Résumé
Malgré le développement d’outils diagnostiques non invasifs, la fibroscopie bronchique avec lavage bronchoalvéolaire (FB-LBA) garde toujours une place déterminante dans la quête diagnostique devant un patient admis en réanimation pour insuffisance respiratoire aiguë hypoxémiante. C’est parfois le seul examen qui permet d’apporter le diagnostic final. Elle permet aussi de mieux cibler les traitements et donc d’en réduire les effets secondaires. Pour être bénéfique au patient, la FB-LBA doit s’intégrer dans une démarche diagnostique raisonnée, être réservée à des populations ciblées et être pratiquée par des équipes entraînées. De nombreux travaux ont démontré que, sous couvert d’un certain nombre de précautions, ce geste peut être réalisé en toute sécurité même chez des patients profondément hypoxémiques et non intubés. La réalisation de la FB-LBA sous ventilation non invasive est un moyen d’en réduire le retentissement respiratoire. Certains auteurs ont également montré que l’ajout d’une sédation permet d’en améliorer la tolérance.
Abstract
Despite the development of non-invasive diagnostic tools, bronchoscopy with bronchoalveolar lavage (FB-BAL) still plays a key role in the diagnostic challenge faced while managing patients admitted to the intensive care unit with acute hypoxemic respiratory failure. FB-BAL often represents the most helpful test to assess the final diagnosis and to allow targeting treatments and reducing their side-effects. FB-BAL should be performed in selected patients by trained physicians. To be beneficial, FB-BAL should be integrated into a clear diagnostic strategy and its benefits balanced with its possible risks in the hypoxemic patients. Several studies have assessed that FB-BAL is safe even in spontaneously breathing hypoxemic patients. In these patients, non-invasive positive pressure ventilation has been shown to prevent any worsening in respiratory conditions and avoid tracheal intubation in comparison to conventional oxygen supply. Sedation was suggested to additionally improve FB-BAL safety.
Références
Azoulay E, Alberti C, Bornstain C, et al (2001) Improved survival in cancer patients requiring mechanical ventilatory support: impact of non-invasive mechanical ventilatory support. Crit Care Med: 519–525
Azoulay E, Thiéry G, Chevret S, et al (2004) The prognosis of acute respiratory failure in critically ill cancer patients. Medicine 83:360–370
Hilbert G, Gruson D, Vargas F, et al (2001) Non-invasive ventilation in immunosupressed patients with pulmonary infiltrates, fever, and acute respiratory failure. N Engl J Med 344:481–487
Murray PV, OBrien M, Padhani AR, et al (2001) Use of the first line bronchoalveolar lavage in the immunosupressed oncology patient. Bone Marrow Transplant 27:967–971
Azoulay E, Mokart D, Rabbat A, Schlemmer B (2008) Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data. Crit Care Med 36:100–107
Spanavello A, Migliori GB, Satta A, et al (1998) Bronchoalveolar lavage causes decrease in PaO2, Increase in (A-a) gradient value and bronchoconstriction in asthmatics. Respir Med 92:191–197
Bauer TT, Arosio C, Monton C, et al (2001) Systemic inflammatory response after bronchoalveolar lavage in critically ill patients. Eur Respir J 17:274–280
Pugin J, Suter PM (1992) Diagnostic bronchoalveolar lavage in patients with pneumonia produces sepsis-like systematic effects. Intensive Care Med 18:6–10
American Thoracic Society (1990) Clinical role of bronchoalveolar lavage in adults with pulmonary disease. Am Rev Respir Dis 142:481–486
Trouillet JL, Guiguet M, Gibert C, et al (1990) Fiberoptic bronchoscopy in ventilated patients. Evaluation of cardiopulmonary risk under midazolam sedation. Chest 97:927–933
Antonelli M, Conti G, Riccioni L, Meduri G (1996) Non-invasive positive pressure ventilation via face mask during bronchoscopy with BAL in high risk hypoxemic patients. Chest 110:724–728
Maitre B, Jaber S, Maggiore SM, et al (2000) Continuous positive airway pressure during fiberoptic bronchoscopy in hypoxemic patients. Am J Crit Care Med 162:1063–1067
