Skip to main content
SpringerLink
Log in

Cardiolipin in energy transducing membranes

  • Review
  • Published:
Biochemistry (Moscow) Aims and scope Submit manuscript

Abstract

Cardiolipin is a phospholipid located exclusively in energy transducing membranes such as the bacterial cytoplasmic membrane and the inner membrane of mitochondria. It plays both a structural and a functional role in many multimeric complexes associated with these membranes. The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Dowhan, W., Mileykovskaya, E., and Bogdanov, M. (2004) Biochim. Biophys. Acta, 1666, 19–39.

    PubMed  CAS  Google Scholar 

  2. Mikel’saar, K., Severina, I. I., and Skulachev, V. P. (1974) Usp. Sovrem. Biol., 78, 348–370.

    PubMed  CAS  Google Scholar 

  3. Zhang, M., Mileykovskaya, E., and Dowhan, W. (2002) J. Biol. Chem., 277, 43553–43556.

    PubMed  CAS  Google Scholar 

  4. Pfeiffer, K., Gohil, V., Stuart, R. A., Hunte, C., Brandt, U., Greenberg, M. L., and Schagger, H. (2003) J. Biol. Chem., 278, 52873–52880.

    PubMed  CAS  Google Scholar 

  5. Pangborn, M. (1942) J. Biol. Chem., 143, 247–256.

    CAS  Google Scholar 

  6. Schlame, M., Rua, D., and Greenberg, M. L. (2000) Progr. Lipid Res., 39, 257–288.

    CAS  Google Scholar 

  7. Gu, Z., Valianpour, F., Chen, S., Vaz, F. M., Hakkaart, G. A., Wanders, R. J., and Greenberg, M. L. (2004) Mol. Microbiol., 51, 149–158.

    PubMed  CAS  Google Scholar 

  8. Hoch, F. L. (1992) Biochim. Biophys. Acta, 1113, 71–133.

    PubMed  CAS  Google Scholar 

  9. Palsdottir, H., and Hunte, C. (2004) Biochim. Biophys. Acta, 1666,2–18.

    PubMed  CAS  Google Scholar 

  10. McAuley, K. E., Fyfe, P. K., Ridge, J. P., Isaacs, N. W., Cogdell, R. J., and Jones, M. R. (1999) Proc. Natl. Acad. Sci. USA, 96, 14706–14711.

    PubMed  CAS  Google Scholar 

  11. Yankovskaya, V., Horsefield, R., Tornroth, S., Luna-Chavez, C., Miyoshi, H., Leger, C., Byrne, B., Cecchini, G., and Iwata, S. (2003) Science, 299, 700–704.

    PubMed  CAS  Google Scholar 

  12. Lange, C., Nett, J. H., Trumpower, B. L., and Hunte, C. (2001) EMBO J., 20, 6591–6600.

    PubMed  CAS  Google Scholar 

  13. Jormakka, M., Byrne, B., and Iwata, S. (2003) Curr. Opin. Struct. Biol., 13, 418–423.

    PubMed  CAS  Google Scholar 

  14. Sedlak, E., and Robinson, N. C. (1999) Biochemistry, 38, 14966–14972.

    PubMed  CAS  Google Scholar 

  15. Beyer, K., and Klingenberg, M. (1985) Biochemistry, 24, 3821–3826.

    PubMed  CAS  Google Scholar 

  16. Wakeham, M. C., Sessions, R. B., Jones, M. R., and Fyfe, P. K. (2001) Biophys. J., 80, 1395–1405.

    Article  PubMed  CAS  Google Scholar 

  17. Katona, G., Andreasson, U., Landau, E. M., Andreasson, L. E., and Neutze, R. (2003) J. Mol. Biol., 331, 681–692.

    PubMed  CAS  Google Scholar 

  18. Chance, B., and Williams, G. R. (1955) Nature, 176, 250–254.

    PubMed  CAS  Google Scholar 

  19. Hackenbrock, C. R., Chazotte, B., and Gupte, S. S. (1986) J. Bioenerg. Biomembr., 18, 331–368.

    PubMed  CAS  Google Scholar 

  20. Schagger, H. (2001) Crit. Rev., 52, 119–128.

    CAS  Google Scholar 

  21. Krause, F., Scheckhuber, C. Q., Werner, A., Rexroth, S., Reifschneider, N. H., Dencher, N. A., and Osiewacz, H. D. (2004) J. Biol. Chem., 279, 26453–26461.

