Abstract
Senior patients are at hight risk of polymorbidity which may correspond with hight risk of polypharmacy. Benefit of pharmacotherapy on one hand and risk of pharmacotherapy on the other hand are two different scales of one balance we have to measure on.
The paper shows basic principles of safe and efficient pharmacotherapy in the elderly – including inappropriate psychotropic drugs and drug-drug interactions which should be avoided.
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Abbreviations
- BZD:
-
benzodiazepines
- CYP:
-
cytochrome P450 superfamily
- ECG:
-
electrocardiography
- MAO inhibitors:
-
monoamine oxidase inhibitors
- MASSA:
-
melatonin agonist and selective serotonin antagonist
- NASSA:
-
noradrenergic and specific serotonergic antidepressant
- NDRI:
-
noradrenergic and dopaminergic reuptake inhibitor
- NSAID’s:
-
nonsteroid anti-inflammatory drugs
- QT:
-
QT interval in electrocardiogram
- SARI:
-
serotonin antagonist reuptake inhibitor
- SIADH:
-
syndrome of inappropriate antidiuretic hormone secretion
- SNRI:
-
serotonin noradrenaline reuptake inhibitors
- SSRI:
-
selective serotonin reuptake inhibitors
- TCA’s:
-
tricyclic antidepressants
- “Z”-agents:
-
zolpidem zopiclone, zaleplone
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Luzny, J. (2013). Polypharmacy and Potentially Inappropriate Medication Use Among Elders with Dementia. In: Ritsner, M. (eds) Polypharmacy in Psychiatry Practice, Volume II. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5799-8_13
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DOI: https://doi.org/10.1007/978-94-007-5799-8_13
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