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Diffusion tensor imaging and fiber tractography in brain malformations

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Abstract

Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and quantitative information about the micro-architecture of white matter. DTI and its post-processing tool fiber tractography (FT) have been increasingly used in the last decade to investigate the microstructural neuroarchitecture of brain malformations. This article aims to review the use of DTI and FT in the evaluation of a variety of common, well-described brain malformations, in particular by pointing out the additional information that DTI and FT renders compared with conventional MR sequences. In addition, the relevant existing literature is summarized.

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Acknowledgments

Dr. Poretti was supported financially by the Anna Mueller Grocholswi-Foundation, Zurich, Switzerland.

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Authors and Affiliations

  1. Division of Pediatric Radiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 600 N. Wolfe St., Nelson Basement, B-173, Baltimore, MD, 21287-0842, USA

    Andrea Poretti, Avner Meoded & Thierry A. G. M. Huisman

  2. Pediatric Neuroradiology, G. Gaslini Institue, Genova, Italy

    Andrea Rossi

  3. Department of Neuroradiology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Charles Raybaud

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  1. Andrea Poretti
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  2. Avner Meoded
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  3. Andrea Rossi
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  5. Thierry A. G. M. Huisman
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Correspondence to Thierry A. G. M. Huisman.

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Poretti, A., Meoded, A., Rossi, A. et al. Diffusion tensor imaging and fiber tractography in brain malformations. Pediatr Radiol 43, 28–54 (2013). https://doi.org/10.1007/s00247-012-2428-9

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