleracea chloroplast choline monooxygenase (CMO) and betaine aldehyde dehydrogenase (BADH) genes contribute to dwarfism in transgenic Lolium perenne. Plant Mol Biol Rep 29:379–388

    Article  CAS  Google Scholar 

  • Barak AJ, Beckenhauer HC, Tuma DJ (1996) Betaine, ethanol, and the liver: a review. Alcohol 13:395–398

    Article  CAS  PubMed  Google Scholar 

  • Bartoli CG, Simontacchi M, Tambussi E, Beltrano J, Montaldi E, Puntarulo S (1999) Drought and watering-dependent oxidative stress: effect on antioxidant content in Triticum aestivum L. leaves. J Exp Bot 50:375–383

    Article  CAS  Google Scholar 

  • Bassaganya-Rier J, Guri AJ, Lu P et al (2011) Abscisic acid regulates inflammation via ligand-binding domain-independent activation of peroxisome proliferator-activated receptor gamma. J Biol Chem 286:2504–2516

    Article  CAS  Google Scholar 

  • Bellotti M, Salis A, Grozio A et al (2015) Synthesis, structural characterization and effect on human granulocyte intracellular cAMP levels of abscisic acid analogs. Bioorg Med Chem 23:22–32

    Article  CAS  PubMed  Google Scholar 

  • Bodrato N, Franco L, Fresia C et al (2009) Abscisic acid activates the murine microglial cell line N9 through the second messenger cyclic ADP-ribose. J Biol Chem 284:14777–14787

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bruzzone S, Moreschi I, Usai C et al (2007) Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger. Proc Natl Acad Sci USA 104:5759–5764

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bruzzone S, Bodrato N, Usai C et al (2008) Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger. J Biol Chem 283:32188–32197

    Article  CAS  PubMed  Google Scholar 

  • Burg MB, Ferraris JD (2008) Intracellular organic osmolytes: function and regulation. J Biol Chem 283:7309–7313

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Bustamante-Rangel M, Delgado-Zamarreño MM, Sánchez-Pérez A, Carabias-Martínez R (2007) Determination of tocopherols and tocotrienols in cereals by pressurized liquid extraction-liquid chromatography-mass spectrometry. Anal Chim Acta 587:216–221

    Article  CAS  PubMed  Google Scholar 

  • Chen TH, Murata N (2011) Glycinebetaine protects plants against abiotic stress: mechanisms and biotechnological applications. Plant Cell Environ 34:1–20

    Article  PubMed  CAS  Google Scholar 

  • Chen FSC, MacTaggart M, Wang LCH, Westly JC (1988) Analysis of abscisic acid in the brains of rodents and ruminants. Agric Biol Chem 52:1273–1274

    CAS  Google Scholar 

  • Chool Boo Y, Jung J (1999) Water deficit-induced oxidative stress and antioxidative defenses in rice plants. J Plant Phys 155:255–261

    Article  Google Scholar 

  • Chunling W, Song L (2014) Functional foods and nutraceuticals: potential role in human health. In: Ghosh D, Bagchi D, Konishi T (ed) Clinical aspects of functional foods and nutraceuticals. CRC Press, New York, pp 51–76

    Google Scholar 

  • Clifford MN (2000) Chlorogenic acids and other cinnamates—nature, occurrence, dietary burden, absorption and metabolism. J Sci Food Agric 80:1033–1043

    Article  CAS  Google Scholar 

  • Craig SA (2004) Betaine in human nutrition. Am J Clin Nutr 80:539–549

    CAS  PubMed  Google Scholar 

  • Cutler SR, Rodriguez PL, Finkelstein RR, Abrams SR (2010) Abscisic acid: emergence of a core signaling network. Annu Rev Plant Biol 61:651–679

    Article  CAS  PubMed  Google Scholar 

  • Dai J, Mumper RJ (2010) Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Mol 15:7313–7352

    Article  CAS  Google Scholar 

  • De Zwart FJ, Slow S, Payne RJ, Lever M, George PM, Gerrard JA, Chambers ST (2003) Glycine betaine and glycine betaine analogues in common foods. Food Chem 83:197–204

    Article  CAS  Google Scholar 

  • Detopoulou P, Panagiotakos DB, Antonopoulou S, Pitsavos C, Stefanadis C (2008) Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study. Am J Clin Nutr 87:424–430

