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Enhanced Sensitivity of Surface Plasmon Resonance Phase-Interrogation Biosensor by Using Silver Nanoparticles

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Abstract

It is demonstrated that the sensitivity of surface plasmon resonance phase-interrogation biosensor can be enhanced by using silver nanoparticles. Silver nanoparticles were fabricated on silver films by using thermal evaporation. Sizes of silver nanoparticles on silver thin film can be tuned by controlling the deposition parameters of thermal evaporation. By using surface plasmon resonance heterodyne interferometey to measure the phase difference between the p and s polarization of incident light, we have demonstrated that sensitivity of glucose detection down to the order of 10−8 refractive index units can be obtained.

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References

  1. Raether H (1988) Surface plasmons on smooth and rough surfaces and on gratings. Springer, Berlin

    Google Scholar 

  2. Homola J (2003) Present and future of surface plasmon resonance biosensors. Anal Bioanal Chem 377:528–539

    Article  CAS  Google Scholar 

  3. Nelson SG, Johnston KS, Yee SS (1996) High sensitivity surface plasmon resonance sensor based on phase detection. Sens Actuators B 35–36:187–191

    Article  Google Scholar 

  4. Hooper IR, Sambles JR (2004) Differential ellipsometric surface plasmon resonance sensors with liquid crystal polarization modulators. Appl Phys Lett 85:3017

    Article  CAS  Google Scholar 

  5. Naraoka R, Kajikawa K (2005) Phase detection of surface plasmon resonance using rotating analyzer method. Sens Actuators B 107:952–956

    Article  Google Scholar 

  6. Patskovsky S, Maisonneuve M, Meunier M, Kabashin AV (2008) Mechanical modulation method for ultrasensitive phase measurements in photonics biosensing. Opt Express 16:21305–21314

    Article  CAS  Google Scholar 

  7. Markowicz PP, Law WC, Baev A, Prasad PN (2007) Phase-sensitive time-modulated surface Plasmon resonance polarimetry for wide dynamic range biosensing. Opt Express 15:1745–1754

    Article  CAS  Google Scholar 

  8. Kabashin AV, Patskovsky S, Grigorenko AN (2009) Phase and amplitude sensitivities in surface plasmon resonance bio and chemical sensing. Opt Express 17:21191–21204

    Article  CAS  Google Scholar 

  9. Chiang HP, Lin JL, Chen ZW (2006) High sensitivity surface plasmon resonance sensor based on phase interrogation at optimal incident wavelengths. Appl Phys Lett 88:141105

    Article  Google Scholar 

  10. Jung LS, Campbell CT, Chinowsky TM, Mar MN, Yee SS (1998) Quantitative interpretation of the response of surface plasmon resonance sensors to adsorbed films. Langmuir 14:5636–5648

    Article  CAS  Google Scholar 

  11. Chiang HP, Yeh HT, Chen CM, Wu JC, Su SY, Chang R, Wu YJ, Tsai DP, Jen SU, Leung PT (2004) Surface plasmon resonance monitoring of temperature via phase measurement. Opt Commun 241:409–418

    Article  CAS  Google Scholar 

  12. Chiang HP, Lin JL, Chang R, Su SY (2005) High-resolution angular measurement using surface-plasmon-resonance via phase interrogation at optimal incident wavelengths. Opt Lett 30:2727–2729

    Article  Google Scholar 

  13. Leung PT, Pollard-Knight D, Malan GP, Finlan MF (1994) Modelling of particle-enhanced sensitivity of the surface-plasmon resonance biosensor. Sens Actuators B 22:175–180

    Article  Google Scholar 

  14. Lyon LA, Musick MD, Smith PC, Reiss BD, Pena DJ, Natan MJ (1999) Surface plasmon resonance of colloidal Au-modified gold films. Sens Actuators B 54:118–124

    Article  Google Scholar 

  15. Gupta R, Dyer MJ, Weimer WA (2002) Preparation and characterization of surface plasmon resonance tunable gold and silver films. J Appl Phys 92:5264–5271

    Article  CAS  Google Scholar 

Download references

Acknowledgments

H.-P. Chiang acknowledges the financial support from the Center for Marine Bioenvironment and Biotechnology, National Taiwan Ocean University, and the National Science Council of ROC under grant number NSC 97-2112-M-019-001-MY3.

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Authors and Affiliations

  1. Institute of Optoelectronic Sciences, National Taiwan Ocean University, No. 2 Pei-Ning Rd, 202, Keelung, Taiwan

    Tzu-Cheih Peng, Wen-Chi Lin, Chih-Wei Chen & Hai-Pang Chiang

  2. Department of Physics, National Taiwan University, Taipei, Taiwan

    Din Ping Tsai

  3. Institute of Physics, Academia Sinica, Taipei, Taiwan

    Hai-Pang Chiang

  4. Instrument Technology Research Center, National Applied Research Laboratories, Hsinchu, Taiwan

    Din Ping Tsai & Hai-Pang Chiang

Authors
  1. Tzu-Cheih Peng
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  2. Wen-Chi Lin
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  3. Chih-Wei Chen
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  4. Din Ping Tsai
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  5. Hai-Pang Chiang
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Correspondence to Hai-Pang Chiang.

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Peng, TC., Lin, WC., Chen, CW. et al. Enhanced Sensitivity of Surface Plasmon Resonance Phase-Interrogation Biosensor by Using Silver Nanoparticles. Plasmonics 6, 29–34 (2011). https://doi.org/10.1007/s11468-010-9165-4

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  • DOI: https://doi.org/10.1007/s11468-010-9165-4

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