Abstract
Today, a variety of different nanoparticles are used in various applications. In particular, super-paramagnetic iron oxide nanoparticles (or SPIONs) are used in vitro for cell separation and in vivo for hyperthermia or as contrast agent for magnetic resonance imaging (MRI). However, in Magnetic Particle Imaging (MPI), SPIONs play a fundamental role as tracer material. In addition to the overall size of the particles and the particle coating, which are important for medical applications, it is the magnetic core diameter that is relevant for the performance in MPI applications. In general, for in vivo applications, the stability of the particles is of key importance. Therefore, in this paper, the stability of the SPIONs have been analyzed in different particle suspension media.
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Paschen, H., Coenen, C., Fleischer, T., Grünwald, R., Oertel, D., Revermann, C.: Nanotechnologie – Forschung, Entwicklung, Anwendung. Springer, Heidelberg (2004)
Leyendecker, S.: Nanomaterialien in Architektur. In: Innenarchitektur und Design, Birkhäuser, Basel (2008)
Bönnemann, H., Brijour, W., Brinkmann, R.: Angew. Chemie 103(10), 1344–1346 (1991)
Gupta, A.K., Gupta, M.: Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 26(18), 3995–4021 (2005)
Mornet, S., Vasseur, S., Grasset, F., Verveka, P., Goglio, G., Demourgues, A., Portier, J., Pollert, E., Duguet, E.: Prog. Solid State Chem. 34, 237 (2006)
Elliott, D.W., Zhang, W.X.: Environ. Sci. Technol. 35, 4922 (2001)
Gulyaev, A.E., et al.: Significant transport of doxorubicin into brain with polysorbate 80-coated nanoparticles. Pharm. Res. 16(10), 1564–1569 (1999)
Lanza, G.M., Lamerichs, R., Caruthers, S., Wickline, A.S.: Molekulare Bildgebung in der MRT mit paramagnetischen Nanopartikeln. Medicamundi 6, 11–17 (2004)
Groman, E.V., Josephson, L.: US Patent 4.770.183 (1983)
Gleich, B., Weizenecker, J.: Tomographic imaging using the nonlinear response of magnetic particles. Nature 435, 1214–1217 (2005)
Lüdtke-Buzug, K., Biederer, S., Sattel, T., Knopp, T., Buzug, T.M.: Preparation and Characterization of Dextran-Covered Fe3O4 Nanoparticles for Magnetic Particle Imaging. In: Vander Sloten, J., Verdonck, P., Nyssen, M., Haueisen, J. (eds.) IFMBE Proceedings. ECIFMBE 2008, vol. 22, pp. 2343–2346. Springer, Heidelberg (2008)
Lüdtke-Buzug, K., Biederer, S., Sattel, T.F., Knopp, T., Buzug, T.M.: Particle-Size Distribution of Dextran- and Carboxydextran-Coated Superparamagnetic Nanoparticles for Magnetic Particle Imaging. In: World Congress on Medical Physics and Biomedical Engineering. IFMBE, vol. 25/VIII, pp. 226–229. Springer, Heidelberg (2009)
Lüdtke-Buzug, K., Rapoport, D., Schneider, D.: Characterization of Iron-Oxide Loaded Adult Stem Cells for Magnetic Particle Imaging in Targeted Cancer Therapy. In: Proc. of AIP Conf., vol. 1311, pp. 244–248 (2010)
Biederer, S., Knopp, T., Sattel, T.F., Lüdtke-Buzug, K., Gleich, B., Weizenecker, J., Borgert, J., Buzug, T.M.: Magnetization Response Spectroscopy of Superparamagnetic Nanoparticles for Magnetic Particle Imaging. Journal of Physics D: Applied Physics 42(20), 7 (2009)
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Lüdtke-Buzug, K., Borchers, C. (2012). Superparamagnetic Iron Oxide Nanoparticles: Evaluation of Stability of SPIONs in Different Milieu for Magnetic Particle Imaging. In: Buzug, T., Borgert, J. (eds) Magnetic Particle Imaging. Springer Proceedings in Physics, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-24133-8_17
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DOI: https://doi.org/10.1007/978-3-642-24133-8_17
Publisher Name: Springer, Berlin, Heidelberg
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