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Efficacy of a Group Medication Adherence Intervention Among HIV Positive Women: The SMART/EST Women’s Project

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Abstract

This intervention sought to improve overall quality of life and health behavior in women living with human immunodeficiency virus (HIV). We contrasted the effect of a group cognitive behavioral stress management expressive supportive therapy (CBSM+) intervention plus a healthier lifestyles (HL) component with an individual educational/informational format plus HL on HIV-medication adherence. Women, n = 237, predominantly African-American and Latina, living with HIV were recruited from Miami, New York and New Jersey and randomized to group or individual conditions (ten weekly sessions) plus group or individual HL, i.e., four conditions. Women reported relatively high levels of adherence at baseline. Participants in any of the group conditions increased self-reported adherence and emotion-focused coping skills in comparison with individual participation. This study suggests that group interventions may be an important adjunct in increasing medication adherence for HIV positive women.

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References

  • Bangsberg, D. R., Hecht, F. M., Clague, H., Chalebois, E. D., Ciccarone, D., Chesney, M., et al. (2001). Provider assessment of adherence to HIV antiretroviral therapy. Journal of Acquired Immune Deficiency Syndrome, 26(Suppl. 5), 435–442.

    CAS  Google Scholar 

  • Baron, R. M., & Kenny D. A. (1986). The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173–1182.

    Article  PubMed  CAS  Google Scholar 

  • Barre-Sinoussi, F., Chermann, J. C., Rey, F., Nugeyre, M. T., Chamaret, S., & Gruest, J. (1983). Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS). Science, 220, 868–871.

    Article  PubMed  CAS  Google Scholar 

  • Boden, D., Hurley, A., Zhang, L., Cao, Y., Guo, Y., Jones, E., et al. (1999). HIV-1 drug resistance in newly infected individuals. Journal of the American Medical Association, 282, 1135–1141.

    Article  PubMed  CAS  Google Scholar 

  • Bogart, L. M., Gray-Bernhardt, M. L., Catz, S. L., Hartmann, B. R., & Otto-Salaj, L. L. (2002). Social and temporal comparisons made by individuals living with HIV disease: Relationships to adherence behavior. Journal of Applied Social Psychology, 32(Suppl. 8), 1551–1576.

    Article  Google Scholar 

  • Carpenter, C. C. J., Fischl, M. A., Hammer, S. M., Hirsch, M. S., Jacobsen, D. M., Katsenstein, D. A., et al. (2000). Antiretroviral therapy in adults updated recommendations of the international AIDS society—USA panel. Journal of the American Medical Association, 283, 381–390.

    Article  PubMed  CAS  Google Scholar 

  • Carver, C., Sheier, M., & Weintraub, J. D. (1989). Assessing coping strategies: A theoretically based approach. Journal of Personality and Social Psychology, 56, 267–283.

    Article  PubMed  CAS  Google Scholar 

  • Catz, S. L., Kelly, J. A., Bogart, L. M., Benotsch, E. G., & Mcauliffe, T. (2000). Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease. Health Psychology, 19(Suppl. 2), 124–133.

    Article  PubMed  CAS  Google Scholar 

  • Chesney, M., & Ickovics, J. (1997). For the recruitment, adherence and retention committee of the ACTG: Adherence to combination therapy in AIDS clinical trials. Presented at the annual meeting of the AIDS Clinical Trials Group, Washington.

  • Deeks, S., Beatty, G., Cohen, P. T., Grant, R., & Volberding, P. (1998). Viral load and CD+ T cell changes in patients failing potent protease inhibitor therapy [Abstract]. Fifth conference on Retroviruses and Opportunistic Infections, Chicago.

  • Gordillo, V., Del Amo, J., Soriano, V., & Gonzlez-Lahoz, J. (1999). Sociodemographic and psychological variables influencing adherence to antiretroviral therapy. AIDS, 13(Suppl. 13), 1763–1769.

    Article  PubMed  CAS  Google Scholar 

  • Goujard, C., Bernard, N., Sohier, N., Peyramond, D., Lancon, F., Chwalow, J., et al. (2003). Impact of a patient education program on adherence to HIV medication: A randomized clinical trial. Journal of Acquired Immune Deficiency Syndrome, 34(Suppl. 2), 191–194.

    Article  Google Scholar 

  • Hill, Z., Kendall, C., & Fernandez, M. (2003). Patterns of adherence to antiretrovirals: Why adherence has no simple measure. AIDS Patient Care STDs, 17(Suppl. 10), 519–525.

    Article  PubMed  Google Scholar 

  • Hogg, R. S., Chan, K. J., Wood, E., Craib, K. J., O'Shaughnessy, M. V., & Montaner, J. S. (2001). Rates of disease progression by baseline CD4 cell count and viral load after initiating triple-drug therapy. Journal of the American Medical Association, 286(20), 2597-2599.

    Google Scholar 

  • Horne R., Weinman J., & Hankins, M. (1991). The beliefs about medicines questionnaire: The development and evaluation of a new method for assessing the cognitive representation of medication. Psychology and Health, 12, 1–24.

    Google Scholar 

  • Ingledew, D. K., Hardy, L., Cooper, C. L., & Jemal, H. (1996). Health behaviours reported as coping strategies: A factor analytical study. British Journal of Health Psychology, 1, 263–281.

