Abstract
Skeletal muscle metastasis from esophageal squamous cell carcinoma is an unusual entity. A 72-year-old man underwent a subtotal esophagectomy for advanced esophageal squamous cell carcinoma. Mediastinal lymph node metastases developed 36 months after operation, and the patient received chemoradiotherapy. He complained about two painful, subcutaneous masses in the upper part of the left arm at 3 months after the end of chemoradiotherapy. Histopathological examination of tissue specimens obtained by explorative surgery showed skeletal muscle metastases from poorly differentiated squamous cell carcinoma. The patient died of multiple metastases 7 months after chemoradiotherapy. This is considered a very rare case of metastasis from squamous cell carcinoma of the esophagus to the triceps muscle of the left arm.
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Hayata K, Iwahashi M, Nakamori M, Nakamura M, Naka T, Ojima T, et al. Skeletal muscle metastasis from esophageal cancer: a report of two cases and a review of the literature. Esophagus. 2009;6:117–21.
Heffernan E, Fennelly D, Collins CD. Multiple metastases to skeletal muscle from carcinoma of the esophagus detected by FDG PET–CT imaging. Clin Nucl Med. 2006;31:810–1.
Heyer CM, Rduch GJ, Zgoura P, Stachetzki U, Voigt E, Nicolas V. Metastasis to skeletal muscle from esophageal adenocarcinoma. Scand J Gastroenterol. 2005;40:1000–4.
Pretorius ES, Fishman EK. Helical CT of skeletal muscle metastases from primary carcinomas. AJR Am J Roentgenol. 2000;174:401–4.
Rehman SU, Cope DW, Basile JN. Metastatic gastroesophageal adenocarcinoma to skeletal muscle: a unique event. South Med J. 2002;95:1076–8.
Wu G, Bybel B, Brunken R, Lin H, Neumann D. PET detection of solitary distant skeletal muscle metastasis of esophageal adenocarcinoma. Clin Nucl Med. 2005;30:335–7.
Hsieh TC, Sun SS, Wu YC, Yen KY, Kao CH. Mimicry of physiological urinary FDG excretion: squamous cell carcinoma of esophagus metastasizing to psoas muscle. Clin Nucl Med. 2011;36:36–7.
Uygur S, Aral M, Kaya B, Ozmen S, Ozgun G, Latifoglu O. Giant temporalis muscle metastasis of esophageal carcinoma. J Craniofac Surg. 2011;22:736–7.
Norris WE, Perry JL, Moawad FJ, Horwhat JD. An unusual presentation of metastatic esophageal adenocarcinoma presenting as thigh pain. J Gastrointest Liver Dis. 2009;18:371–4.
Fukunaga T, Okazumi S, Koide Y, Isono K, Imazeki K. Evaluation of esophageal cancers using fluorine-18-fluorodeoxyglucose PET. J Nucl Med. 1998;39:1002–7.
Herring CL, Jr., Harrelson JM, Scully SP. Metastatic carcinoma to skeletal muscle. A report of 15 patients. Clin Orthop Relat Res. 1998;355:272–81.
Tuoheti Y, Okada K, Osanai T, Nishida J, Ehara S, Hashimoto M, et al. Skeletal muscle metastases of carcinoma: a clinicopathological study of 12 cases. Jpn J Clin Oncol. 2004;34:210–4.
Damron TA, Heiner J. Distant soft tissue metastases: a series of 30 new patients and 91 cases from the literature. Ann Surg Oncol. 2000;7:526–34.
Plaza JA, Perez-Montiel D, Mayerson J, Morrison C, Suster S. Metastases to soft tissue: a review of 118 cases over a 30-year period. Cancer. 2008;112:193–203.
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Matsutani, T., Matsuda, A., Yoshida, H. et al. Resection of skeletal muscle metastases from squamous cell carcinoma of the esophagus: case report and literature review. Esophagus 10, 42–45 (2013). https://doi.org/10.1007/s10388-012-0344-6
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DOI: https://doi.org/10.1007/s10388-012-0344-6