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Generation of Synthetic 4D Cardiac CT Images for Guidance of Minimally Invasive Beating Heart Interventions

  • Conference paper
Information Processing in Computer-Assisted Interventions (IPCAI 2013)

Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 7915))

Abstract

Off-pump beating heart surgery requires a guidance system that would show both pertinent cardiac anatomy and dynamic motion both peri- and intra-operatively. Optimally, the guidance system should show high quality images and models in a cost-effective way and can be easily integrated into standard clinical workflow. However, such a goal is difficult to accomplish by a single image modality. In this paper we introduce a method of generating a synthetic 4D cardiac CT dataset using a single (static) CT, along with 4D ultrasound images. These synthetic images can be combined with intra-operative ultrasound during the surgery to provide an intuitive and effective augmented virtuality guidance system. The generation method obtains patient specific cardiac motion information by performing non-rigid registrations between pre-operative 4D ultrasound images and applies the deformation to a static CT image to deform it into a series of dynamic CT images. Validations was performed by comparing the synthetic CT images to real dynamic CT images.

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References

  1. Dotty, D.B., Flores, J.H., Doty, J.R.: Cardiac valve operations using a partial sternotomy technique. J. Card. Surg. 15, 35–42 (2000)

    Article  Google Scholar 

  2. Vassiliades, T.A., Block, P.C., Cohn, L.H.: The clinical development of percutaneous heart valve technology. J. Thorac. Cardiovasc. Surg. 129, 970–976 (2005)

    Article  Google Scholar 

  3. McVeigh, E.R., Guttman, M.A., Kellman, P., Raval, A.A., Lederman, R.J.: Real-time interactive MRI for cardiovascular interventions. Acad. Radiol. 12, 1221–1227 (2005)

    Article  Google Scholar 

  4. Linte, C.A., Moore, J., Wedlake, C., Bainbridge, D., Guiraudon, G.M., Jones, D.L., Peters, T.M.: Inside the beating heart: An in vivo feasibility study on fusing pre- and intra-operative imaging for minimally invasive therapy. Journal of Computer Assisted Radiology and Surgery 4(2), 113–123 (2009)

    Article  Google Scholar 

  5. Linte, C.A., Moore, J., Wiles, A.D., Wedlake, C., Peters, T.M.: Virtual reality-enhanced ultrasound guidance: A novel technique for intracardiac interventions. Comput Aided Surg. 13(2), 82–94 (2008)

    Google Scholar 

  6. Huang, X., Hill, N.A., Ren, J., Guiraudon, G.M., Boughner, D.R., Peters, T.M.: Dynamic 3D ultrasound and MR image registration of the beating heart. In: Duncan, J.S., Gerig, G. (eds.) MICCAI 2005. LNCS, vol. 3750, pp. 171–178. Springer, Heidelberg (2005)

    Google Scholar 

  7. Shuman, W.P., Branch, K.R., May, J.M., Mitsumori, L.M., Lockhart, D.W., Dubinsky, T.J., Warren, B.H., Caldwell, J.H.: Prospective versus retrospective ECG gating for 64-detector CT of the coronary arteries: comparison of image quality and patient radiation dose. Radiology 248(2), 431–437 (2008)

    Article  Google Scholar 

  8. Li, F., Lang, P., Rajchl, M., Chen, E.C.S., Guiraudon, G., Peters, T.M.: Towards real-time 3D US-CT registration on the beating heart for guidance of minimally invasive cardiac interventions. In: Proc. SPIE, vol. 8316, p. 831615 (2012)

    Google Scholar 

  9. Ledesma-Carbayo, M.J., Kybic, J., Desco, M., Santos, A., Suhling, M., Hunziker, P., Unser, M.: Spatio-temporal nonrigid registration for ultrasound cardiac motion estimation. IEEE Trans. Med. Imaging 24(9), 1113–1126 (2005)

    Article  Google Scholar 

  10. Shi, W., Zhuang, X., Wang, H., Duckett, S., Luong, D.V., Tobon-Gomez, C., Tung, K., Edwards, P.J., Rhode, K.S., Razavi, R.S., Ourselin, S., Rueckert, D.: A Comprehensive Cardiac Motion Estimation Framework Using Both Untagged and 3-D Tagged MR Images Based on Nonrigid Registration. IEEE Trans. Med. Imaging 31(6), 1263–1275 (2012)

    Article  Google Scholar 

  11. Wierzbicki, M., Drangova, M., Guiraudon, G.M., Peters, T.M.: Validation of dynamic heart models obtained using non-linear registration for virtual reality training, planning, and guidance of minimally invasive cardiac surgeries. Medical Image Analysis 8(3), 387–401 (2004)

    Article  Google Scholar 

  12. Sundara, H., Littb, H., Shen, D.: Estimating myocardial motion by 4D image warping. Journal Pattern Recognition 42(11), 2514–2526 (2009)

    Article  Google Scholar 

  13. Modat, M., Taylor, Z.A., Barnes, J., Hawkes, D.J., Fox, N.C., Ourselin, S.: Fast free-form deformation using graphics processing units. Comput. Meth. Prog. Bio. 98(3), 278–284 (2010)

    Article  Google Scholar 

  14. Peyrat, J.M., Delingette, H., Sermesant, M., Pennec, X., Xu, C., Ayache, N.: Registration of 4D time-series of cardiac images with multichannel Diffeomorphic Demons. Med. Image. Comput. Comput. Assist. Interv. 11(Pt. 2), 972–979 (2008)

    Google Scholar 

  15. Vemuri, B.C., Ye, J., Chen, Y., Leonard, C.M.: Image registration via level-set motion: applications to atlas-based segmentation. Medical Image Analysis 7, 1–20 (2003)

    Article  Google Scholar 

  16. Pluim, J.P.W., Antoine Maintz, J.B., Viergever, M.A.: Mutual information based registration of medical images: a survey. IEEE Trans. Med. Imaging 22(8), 986–1004 (2003)

    Article  Google Scholar 

  17. Rogalla, P., Kloeters, C., Hein, P.A.: CT technology overview: 64-slice and beyond. Radiol. Clin. North Am. 47(1), 1–11 (2009)

    Article  Google Scholar 

  18. Coupé, P., Hellier, P., Kervrann, C., Barillot, C.: NonLocal Means-based Speckle Filtering for Ultrasound Images. IEEE Transactions on Image Processing 18(10), 2221–2229 (2009)

    Article  MathSciNet  Google Scholar 

  19. Buades, A., Coll, B., Morel, J.M.: A review of image denoising algorithms, with a new one. Multiscale Modeling & Simulation 4(2), 490–530 (2005)

    Article  MathSciNet  MATH  Google Scholar 

  20. Rajchl, M., Yuan, J., Ukwatta, E., Peters, T.M.: Fast interactive multi-region cardiac segmentation with linearly ordered labels. In: 9th IEEE International Symposium on Biomedical Imaging (ISBI), pp. 1409–1412 (2012)

    Google Scholar 

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Li, F.P., Rajchl, M., White, J.A., Goela, A., Peters, T.M. (2013). Generation of Synthetic 4D Cardiac CT Images for Guidance of Minimally Invasive Beating Heart Interventions. In: Barratt, D., Cotin, S., Fichtinger, G., Jannin, P., Navab, N. (eds) Information Processing in Computer-Assisted Interventions. IPCAI 2013. Lecture Notes in Computer Science, vol 7915. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38568-1_2

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  • DOI: https://doi.org/10.1007/978-3-642-38568-1_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-38567-4

  • Online ISBN: 978-3-642-38568-1

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