    PubMed  CAS  Google Scholar 

  22. Schagger, H., and Pfeiffer, K. (2000) EMBO J., 19, 1777–1783.

    PubMed  CAS  Google Scholar 

  23. Cruciat, C. M., Brunner, S., Baumann, F., Neupert, W., and Stuart, R. A. (2000) J. Biol. Chem., 275, 18093–18098.

    PubMed  CAS  Google Scholar 

  24. Boumans, H., Grivell, L. A., and Berden, J. A. (1998) J. Biol. Chem., 273, 4872–4877.

    PubMed  CAS  Google Scholar 

  25. Hunte, C., Koepke, J., Lange, C., Rossmanith, T., and Michel, H. (2000) Struct. Fold. Des., 8, 669–684.

    CAS  Google Scholar 

  26. Taanman, J. W., and Capaldi, R. A. (1992) J. Biol. Chem., 267, 22481–22485.

    PubMed  CAS  Google Scholar 

  27. Ostrander, D. B., Zhang, M., Mileykovskaya, E., Rho, M., and Dowhan, W. (2001) J. Biol. Chem., 276, 25262–25272.

    PubMed  CAS  Google Scholar 

  28. Zhang, M., Su, X., Mileykovskaya, E., Amoscato, A. A., and Dowhan, W. (2003) J. Biol. Chem., 278, 35204–35210.

    PubMed  CAS  Google Scholar 

  29. Krause, F., Reifschneider, N. H., Vocke, D., Seelert, H., Rexroth, S., and Dencher, N. A. (2004) J. Biol. Chem., 279, 48369–48375.

    PubMed  CAS  Google Scholar 

  30. Mileykovskaya, E., Zhang, M., and Dowhan, W. (2004) Biochim. Biophys. Acta (Abstr. Book of 13th Eur. Bioenergetics Conf., August 21–26, 2004, Pisa, Italy), 13, 260.

    Google Scholar 

  31. Fyfe, P. K., McAuley, K. E., Roszak, A. W., Isaacs, N. W., Cogdell, R. J., and Jones, M. R. (2001) Trends Biochem. Sci., 26, 106–112.

    PubMed  CAS  Google Scholar 

  32. Gilkerson, R. W., Selker, J. M., and Capaldi, R. A. (2003) FEBS Lett., 546, 355–358.

    PubMed  CAS  Google Scholar 

  33. Frey, T. G., Renken, C. W., and Perkins, G. A. (2002) Biochim. Biophys. Acta, 1555, 196–203.

    PubMed  CAS  Google Scholar 

  34. Renken, C., Siragusa, G., Perkins, G., Washington, L., Nulton, J., Salamon, P., and Frey, T. G. (2002) J. Struct. Biol., 138, 137–144.

    PubMed  CAS  Google Scholar 

  35. Bianchi, C., Genova, M. L., Parenti Castelli, G., and Lenaz, G. (2004) J. Biol. Chem., 279, 36562–36569.

    PubMed  CAS  Google Scholar 

  36. Bianchi, C., Fato, R., Genova, M. L., Parenti Castelli, G., and Lenaz, G. (2003) Biofactors, 18, 3–9.

    PubMed  CAS  Google Scholar 

  37. Petit, J. M., Huet, O., Gallet, P. F., Maftah, A., Ratinaud, M. H., and Julien, R. (1994) Eur. J. Biochem., 220, 871–879.

    PubMed  CAS  Google Scholar 

  38. Mileykovskaya, E., Dowhan, W., Birke, R. L., Zheng, D., Lutterodt, L., and Haines, T. H. (2001) FEBS Lett., 507, 187–190.

    PubMed  CAS  Google Scholar 

  39. Garcia Fernandez, M. I., Ceccarelli, D., and Muscatello, U. (2004) Analyt. Biochem., 328, 174–180.

    PubMed  CAS  Google Scholar 

  40. Piccotti, L., Mileykovskaya, E., Haines, T. H., and Dowhan, W. (2004) Biochim. Biophys. Acta (Abstr. Book of 13th Eur. Bioenergetics Conf., August 21–26, 2004, Pisa, Italy), 13, 261.

    Google Scholar 

  41. Deng, Y., Marko, M., Buttle, K. F., Leith, A., Mieczkowski, M., and Mannella, C. A. (1999) J. Struct. Biol., 127, 231–239.

    PubMed  CAS  Google Scholar 

  42. Deng, Y., Kohlwein, S. D., and Mannella, C. A. (2002) Protoplasma, 219, 160–167.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, University of Texas Houston, Medical School, TX, 77030, Houston s, USA

    E. Mileykovskaya, M. Zhang & W. Dowhan

Authors
  1. E. Mileykovskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. W. Dowhan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. Mileykovskaya.

Additional information

Translated from Biokhimiya, Vol. 70, No. 2, 2005, pp. 191–196.

Original Russian Text Copyright © 2005 by Mileykovskaya, Zhang, Dowhan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mileykovskaya, E., Zhang, M. & Dowhan, W. Cardiolipin in energy transducing membranes. Biochemistry (Moscow) 70, 154–158 (2005). https://doi.org/10.1007/s10541-005-0095-2

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10541-005-0095-2

Key words

Search

Navigation