    CAS  PubMed  Google Scholar 

  • Dixon RA, Paiva NL (1995) Stress-induced phenylpropanoid metabolism. Plant Cell 7:1085–1097

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dixon RA, Xie DY, Sharma SB (2005) Proanthocyanidins-a final frontier in flavonoid research? New Phytol 165:9–28

    Article  CAS  PubMed  Google Scholar 

  • Duan L, Dietrich D, Ng CH, Chan PM, Bhalerao R, Bennett MJ, Dinneny JR (2013) Endodermal ABA signaling promotes lateral root quiescence during salt stress in Arabidopsis seedlings. Plant Cell 25:324–341

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Eklund M, Bauer E, Wamatu J, Mosenthin R (2005) Potential nutritional and physiological functions of betaine in livestock. Nutr Res Rev 18:31–48

    Article  CAS  PubMed  Google Scholar 

  • Falk J, Munne-Bosch S (2010) Tocochromanol functions in plants: antioxidation and beyond. J Expt Bot 61:1549–1566

    Article  CAS  Google Scholar 

  • Gamel TH, Abdel-Aal EM (2012) Phenolic acids and antioxidant properties of barley wholegrain and pearling fractions. Agric Food Sci 21:118–131

    CAS  Google Scholar 

  • Gann PH, Ma J, Giovannucci E et al (1999) Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. Cancer Res 59:1225–1230

    CAS  PubMed  Google Scholar 

  • Gey KF (1998) Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. BioFactors 7:113–174

    Article  CAS  PubMed  Google Scholar 

  • Giri J (2011) Glycinebetaine and abiotic stress tolerance in plants. Plant Sign Behav 6:1746–1751

    Article  CAS  Google Scholar 

  • Goffman FD, Thies W, Velasco L (1999) Chemotaxonomic value of tocopherols in Brassicaceae. Phytochem 50:793–798

    Article  CAS  Google Scholar 

  • Gong M, Li Y-J, Chen S-Z (1998) Abscisic acid induced thermo-tolerance in maize seedlings mediated by calcium and associated with antioxidant system. J Plant Phys 153:488–496

    Article  CAS  Google Scholar 

  • Gong X, Qi N, Wang X, Li J, Lin L (2014) A new method for determination of α-tocopherol in tropical fruits by ultra performance convergence chromatography with diode array detector. Food Ana Met 7:1572–1576

    Article  Google Scholar 

  • Graf BA, Milbury PE, Blumberg JB (2005) Flavonols, flavones, flavanones, and human health: epidemiological evidence. J Med Food 8:281–290

    Article  CAS  PubMed  Google Scholar 

  • Grusak MA, DellaPenna D (1999) Improving the nutrient composition of plants to enhance human nutrition and health. Annu Rev Plant Physiol Plant Mol Biol 50:133–161

    Article  CAS  PubMed  Google Scholar 

  • Guri AJ, Hontecillas R, Si H, Liu D, Bassaganya-Rier J (2007) Dietary abscisic acid ameliorates glucose tolerance and obesity-related inflammation in db/db mice fed high-fat diets. Clin Nutr 26:107–116

    Article  CAS  PubMed  Google Scholar 

  • Hao M, Beta T (2012) Qualitative and quantitative analysis of the major phenolic compounds as antioxidants in barley and flaxseed hulls using HPLC/MS/MS. J Sci Food Agric 92:2062–2068

    Article  CAS  PubMed  Google Scholar 

  • Hasthanasombut S, Ntui V, Supaibulwatana K, Mii M, Nakamura I (2010) Expression of Indica rice OsBADH1 gene under salinity stress in transgenic tobacco. Plant Biotech Rep 4:75–83

    Article  Google Scholar 

  • Hoque MA, Banu MN, Okuma E et al (2007) Exogenous proline and glycinebetaine increase NaCl-induced ascorbate-glutathione cycle enzyme activities, and proline improves salt tolerance more than glycinebetaine in tobacco Bright Yellow-2 suspension-cultured cells. J Plant Physiol 164:1457–1468

    Article  CAS  PubMed  Google Scholar 

  • Hosomi A, Arita M, Sato Y et al (1997) Affinity for alpha-tocopherol transfer protein as a determinant of the biological activities of vitamin E analogs. FEBS Lett 409:105–108

