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Apophysomyces elegans: a novel cause of endogenous endophthalmitis in an immunocompetent individual

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Abstract

A 20-year-old male presented with sudden onset redness, pain, and decreased vision in his left eye. Best-corrected visual acuity in the left eye was noted to be perception of light positive with inaccurate projection. On clinical examination, he was diagnosed to have left eye endogenous endophthalmitis. Smear and culture of vitreous biopsy were positive for Apophysomyces elegans, a fungus known to cause extensive soft tissue infections systemically characteristically in immunocompetent individual. The patient was treated aggressively with topical, systemic, and intravitreal antifungals but had a poor visual and anatomical outcome. This is a first known report of endogenous endophthalmitis due to Apophysomyces elegans.

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References

  1. Wong JS, Chan TK, Lee HM, Chee SP (2000) Endogenous bacterial endophthalmitis: an East Asian experience and a reappraisal of a severe ocular affliction. Ophthalmology 107:1483–1491

    Article  CAS  PubMed  Google Scholar 

  2. Shrader SK, Band JD, Lauter CB, Murphy P (1990) The clinical spectrum of endophthalmitis: incidence, predisposing factors, and features influencing outcome. J Infect Dis 162:115–120

    Article  CAS  PubMed  Google Scholar 

  3. Chee SP, Jap A (2001) Endogenous endophthalmitis. Curr Opin Ophthalmol 12:464–470

    Article  CAS  PubMed  Google Scholar 

  4. Okada AA, Johnson RP, Liles WC, D’Amico DJ, Baker AS (1994) Endogenous bacterial endophthalmitis. Report of a ten-year retrospective study. Ophthalmology 101:832–838

    Article  CAS  PubMed  Google Scholar 

  5. Binder MI, Chua J, Kaiser PK (2003) Endogenous endophthalmitis: an 18-year review of culture positive cases at a tertiary care centre. Medicine 82:97–105

    Article  PubMed  Google Scholar 

  6. Kwon-Chung KJ, Bennett JE (1992) Mucormycosis. In: Cann C (ed) Medical Mycology. Lea & Febiger, Philadelphia, pp 524–559

    Google Scholar 

  7. Misra PC, Srivastava KJ, Lata K (1979) Apophysomyces, a new genus of the Mucorales. Mycotaxon 8:377–382

    Google Scholar 

  8. Wieden MA, Steinbronn KK, Padhye AA, Ajello L, Chandler FW (1985) Zygomycosis caused by Apophysomyces elegans. J Clin Microbiol 22:522–526

    CAS  PubMed Central  PubMed  Google Scholar 

  9. Liang KP, Tleyjeh MI, Wilson WR, Roberts GD, Temesgen Z (2006) Rhino-orbitocerebral mucormycosis caused by apophysomyces elegans. J Clin Microbiol 44:892–898

    Article  PubMed Central  PubMed  Google Scholar 

  10. Schutz P, Behbehani J, Khan Z, Ahmad S, Kazem M, Dhar R et al (2006) Fatal rhino-orbito-cerebral zygomycosis caused by apophysomyces elegans in a healthy patient. J Oral Maxillofac Surg 64:1795–1802

    Article  PubMed  Google Scholar 

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Correspondence to Vivek Pravin Dave.

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Dave, V.P., Sharma, S., Yogi, R. et al. Apophysomyces elegans: a novel cause of endogenous endophthalmitis in an immunocompetent individual. Int Ophthalmol 34, 1285–1289 (2014). https://doi.org/10.1007/s10792-014-9999-4

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  • DOI: https://doi.org/10.1007/s10792-014-9999-4

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