Abstract
Many clinical situations require a precise assessment of corneal structures. However, the resolution of ophthalmic instruments such as the slit-lamp is limited and, for ophthalmologists, it has always been a challenge to evaluate qualitatively and quantitatively the microscopic structures of the cornea. Recently, new imaging techniques have thus been developed to overcome these limitations of light biomicroscopy.
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Zhivov A, Stachs O, Kraak R et al (2006) In vivo confocal microscopy of the ocular surface. Ocul Surf 4(2):81–93
Labbe A, Khammari C, Dupas B et al (2009) Contribution of in vivo confocal microscopy to the diagnosis and management of infectious keratitis. Ocul Surf 7(1):41–52
Brasnu E, Bourcier T, Dupas B et al (2007) In vivo confocal microscopy in fungal keratitis. Br J Ophthalmol 91(5):588–591
Kaufman SC, Musch DC, Belin MW et al (2004) Confocal microscopy: a report by the American Academy of Ophthalmology. Ophthalmology 111(2):396–406
Niederer RL, McGhee CN (2010) Clinical in vivo confocal microscopy of the human cornea in health and disease. Prog Retin Eye Res 29(1):30–58
Patel DV, Grupcheva CN, McGhee CN (2005) Imaging the microstructural abnormalities of meesmann corneal dystrophy by in vivo confocal microscopy. Cornea 24(6):669–673
Labbe A, Nicola RD, Dupas B et al (2006) Epithelial basement membrane dystrophy: evaluation with the HRT II Rostock Cornea Module. Ophthalmology 113(8):1301–1308
Kobayashi A, Sugiyama K (2007) In vivo laser confocal microscopy findings for Bowman’s layer dystrophies (Thiel-Behnke and Reis-Bucklers corneal dystrophies). Ophthalmology 114(1):69–75
Kaufman SC, Kaufman HE (2006) How has confocal microscopy helped us in refractive surgery? Curr Opin Ophthalmol 17(4):380–388
Jalbert I, Stapleton F, Papas E et al (2003) In vivo confocal microscopy of the human cornea. Br J Ophthalmol 87(2):225–236
Sonigo B, Iordanidou V, Chong-Sit D et al (2006) In vivo corneal confocal microscopy comparison of intralase femtosecond laser and mechanical microkeratome for laser in situ keratomileusis. Invest Ophthalmol Vis Sci 47(7):2803–2811
Erie JC, Nau CB, McLaren JW et al (2004) Long-term keratocyte deficits in the corneal stroma after LASIK. Ophthalmology 111(7):1356–1361
Calvillo MP, McLaren JW, Hodge DO, Bourne WM (2004) Corneal reinnervation after LASIK: prospective 3-year longitudinal study. Invest Ophthalmol Vis Sci 45(11):3991–3996
Niederer RL, Perumal D, Sherwin T, McGhee CN (2007) Corneal innervation and cellular changes after corneal transplantation: an in vivo confocal microscopy study. Invest Ophthalmol Vis Sci 48(2):621–626
Niederer RL, Sherwin T, McGhee CN (2007) In vivo confocal microscopy of subepithelial infiltrates in human corneal transplant rejection. Cornea 26(4):501–504
Mazzotta C, Balestrazzi A, Traversi C et al (2007) Treatment of progressive keratoconus by riboflavin-UVA-induced cross-linking of corneal collagen: ultrastructural analysis by Heidelberg Retinal Tomograph II in vivo confocal microscopy in humans. Cornea 26(4):390–397
Labbe A, Dupas B, Hamard P, Baudouin C (2005) In vivo confocal microscopy study of blebs after filtering surgery. Ophthalmology 112(11):1979
Prakash G, Agarwal A, Jacob S (2009) Comparison of Fourier-domain and time-domain optical coherence tomography for assessment of corneal thickness and intersession repeatability. Am J Ophthalmol 148(2):282–90.e2
Simpson T, Fonn D (2008) Optical coherence tomography of the anterior segment. Ocul Surf 6(3):117–127
Knuttel A, Bonev S, Knaak W (2004) New method for evaluation of in vivo scattering and refractive index properties obtained with optical coherence tomography. J Biomed Opt 9(2):265–273
Li Y, Netto MV, Shekhar R et al (2007) A longitudinal study of LASIK flap and stromal thickness with high-speed optical coherence tomography. Ophthalmology 114(6):1124–1132
Stahl JE, Durrie DS, Schwendeman FJ, Boghossian AJ (2007) Anterior segment OCT analysis of thin IntraLase femtosecond flaps. J Refract Surg 23(6):555–558
Ustundag C, Bahcecioglu H, Ozdamar A et al (2000) Optical coherence tomography for evaluation of anatomical changes in the cornea after laser in situ keratomileusis. J Cataract Refract Surg 26(10):1458–1462
Baikoff G (2006) Anterior segment OCT and phakic intraocular lenses: a perspective. J Cataract Refract Surg 32(11):1827–1835
Shih CY, Ritterband DC, Palmiero PM (2009) The use of postoperative slit-lamp optical coherence tomography to predict primary failure in descemet stripping automated endothelial keratoplasty. Am J Ophthalmol 147(5):796–800, e1
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© 2013 Springer-Verlag Berlin Heidelberg
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Labbé, A., Denoyer, A., Baudouin, C. (2013). Advance in Corneal Imaging. In: Reinhard, T., Larkin, F. (eds) Corneal Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28747-3_4
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DOI: https://doi.org/10.1007/978-3-642-28747-3_4
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