Antonelli M, Conti G, Rocco M, et al (2002) Non-invasive positive-pressure ventilation versus conventional oxygen supplementation in hypoxemic patients undergoing diagnostic bronchoscopy. Chest 121:1149–1154
Azoulay E, Mokart D, Lambert J, et al (2010) Diagnostic strategy for hematology and oncology patients with acute respiratory failure. Am J Respir Crit Care Med 182:1038–1046
(2006) Ventilation non-invasive au cours de l’insuffisance respiratoire aiguë (nouveau-né exclu). In: 3e Conférence de consensus commune organisée par la SFAR, SPLF et la SRLF; 2006; Paris
Antonelli M, Alberto Pennisi M, Conti G, et al (2003) Fiberoptic bronchoscopy during non-invasive positive pressure ventilation delivered by helmet. Intensive Care Med 29:126–129
Heunks L, De Bruin C, Van der Hoeven J, Van der Heijden H (2010) Non-invasive mechanical ventilation for diagnostic bronchoscopy using a new fac mask: an observational feasibility study. Intensive Care Med 36:143–147
Chiner E, Sancho-Chust JN, Llombart M, et al (2010) Fiberoptic bronchoscopy during nasal non-invasive ventilation in acute respiratory failure. Respiration 80:321–326
Gonzalez R, De-la-Rosa-Ramirez I, Maldonado-Hernandez A, Dominguez-Cherit G (2003) Should by patients undergoing a bronchoscopy be sedated? Acta Anaesthesiol Scand 47:411–415
Putanati S, Ballerin J, Corbetta L (1999) Patient satisfaction with conscious sedation for bronchoscopy. Chest 115:1437–1440
Allen MB (1995) Sedation in fiberoptic bronchoscopy. BMJ 310:1333
Silvestri G, Vincent B, Wahidi M, et al (2009) A phase 3, randomized, double-blind study to assess the efficacy and safety of fospropofol disodium injection for moderate sedation in patients undergoing flexible bronchoscopy. Chest 135:41–47
Matot I, Kramer M (1997) Sedation in outpatient fiberoptic bronchoscopy: alfentanil-propofol vs meperidine-midazolam. Anesthesiology 87(Suppl 3):12 A
Maguire GP, Rubinfeld AR, Trembath PW, Pain MC (1998) Patients prefer sedation for fiberoptic bronchoscopy. Respirology 3:81–85
British Thoracic Society Interventional Bronchoscopy Guideline group (2011) British Thoracic Society guideline for advanced diagnostic and therapeutic flexible bronchoscopy in adults. Thorax 66(Suppl 3: iii):1–21
Wood-Baker R, Burdon J, MacGregor A, et al (2001) Fiber-optic bronchoscopy in adults: a position paper of the Thoracic Society of Australia new Zealand. Intern Med J 31:479–487
Clouzeau B, Bui HN, Guilhon E, et al (2011) Fiberoptic bronchoscopy under non-invasive ventilation and propofol target-controlled infusion in hypoxemic patients. Intensive Care Med 37:1965–1975
Clouzeau B, Bui HN, Vargas F, et al (2010) Target-controlled infusion of propofol for sedation in patients with non-invasive ventilation failure due to low tolerance: a preliminary study. Intensive Care Med 36:1675–1680
Hilbert G, Clouzeau B, Bui HN, Vargas F (2012) Sedation during non-invasive ventilation. Minerva Anestesiol 78:842–846
Clouzeau B, Vargas F, Boyer A, et a (2011) Place et modalités de la sédation au cours de la ventilation non-invasive. Reanimation 20:389–396
Dreher M, Ekkernkamp E, Hendrik Storre J, et al (2010) Sedation during flexible bronchoscopy in patients with preexisting respiratory failure: midazolam versus midazolam plus alfentanil. Respiration 79:307–314
Baumann H, Klose H, Simon M, et al (2011) Fiber optic bronchoscopy in patients with acute hypoxemix respiratory failure requiring non-invasive ventilation: a feasibility study. Crit Care 15:R179
Azoulay E, Mokart D, Rabbat A, et al (2008) Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data. Crit Care Med 36:100–107
Chernik DA, Gillings D, Laine H, et al (1990) Validity and reliability of the Observer’s Assessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol 10:244–251
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Clouzeau, B., Saghi, T. La fibroscopie bronchique chez le patient de réanimation hypoxémique et non intubé: modalités pratiques. Réanimation 22, 100–106 (2013). https://doi.org/10.1007/s13546-012-0535-4
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DOI: https://doi.org/10.1007/s13546-012-0535-4
Mots clés
- Fibroscopie bronchique
- Lavage bronchoalvéolaire
- Sédation
- Ventilation non invasive
- Propofol
- Sédation
- Insuffisance respiratoire aiguë