    Article  CAS  PubMed  Google Scholar 

  • Hu L, Hu T, Zhang X, Pang H, Fu J (2012) Exogenous glycine betaine ameliorates the adverse effect of salt stress on perennial ryegrass. J Am Soc Hort Sci 137:38–46

    CAS  Google Scholar 

  • Jabeen Z, Hussain N, Wu DZ et al (2015) Difference in physiological and biochemical responses to salt stress between Tibetan wild and cultivated barleys. Acta Physiol Plant 37:1–8

    Article  CAS  Google Scholar 

  • Jagendorf AT, Takabe T (2001) Inducers of glycinebetaine synthesis in barley. Plant Physiol 12:1827–1835

    Article  CAS  Google Scholar 

  • Jiang M, Zhang J (2001) Effect of abscisic acid on active oxygen species, antioxidative defence system and oxidative damage in leaves of maize seedlings. Plant Cell Physiol 42:1265–1273

    Article  CAS  PubMed  Google Scholar 

  • Jideani AIO, Silungwe H, Takalani T et al. (2014) Antioxidant-rich natural grain products and human health. In: Og untibeju O (ed), Antioxidant-antidiabetic agents and human health. InTech, Rijeka, Croatia, pp 167–186

    Google Scholar 

  • Joseph S, Murphy DJ, Bhave M (2015) Identification of salt tolerant Acacia species for saline land utilisation. Biol 70:174–182

    Google Scholar 

  • Kiarostami KH, Mohseni R, Saboora A (2010) Biochemical changes of Rosmarinus officinalis under salt stress. J Stress Physiol Biochem 6:114–122

    Google Scholar 

  • Kim TH, Bohmer M, Hu H, Nishimura N, Schroede JI (2010) Guard cell signal transduction network: advances in understanding abscisic acid, CO2, and Ca2+ signaling. Annu Rev Plant Biol 61:561–591

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Kornsteiner M, Wagner KH, Elmadfa I (2006) Tocopherols and total phenolics in 10 different nut types. Food Chem 98:381–387

    Article  CAS  Google Scholar 

  • Król A, Amarowicz R, Weidner S (2014) Changes in the composition of phenolic compounds and antioxidant properties of grapevine roots and leaves (Vitis vinifera L.) under continuous of long-term drought stress. Acta Physiol Plant 36:1491–1499

    Article  CAS  Google Scholar 

  • Kruk J, Jemioła-Rzemińska M, Strzałka K (1997) Plastoquinol and α-tocopherol quinol are more active than ubiquinol and α-tocopherol in inhibition of lipid peroxidation. Chem Phys Lipids 87:3–80

    Article  Google Scholar 

  • Kruse ME (2006) Role of abscisic acid, a possible new drug in cancer treatment, and its role on human chorionic gonadotrophin pathways. MSc thesis. Syddansk Universitet, Denmark

  • Lara I, Vendrell M (2000) Changes in abscisic acid levels, ethylene biosynthesis, and protein patterns during fruit maturation of ‘Granny Smith’ apples. J Am Soc Hort Sci 125:183–189

    CAS  Google Scholar 

  • Lever M, Slow S (2010) The clinical significance of betaine, an osmolyte with a key role in methyl group metabolism. Clin Biochem 43:732–744

    Article  CAS  PubMed  Google Scholar 

  • Leymarie J, Benech-Arnold RL, Farrant JM, Corbineau F (2009) Thermodormancy and ABA metabolism in barley grains. Plant Sig Behav 4:205–207

    Article  CAS  Google Scholar 

  • Li HH, Hao RL, Wu SS (2011) Occurrence, function and potential medicinal applications of the phytohormone abscisic acid in animals and humans. Biochem Pharm 82:701–712

    Article  CAS  PubMed  Google Scholar 

  • Likes R, Madl RL, Zeisel SH, Craig SAS (2007) The betaine and choline content of a whole wheat flour compared to other mill streams. J Cereal Sci 46:93–95

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lin L, Tan RX (2011) Cross-kingdom actions of phytohormones: a functional scaffold exploration. Chem Rev 111:2734–2760

    Article  CAS  PubMed  Google Scholar 

  • Magnone M, Bruzzone S, Guida L et al (2009) Abscisic acid released by human monocytes activates monocytes and vascular smooth muscle cell responses involved in atherogenesis. J Biol Chem 284:17808–17818