    Google Scholar 

  • Kalichman, S. C., Rompa, D., Difonzo, K., Simpson, D., Austin, J., Luke, W., et al. (2001). HIV treatment adherence in women living with HIV/AIDS: Research based on the information–motivation–behavioral skills model of health behavior. Journal of the Association of Nurses in AIDS Care, 12(Suppl. 4), 58–67.

    Article  PubMed  CAS  Google Scholar 

  • Kievits, T., van Gemen, B., van Strijp, D., Schukkink, R., Dircks, M., & Adriaanse, H. (1991). NASBA isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection. Journal of Virology Methods, 35(3), 273–286.

    Article  CAS  Google Scholar 

  • LaPerriere, A., Ironson, G., Antoni, M., Jones, D., Devieux, J., Ishii, M., et al. (2005). CBSM+ group intervention decreases depression in moderately depressed women with AIDS: The SMART/EST Women’s Project. Journal of Health Psychology, 10, 223–231.

    Article  PubMed  Google Scholar 

  • Malcolm, S. E., Ng, J. J., Rosen, R. K., & Stone, V. E. (2003). An examination of HIV/AIDS patients who have excellent adherence to HAART. AIDS Care, 15(Suppl. 2), 251–261.

    Article  PubMed  CAS  Google Scholar 

  • McPherson-Baker, S., Malow, R., Penedo, F., Jones, D., Schneiderman, N., & Klimas, N. (2000). Enhancing adherence to combination antiretroviral therapy in non-adherent HIV-positive men. AIDS Care, 12, 399–404.

    Article  PubMed  CAS  Google Scholar 

  • Pakenham, K. I. (1998). Specification of social support behaviours and network dimensions along the HIV continuum for gay men. Patient Education, 34(2), 147–157.

    Article  CAS  Google Scholar 

  • Paterson, D. L., Potoski, B., & Capitano, B. (2002). Measurement of adherence to antiretroviral medications. Journal of Acquired Immune Deficiency Syndrome, 31(Suppl. 3), S103–S106.

    Google Scholar 

  • Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., et al. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133(Suppl. 1), 21–30.

    PubMed  CAS  Google Scholar 

  • Reiter, G. S., Stewart, K. E., & Wojtusik, L. (2000). Elements of success in HIV clinical care: Multiple interventions that promote adherence. Topics in HIV Medicine, 8(Suppl. 5), 21–30.

    Google Scholar 

  • Remien, R. H., Hirky, A. E., Johnson, M. O., Weinhardt, L. S., Whittier, D., & Minh Le, G. (2003). Adherence to medication treatment: A qualitative study of facilitators and barriers among a diverse sample of HIV+ men and women in four U.S. cities. AIDS and Behavior, 7(Suppl. 1), 61–72.

    Article  Google Scholar 

  • Sankar, A., Luborsky, M., Schuman, P., & Roberts, G. (2002). Adherence discourse among African-American women taking HAART. AIDS Care, 14(Suppl. 2), 203–218.

    Article  PubMed  CAS  Google Scholar 

  • Segal-Isaacson, C. J., Tobin, J. N., Weiss, S. M., Brondolo, E., Vaughn, A., Wang, C., et al. (2006). Improving dietary habits in disadvantaged women with HIV/AIDS: The SMART/EST Women’s Project. AIDS and Behavior (in press).

  • Simoni, J. M., Frick, P. A., Lockhart, D., & Liebovitz, D. (2002). Mediators of social support and antiretroviral adherence among an indigent population in New York city. AIDS Patient Care and STDs, 16(Suppl. 9), 431–439.

    Article  PubMed  Google Scholar 

  • Spiegel, D., & Yalom, I. (1981). Group support for patients with metastatic breast cancer. Archives of General Psychiatry, 38, 527–533.

    PubMed  CAS  Google Scholar 

  • Stone, V. E., Hogan, J. W., Schuman, P., Rompalo, A. M., Howard, A. A., Korkontzelou, C., et al. (2001). Antiretroviral regimen complexity, self-reported adherence, and HIV patient’s understanding of their regimens: Survey of women in the HER study. Journal of Acquired Immune Deficiency Syndrome, 28(Suppl. 2), 124–131.

    CAS  Google Scholar 

  • Wagner, G. J., Remien, R. H., Carballo-Dieguez, A., & Dolezal, C. (2002). Correlates of adherence to combination antiretroviral therapy among members of HIV-positive mixed status couples. AIDS Care, 14(Suppl. 1), 105–109.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

Funded by NIMH Grant Nos. 1R01-MH 55463 and 1R01-MH61208. We would like to acknowledge all those in our research teams at the University of Miami School of Medicine, the Clinical Directors Network and St John’s University, as well as community sites providing referrals, and most importantly, the women participating in this research.

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Correspondence to Deborah L. Jones.

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Jones, D.L., McPherson-Baker, S., Lydston, D. et al. Efficacy of a Group Medication Adherence Intervention Among HIV Positive Women: The SMART/EST Women’s Project. AIDS Behav 11, 79–86 (2007). https://doi.org/10.1007/s10461-006-9165-8

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