Zusammenfassung
Sertoli-Zell-Tumoren stellen mit einem Anteil von 1,5 % aller Hodentumoren eine sehr seltene Subklassifikation dar. Im seltenen Fall der Metastasierung besteht für die Patienten eine infauste Prognose. Bisher sind weltweit 36 maligne Krankheitsverläufe dokumentiert. Wir berichten über einen Patienten mit Nachweis eines lymphogen metastasierten Sertoli-Zell-Tumors, der nun bereits 24 Monate nach erfolgter Orchiektomie und ausgedehnter retroperitonealer Lymphadenektomie rezidivfrei ist.
Abstract
Sertoli cell tumors are a rare malignancy which account for approximately 1.5 % of all testicular tumors. Although malignant Sertoli cell tumors are uncommon, they are associated with a poor prognosis. So far 36 cases of malignant courses of disease have been described. We present a patient with a lymphogenic metastasized Sertoli cell tumor, who 24 months after orchiectomy and extended retroperitoneal lymphadenectomy is relapse-free.
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Literatur
Adayener C et al (2008) Sertoli cell tumor of the testis: a case with late metastasis. Int Urol Nephrol 40:1005–1008
Blick C, Abdelhadi S, Bailey D et al (2008) A unique case of a malignant Sertoli cell tumour with cutaneous metastasis. ScientificWorldJournal 8:95–97
Cano-Valdez AM, Chanona-Vilchis J, Dominguez-Malagon H (1999) Large cell calcifying Sertoli cell tumor of the testis: a clinicopathological, immunohistochemical, and ultrastructural study of two cases. Ultrastruct Pathol 23:259–265
Demir A, Onol FF, Turkeri L (2003) Case report: malignant Sertoli cell tumor of the testis in an adult. Int Urol Nephrol 35:515–516
Henley JD, Young RH, Ulbright TM (2002) Malignant Sertoli cell tumors of the testis: a study of 13 examples of a neoplasm frequently misinterpreted as seminoma. Am J Surg Pathol 26(5):541–550
Kratzer SS et al (1997) Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature. Am J Surg Pathol 21:1271–1280
Lindegaard Madsen E, Morck Hultberg B (1990) Metastasizing Sertoli cell tumours of the human testis – a report of two cases and a review of the literature. Acta Oncol 29:946–949
Mosharafa AA et al (2003) Does retroperitoneal lymph node dissection have a curative role for patients with sex cord-stromal testicular tumors? Cancer 98:753–757
Nogales FF, Andujar M, Zuluaga A, Garcia-Puche JL (1995) Malignant large cell calcifying Sertoli cell tumor of the testis. J Urol 153:1935–1937
Petersson F et al (2010) Large cell calcifying Sertoli cell tumor: a clinicopathologic study of 1 malignant and 3 benign tumors using histomorphology, immunohistochemistry, ultrastructure, comparative genomic hybridization, and polymerase chain reaction analysis of the PRKAR1A gene. Hum Pathol 41:552–559
Sassa N et al (2008) Case report of malignant sertoli cell tumor. Nihon Hinyōkika Gakkai 99:656–659
Interessenkonflikt
K. Günzel, H. Wegner, H. Cash, P. Lohneis, C. Kempkensteffen, K. Miller und S. Hinz geben an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.
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Günzel, K., Wegner, H., Cash, H. et al. Maligner Sertoli-Zell-Tumor des Hodens. Urologe 54, 1115–1117 (2015). https://doi.org/10.1007/s00120-015-3814-3
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DOI: https://doi.org/10.1007/s00120-015-3814-3