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Marten H, Konrad KR, Dietrich P, Roelfsema MR, Hedrich R (2007) Ca2+-dependent and -independent abscisic acid activation of plasma membrane anion channels in guard cells of Nicotiana tabacum. Plant Physiol 143:28–37

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mendoza-Wilson AM, Santacruz-Ortega H, Balandrán-Quintana RR (2011) Relationship between structure, properties, and the radical scavenging activity of morin. J Mol Struct 995:134–141

    Article  CAS  Google Scholar 

  • Miliovsky M, Svinyarov I, Prokopova E, Batovska D, Stoyanov S, Bogdanov MG (2015) Synthesis and antioxidant activity of polyhydroxylated trans-restricted 2-arylcinnamic acids. Molecules 20:2555–2575

    Article  PubMed  CAS  Google Scholar 

  • Munné-Bosch S, Alegre L (2002) The functions of tocopherols and tocotrienols in plants. Crit Rev Plant Sci 21:31–57

    Article  Google Scholar 

  • Munns R, Tester M (2008) Mechanisms of salinity tolerance. Annu Rev Plant Biol 59:651–681

    Article  CAS  PubMed  Google Scholar 

  • Murkovic M, Wiltschko D, Pfannhauser W (1997) Formation of α-tocopherolquinone and α-tocopherolquinone epoxides in plant oil. Eur J Lipid Sci Tech 99:165–169

    CAS  Google Scholar 

  • Nakashima K, Yamaguchi-Shinozaki K (2013) ABA signaling in stress-response and seed development. Plant Cell Rep 32:959–970

    Article  CAS  PubMed  Google Scholar 

  • Nambara E, Marion-Poll A (2005) Abscisic acid biosynthesis and catabolism. Annu Rev Plant Biol 56:165–185

    Article  CAS  PubMed  Google Scholar 

  • Nemhauser JL, Hong F, Chory J (2006) Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses. Cell 126:467–475

    Article  CAS  PubMed  Google Scholar 

  • Nieves M, Nieves-Cordones M, Poorter H, Simon MD (2011) Leaf nitrogen productivity is the major factor behind the growth reduction induced by long-term salt stress. Tree Physiol 31:92–101

    Article  CAS  PubMed  Google Scholar 

  • Ouahchi K, Arita M, Kayden H et al (1995) Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet 9:141–145

    Article  CAS  PubMed  Google Scholar 

  • Packer L, Weber SU, Rimbach G (2001) Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling. J Nutr 131:369S–373S

    CAS  PubMed  Google Scholar 

  • Pandey KB, Rizvi SI (2009) Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2:270–278

    Article  PubMed  PubMed Central  Google Scholar 

  • Parihar P, Singh S, Singh R, Singh V, Prasad S (2015) Effect of salinity stress on plants and its tolerance strategies: a review. Environ Sci Poll Res 22:4056–4075

    Article  CAS  Google Scholar 

  • Park JY, Ha SW, King GL (1999) The role of protein kinase C activation in the pathogenesis of diabetic vascular complications. Perit Dial Int 19(Suppl 2):S222–S227

    PubMed  Google Scholar 

  • Petridis A, Therios I, Samouris G, Koundouras S, Giannakoula A (2012) Effect of water deficit on leaf phenolic composition, gas exchange, oxidative damage and antioxidant activity of four Greek olive (Olea europaea L.) cultivars. Plant Physiol Biochem 60:1–11

    Article  CAS  PubMed  Google Scholar 

  • Quaife ML, Harris PL (1948) Chemical assay of foods for vitamin E content. Anal Chem 20:1221–1224

    Article  CAS  Google Scholar 

  • Ragaee S, Abdel-Aal E-SM, Noaman M (2006) Antioxidant activity and nutrient composition of selected cereals for food use. Food Chem 98:32–38

    Article  CAS  Google Scholar 

  • Raman SB, Rathinasabapathi B (2003) Beta-alanine N-methyltransferase of Limonium latifolium. cDNA cloning and functional expression of a novel N-methyltransferase implicated in the synthesis of the osmoprotectant beta-alanine betaine. Plant Physiol 132:1642–1651

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rhodes DA, Hanson AD (1993) Quaternary ammonium and tertiary sulfonium compounds in higher plants. Annu Rev Plant Physiol Plant Mol Biol 44:357–384

    Article  CAS  Google Scholar 

  • Rice-Evans C, Miller N, Paganga G (1997) Antioxidant properties of phenolic compounds. Trends Plant Sci 2:152–159

