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Three-dimensional echocardiography in various types of heart disease: a comparison study of magnetic resonance imaging and 64-slice computed tomography in a real-world population

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Abstract

Background

Accurate quantification of left ventricular (LV) volumes [end-diastolic volume (EDV) and end-systolic volume (ESV)] and ejection fraction (EF) is of critical importance. The development of real-time three-dimensional echocardiography (RT3DE) has shown better correlation than two-dimensional (2D) echocardiography with magnetic resonance imaging (MRI) measurements. The aim of our study was to assess the accuracy of RT3DE and 64-slice computed tomography (CT) in the evaluation of LV volumes and function using MRI as the reference standard in a real-world population with various types of heart disease with different chamber geometry.

Methods

The study population consisted of 66 patients referred for cardiac MRI for various pathologies. All patients underwent cardiac MRI, and RT3DE and 64 slices CT were then performed on a subsequent day. The study population was then divided into 5 clinical groups depending on the underlying heart disease.

Results

RT3DE volumes correlated well with MRI values (R 2 values: 0.90 for EDV and 0.94 for ESV). RT3DE measurements of EF correlated well with MRI values (R 2 = 0.86). RT3DE measurements resulted in slightly underestimated values of both EDV and ESV, as reflected by biases of −9.18 and −4.50 mL, respectively. Comparison of RT3DE and MRI in various types of cardiomyopathies showed no statistical difference between different LV geometrical patterns.

Conclusion

These results confirm that RT3DE has good accuracy in everyday clinical practice and can be of clinical utility in all types of cardiomyopathy independently of LV geometric pattern, LV diameter or wall thickness, taking into account a slight underestimation of LV volumes and EF compared to MRI.

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Acknowledgments

The study did not receive any funding or research contracts.

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Authors and Affiliations

  1. UO Cardiologia, Maria Cecilia Hospital-GVM Care and Research, Cotignola, RA, Italy

    Angelo Squeri, Stefano Censi, Marco Baldelli & Stefano Bosi

  2. Dipartimento Cardio-Nefro-Polmonare, Azienda Ospedaliero Universitaria di Parma, Parma, Italy

    Claudio Reverberi, Nicola Gaibazzi & Simone Maurizio Binno

  3. Dipartimento di Scienze Statistiche, Università di Bologna, Bologna, Italy

    Enrico Properzi

Authors
  1. Angelo Squeri
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  2. Stefano Censi
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  3. Claudio Reverberi
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  4. Nicola Gaibazzi
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  5. Marco Baldelli
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  6. Simone Maurizio Binno
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  7. Enrico Properzi
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  8. Stefano Bosi
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Correspondence to Angelo Squeri.

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All authors declare that they have no conflict of interest.

Human rights statements and informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later revisions. Informed consent was obtained from all patients for being included in the study.

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Squeri, A., Censi, S., Reverberi, C. et al. Three-dimensional echocardiography in various types of heart disease: a comparison study of magnetic resonance imaging and 64-slice computed tomography in a real-world population . J Echocardiogr 15, 18–26 (2017). https://doi.org/10.1007/s12574-016-0315-3

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  • DOI: https://doi.org/10.1007/s12574-016-0315-3

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