    Article  Google Scholar 

  • Romero P, Rodrigo MJ, Alférez F, Ballester AR, González-Candelas L, Zacarías L, Lafuente MT (2012) Unravelling molecular responses to moderate dehydration in harvested fruit of sweet orange (Citrus sinensis L. Osbeck) using a fruit-specific ABA-deficient mutant. J Expt Bot 63:2753–2767

    Article  CAS  Google Scholar 

  • Sakamoto A, Murata N (2002) The role of glycine betaine in the protection of plants from stress: clues from transgenic plants. Plant Cell Environ 25:163–171

    Article  CAS  PubMed  Google Scholar 

  • Scalbert A, Manach C, Morand C, Remesy C, Jimenez L (2005) Dietary polyphenols and the prevention of diseases. Crit Rev Food Sci Nutr 45:287–306

    Article  CAS  PubMed  Google Scholar 

  • Scarfi S, Ferraris C, Fruscione F et al (2008) Cyclic ADP-ribose-mediated expansion and stimulation of human mesenchymal stem cells by the plant hormone abscisic acid. Stem Cells 26:2855–2864

    Article  CAS  PubMed  Google Scholar 

  • Semida WM, Taha RS, Abdelhamid MT, Rady MM (2014) Foliar-applied alpha-tocopherol enhances salt-tolerance in Vicia faba L. plants grown under saline conditions. South Afr J Bot 95:24–31

    Article  CAS  Google Scholar 

  • Sen CK, Khanna S, Rink C, Roy S (2007) Tocotrienols: the emerging face of natural vitamin E. Vitam Horm 76:203–261

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Sharp RE, Poroyko V, Hejlek LG et al (2004) Root growth maintenance during water deficits: physiology to functional genomics. J Expt Bot 55:2343–2351

    Article  CAS  Google Scholar 

  • Shaw B, Thomas TH, Cooke DT (2002) Responses of sugar beet (Beta vulgaris L.) to drought and nutrient deficiency stress. Plant Growth Reg 37:77–83

    Article  CAS  Google Scholar 

  • Sheldon CC, Rouse DT, Finnegan EJ, Peacock WJ, Dennis ES (2000) The molecular basis of vernalization: the central role of flowering locus C (FLC). Proc Natl Acad Sci USA 97:3753–3758

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Shetty K, McCue P (2003) Phenolic antioxidant biosynthesis in plants for functional food application: integration of systems biology and biotechnological approaches. Food Biotech 17:67–97

    Article  CAS  Google Scholar 

  • Simpson GG, Dijkwel PP, Quesada V, Henderson I, Dean C (2003) FY is an RNA 3′ end-processing factor that interacts with FCA to control the arabidopsis floral transition. Cell 113:777–787

    Article  CAS  PubMed  Google Scholar 

  • Singh J, Upadhyay AK, Prasad K, Bahadur A, Rai M (2007) Variability of carotenes, vitamin C, E and phenolics in Brassica vegetables. J Food Compos Anal 20:106–112

    Article  CAS  Google Scholar 

  • Sturla L, Fresia C, Guida L et al (2011) Binding of abscisic acid to human LANCL2. Biochem Biophys Res Commun 415:390–395

    Article  CAS  PubMed  Google Scholar 

  • Tanaka K, Masuda R, Sugimoto T, Omasa K, Sakaki T (1990) Water deficiency-induced changes in the contents of defensive substances against active oxygen in spinach leaves. Agric Biol Chem 54:2629–2634

    CAS  Google Scholar 

  • Temel A, Gozukirmizi N (2015) Physiological and molecular changes in barley and wheat under salinity. Appl Biochem Biotechnol 175:2950–2960

    Article  CAS  PubMed  Google Scholar 

  • Thomes PG, Bligh SM, Kharbanda KK (2015) Multiple roles of betaine in protecting against alcohol- induced liver injury. In: Preedy VR (ed) Betaine: chemistry, analysis, function and effects. The Royal Society of Chemistry, London. pp 285–310

    Google Scholar 

  • Thondre PS, Ryan L, Henry CJK (2011) Barley β-glucan extracts as rich sources of polyphenols and antioxidants. Food Chem 126:72–77

    Article  CAS  Google Scholar 

  • Umezawa T, Nakashima K, Miyakawa T et al (2010) Molecular basis of the core regulatory network in ABA responses: sensing, signaling and transport. Plant Cell Physiol 51:1821–1839

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Viñas P, Bravo-Bravo M, López-García I, Pastor-Belda M, Hernández-Córdoba M (2014) Pressurized liquid extraction and dispersive liquid–liquid microextraction for determination of tocopherols and tocotrienols in plant foods by liquid chromatography with fluorescence and atmospheric pressure chemical ionization-mass spectrometry detection. Talanta 119:98–104

    Article  PubMed  CAS  Google Scholar 

  • Wani SH, Singh NB, Haribhushan A, Mir JI (2013) Compatible solute engineering in plants for abiotic stress tolerance—role of glycine betaine. Curr Genomics 14:157–165

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Waśkiewicz A, Muzolf-Panek M, Goliński P (2013) Phenolic content changes in plants under salt stress. In: Ahmad P, Azooz MM, Prasad MNV (eds) Ecophysiology and responses of plants under salt stress. Springer, New York, pp 283–314

    Chapter  Google Scholar 

  • Winkel-Shirley B (2001) Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology. Plant Physiol 126:485–493

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Wolf G (2008) Energy regulation by the skeleton. Nutr Rev 66:229–233

    Article  PubMed  Google Scholar 

  • Wyn Jones R, Storey R, Leigh RA, Ahmad N, Pollard A (1977) A hypothesis on cytoplasmic osmoregulation. In: Marrè E, Cifferi O (eds) Regulation of cell membrane activities in plants. Elsevier, Amsterdam, pp 121–136

    Google Scholar 

  • Xiao J, Suzuki M, Jiang X, Chen X, Yamamoto K, Ren F, Xu M (2008) Influence of B-ring hydroxylation on interactions of flavonols with bovine serum albumin. J Agric Food Chem 56:2350–2356

    Article  CAS  PubMed  Google Scholar 

  • Yamauchi R, Matsushita S (1977) Quenching effect of tocopherols on the methyl linoleate photooxidation and their oxidation products. Agric Biol Chem 41:1425–1430

    CAS  Google Scholar 

  • Yancey P (1994) Compatible and counteracting solutes. In: Strange K (ed) Cellular and molecular physiology of cell volume regulation. CRC Press, New York, pp 81–109

    Google Scholar 

  • Yancey PH, Somero GN (1979) Counteraction of urea destabilization of protein structure by methylamine osmoregulatory compounds of elasmobranch fishes. Biochem J 18:317–323

    Article  Google Scholar 

  • Yoon GA, Yeum KJ, Cho YS, Chen CYO, Tang G, Blumberg JB, Russell RM, Yoon S, Lee-Kim YC (2012) Carotenoids and total phenolic contents in plant foods commonly consumed in Korea. Nutr Res Pract 6:481–490

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Yu W, Simmons-Menchaca M, Gapor A, Sanders BG, Kline K (1999) Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols. Nutr Cancer 33:26–32

    Article  PubMed  Google Scholar 

  • Zeevaart JAD, Creelman RA (1988) Metabolism and physiology of abscisic acid. Annu Rev Plant Phys Plant Mol Biol 39:439–473

    Article  CAS  Google Scholar 

  • Zhang M, Yuan B, Leng P (2009) The role of ABA in triggering ethylene biosynthesis and ripening of tomato fruit. J Expt Bot 60:1579–1588

    Article  CAS  Google Scholar 

  • Zhu SQ, Chen MW, Ji BH, Jiao DM, Liang JS (2011) Roles of xanthophylls and exogenous ABA in protection against NaCl-induced photodamage in rice (Oryza sativa L) and cabbage (Brassica campestris). J Expt Bot 62:4617–4625

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Science, Engineering and Technology, Swinburne University of Technology, PO Box 218, John Street, Hawthorn, VIC, 3122, Australia

    Zaynab Derakhshani, Francois Malherbe & Mrinal Bhave

Authors
  1. Zaynab Derakhshani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Francois Malherbe
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mrinal Bhave
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Mrinal Bhave.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Derakhshani, Z., Malherbe, F. & Bhave, M. Multifunctional biomolecules with roles in abiotic stress tolerance as well as nutraceutical potential. J. Plant Biochem. Biotechnol. 26, 121–131 (2017). https://doi.org/10.1007/s13562-016-0372-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13562-016-0372-8

Keywords

Search

Navigation